ENSG00000155363

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000357443 ENSG00000155363 HEK293_OSMI2_2hA HEK293_TMG_2hB MOV10 protein_coding protein_coding 31.41085 52.26042 24.25216 2.7191 0.7413552 -1.107286 7.470263 15.7214905 5.239338 0.4940577 0.8923480 -1.5834481 0.22057083 0.30330000 0.21523333 -0.08806667 0.308158243 0.001054963 FALSE  
ENST00000369645 ENSG00000155363 HEK293_OSMI2_2hA HEK293_TMG_2hB MOV10 protein_coding protein_coding 31.41085 52.26042 24.25216 2.7191 0.7413552 -1.107286 10.052210 15.5746747 8.443989 1.3688000 0.8301616 -0.8824238 0.32075000 0.29976667 0.35073333 0.05096667 0.725024811 0.001054963 FALSE  
ENST00000471160 ENSG00000155363 HEK293_OSMI2_2hA HEK293_TMG_2hB MOV10 protein_coding processed_transcript 31.41085 52.26042 24.25216 2.7191 0.7413552 -1.107286 4.422462 9.6248791 2.568325 2.3259550 1.4216448 -1.9018327 0.12902500 0.18046667 0.10293333 -0.07753333 0.722648422 0.001054963 FALSE  
ENST00000685268 ENSG00000155363 HEK293_OSMI2_2hA HEK293_TMG_2hB MOV10 protein_coding retained_intron 31.41085 52.26042 24.25216 2.7191 0.7413552 -1.107286 1.342470 0.9296704 1.791881 0.2804277 0.2048834 0.9392773 0.05049167 0.01803333 0.07386667 0.05583333 0.004355779 0.001054963 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000155363 E001 0.1515154 0.0425770150 2.191403e-01   1 112673141 112673451 311 + 0.171 0.000 -9.269
ENSG00000155363 E002 3.1603660 0.0049029256 4.111439e-01 5.547284e-01 1 112674421 112674658 238 + 0.466 0.611 0.679
ENSG00000155363 E003 2.8199748 0.2317517398 8.206419e-01 8.868944e-01 1 112674659 112674683 25 + 0.588 0.517 -0.331
ENSG00000155363 E004 3.9573052 0.1199081342 6.459229e-01 7.579745e-01 1 112674684 112674694 11 + 0.726 0.617 -0.458
ENSG00000155363 E005 4.8773550 0.1028883423 8.946291e-01 9.366806e-01 1 112674695 112674697 3 + 0.763 0.715 -0.195
ENSG00000155363 E006 8.4011958 0.0372944993 1.454138e-01 2.554142e-01 1 112674698 112674705 8 + 1.063 0.858 -0.765
ENSG00000155363 E007 13.5767254 0.0018219873 6.872129e-03 2.089264e-02 1 112674706 112674708 3 + 1.274 1.029 -0.878
ENSG00000155363 E008 34.6822434 0.0008925954 1.689910e-01 2.868765e-01 1 112674709 112674719 11 + 1.558 1.478 -0.274
ENSG00000155363 E009 47.6703726 0.0167689326 2.871485e-01 4.276241e-01 1 112674720 112674729 10 + 1.695 1.611 -0.285
ENSG00000155363 E010 2.1454975 0.0069986706 2.557056e-02 6.306042e-02 1 112674737 112674744 8 + 0.686 0.322 -1.806
ENSG00000155363 E011 29.5812754 0.0007458076 4.240090e-01 5.670104e-01 1 112674745 112674831 87 + 1.391 1.455 0.222
ENSG00000155363 E012 47.4480007 0.0019979592 6.320998e-01 7.470098e-01 1 112674832 112674847 16 + 1.607 1.643 0.123
ENSG00000155363 E013 108.5116332 0.0075050376 3.426433e-01 4.866497e-01 1 112674848 112674911 64 + 2.021 1.975 -0.153
ENSG00000155363 E014 128.9872043 0.0081961301 1.882870e-01 3.115810e-01 1 112674912 112674989 78 + 2.107 2.044 -0.211
ENSG00000155363 E015 129.2578811 0.0029429246 4.371170e-02 9.785699e-02 1 112674990 112675049 60 + 2.115 2.040 -0.253
