ENSG00000155229

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000327238 ENSG00000155229 HEK293_OSMI2_2hA HEK293_TMG_2hB MMS19 protein_coding protein_coding 58.27422 87.13238 32.30682 3.26768 1.650372 -1.431089 2.901351 5.104496 1.7115396 0.3762499 0.4196178 -1.5708927 0.05017917 0.05856667 0.05200000 -0.006566667 8.395967e-01 1.348824e-08 FALSE TRUE
ENST00000370782 ENSG00000155229 HEK293_OSMI2_2hA HEK293_TMG_2hB MMS19 protein_coding protein_coding 58.27422 87.13238 32.30682 3.26768 1.650372 -1.431089 22.725334 28.158446 14.4735782 3.0645638 1.1290430 -0.9596619 0.41220833 0.32353333 0.45246667 0.128933333 2.475257e-01 1.348824e-08 FALSE TRUE
ENST00000434538 ENSG00000155229 HEK293_OSMI2_2hA HEK293_TMG_2hB MMS19 protein_coding protein_coding 58.27422 87.13238 32.30682 3.26768 1.650372 -1.431089 3.819053 8.443790 1.0517722 2.1945255 0.3485446 -2.9931240 0.05382083 0.09730000 0.03166667 -0.065633333 9.093180e-02 1.348824e-08 FALSE TRUE
ENST00000438925 ENSG00000155229 HEK293_OSMI2_2hA HEK293_TMG_2hB MMS19 protein_coding protein_coding 58.27422 87.13238 32.30682 3.26768 1.650372 -1.431089 3.987447 8.917084 0.4687649 1.5026226 0.4687649 -4.2207999 0.05277083 0.10143333 0.01326667 -0.088166667 6.371160e-02 1.348824e-08 FALSE TRUE
ENST00000444411 ENSG00000155229 HEK293_OSMI2_2hA HEK293_TMG_2hB MMS19 protein_coding protein_coding 58.27422 87.13238 32.30682 3.26768 1.650372 -1.431089 7.581408 20.924445 1.3471438 1.7876263 0.4176338 -3.9472332 0.10222500 0.24113333 0.04113333 -0.200000000 1.144456e-05 1.348824e-08   FALSE
ENST00000477575 ENSG00000155229 HEK293