ENSG00000155363 E016 1.2554357 0.2762925389 6.174296e-02 1.295595e-01 1 112675486 112676679 1194 + 0.590 0.159 -2.708
ENSG00000155363 E017 0.5138669 0.0201846416 2.099320e-01 3.384564e-01 1 112676680 112676750 71 + 0.293 0.086 -2.127
ENSG00000155363 E018 0.0000000       1 112685035 112685162 128 +      
ENSG00000155363 E019 13.4033631 0.0016401171 4.797701e-02 1.055963e-01 1 112686966 112687106 141 + 1.227 1.047 -0.648
ENSG00000155363 E020 37.3058918 0.0036779276 1.098556e-07 1.107718e-06 1 112688328 112688934 607 + 1.743 1.414 -1.126
ENSG00000155363 E021 248.0839393 0.0030093715 2.242122e-05 1.374238e-04 1 112688935 112689138 204 + 2.440 2.302 -0.461
ENSG00000155363 E022 289.3536796 0.0019142713 9.515352e-08 9.699515e-07 1 112689415 112689650 236 + 2.513 2.364 -0.496
ENSG00000155363 E023 125.0739931 0.0002342514 7.146142e-06 4.909931e-05 1 112689840 112689866 27 + 2.148 2.006 -0.476
ENSG00000155363 E024 217.1043879 0.0002129369 2.338784e-07 2.213165e-06 1 112689867 112689993 127 + 2.374 2.248 -0.418
ENSG00000155363 E025 207.2236972 0.0002461069 1.275599e-04 6.480688e-04 1 112689994 112690098 105 + 2.333 2.239 -0.315
ENSG00000155363 E026 207.6081147 0.0001764790 2.859634e-06 2.149968e-05 1 112691665 112691799 135 + 2.347 2.232 -0.383
ENSG00000155363 E027 240.3090843 0.0001858340 2.601592e-05 1.571081e-04 1 112692761 112692929 169 + 2.397 2.301 -0.319
ENSG00000155363 E028 3.2211997 0.0365472415 9.400329e-01 9.663379e-01 1 112693716 112693728 13 + 0.590 0.586 -0.016
ENSG00000155363 E029 13.8306853 0.0104832907 1.506663e-01 2.625756e-01 1 112693729 112694017 289 + 1.215 1.073 -0.507
ENSG00000155363 E030 210.3344820 0.0014536640 2.922754e-02 7.044617e-02 1 112694018 112694172 155 + 2.315 2.255 -0.199
ENSG00000155363 E031 246.5435356 0.0002251147 1.505201e-01 2.623860e-01 1 112694453 112694629 177 + 2.361 2.333 -0.093
ENSG00000155363 E032 265.4264560 0.0001607691 9.602397e-02 1.844021e-01 1 112694749 112694896 148 + 2.395 2.363 -0.106
ENSG00000155363 E033 2.5894492 0.0168089485 2.166999e-04 1.035519e-03 1 112694897 112695415 519 + 0.861 0.274 -2.832
ENSG00000155363 E034 289.2569915 0.0001678905 1.315874e-01 2.363460e-01 1 112695416 112695574 159 + 2.429 2.403 -0.088
ENSG00000155363 E035 267.1866630 0.0001939998 7.405758e-01 8.299606e-01 1 112696148 112696251 104 + 2.364 2.380 0.054
ENSG00000155363 E036 3.5439001 0.0095397598 4.936405e-02 1.080279e-01 1 112696252 112696283 32 + 0.799 0.506 -1.264
ENSG00000155363 E037 1.9833729 0.0071447531 5.442848e-02 1.170052e-01 1 112696284 112696436 153 + 0.640 0.322 -1.613
ENSG00000155363 E038 244.1769283 0.0002268192 8.565493e-01 9.112850e-01 1 112696437 112696534 98 + 2.334 2.337 0.011
ENSG00000155363 E039 236.0458604 0.0001944347 4.580888e-02 1.016808e-01 1 112696630 112696738 109 + 2.277 2.337 0.201
ENSG00000155363 E040 184.1709678 0.0002210012 2.975654e-04 1.369770e-03 1 112696739 112696818 80 + 2.127 2.244 0.391
ENSG00000155363 E041 140.2622661 0.0002622530 2.123728e-01 3.413283e-01 1 112696819 112696846 28 + 2.059 2.109 0.167
ENSG00000155363 E042 0.0000000       1 112697860 112697890 31 +      
ENSG00000155363 E043 262.5102470 0.0007654957 1.743650e-01 2.938586e-01 1 112697994 112698111 118 + 2.333 2.379 0.154
ENSG00000155363 E044 158.8748994 0.0022684699 8.926680e-01 9.354193e-01 1 112698287 112698307 21 + 2.139 2.154 0.052
ENSG00000155363 E045 225.1811202 0.0035710709 8.323580e-01 8.949563e-01 1 112698308 112698367 60 + 2.288 2.308 0.068
ENSG00000155363 E046 314.7175291 0.0007284553 2.789746e-02 6.780799e-02 1 112698368 112698478 111 + 2.398 2.464 0.217
ENSG00000155363 E047 19.4958143 0.0275734610 7.810135e-03 2.330236e-02 1 112698479 112698637 159 + 1.446 1.164 -0.989
ENSG00000155363 E048 12.9774275 0.0013542384 3.763771e-03 1.247896e-02 1 112698638 112698656 19 + 1.274 1.010 -0.946
ENSG00000155363 E049 19.3850360 0.0010533211 3.200581e-04 1.461132e-03 1 112698657 112698714 58 + 1.446 1.172 -0.959
ENSG00000155363 E050 294.1384151 0.0015402831 1.668044e-01 2.840223e-01 1 112698715 112698789 75 + 2.381 2.432 0.170
ENSG00000155363 E051 9.8747623 0.0092336869 3.823059e-06 2.793809e-05 1 112698790 112699213 424 + 1.285 0.783 -1.851
ENSG00000155363 E052 6.9613297 0.0024826878 1.174187e-02 3.291743e-02 1 112699214 112699404 191 + 1.046 0.750 -1.128
ENSG00000155363 E053 5.9908166 0.0038242582 4.531998e-03 1.463319e-02 1 112699405 112699457 53 + 1.026 0.676 -1.363
ENSG00000155363 E054 11.8698702 0.0055486189 7.436491e-04 3.056143e-03 1 112699458 112699612 155 + 1.274 0.940 -1.206
ENSG00000155363 E055 5.3673913 0.0062497348 1.772654e-02 4.654333e-02 1 112699613 112699662 50 + 0.963 0.655 -1.216
ENSG00000155363 E056 5.4197925 0.0030106949 1.935732e-03 7.026876e-03 1 112699663 112699684 22 + 1.006 0.611 -1.569
ENSG00000155363 E057 151.5421672 0.0002574127 4.024667e-02 9.148581e-02 1 112699685 112699686 2 + 2.077 2.152 0.251
ENSG00000155363 E058 340.6547431 0.0022568215 3.041785e-04 1.396378e-03 1 112699687 112699810 124 + 2.391 2.514 0.412
ENSG00000155363 E059 3.7727573 0.0055009429 5.972076e-01 7.190059e-01 1 112699811 112699893 83 + 0.686 0.611 -0.321
ENSG00000155363 E060 309.1619226 0.0054310807 2.299976e-04 1.091771e-03 1 112699894 112699982 89 + 2.315 2.483 0.560
ENSG00000155363 E061 39.5447485 0.0005995836 4.348203e-04 1.908517e-03 1 112699983 112700218 236 + 1.691 1.496 -0.664
ENSG00000155363 E062 377.2444760 0.0007932396 6.042400e-15 2.055143e-13 1 112700219 112700310 92 + 2.370 2.575 0.683
ENSG00000155363 E063 253.1441980 0.0002165023 3.617760e-17 1.640043e-15 1 112700311 112700340 30 + 2.170 2.406 0.791
ENSG00000155363 E064 2.6185769 0.0071905473 2.132282e-01 3.423459e-01 1 112700341 112700395 55 + 0.640 0.442 -0.934
ENSG00000155363 E065 2.4733765 0.2207116583 9.450548e-01 9.695432e-01 1 112700396 112700415 20 + 0.466 0.493 0.132
ENSG00000155363 E066 522.5030695 0.0030505733 9.953822e-10 1.477028e-08 1 112700416 112700756 341 + 2.512 2.717 0.681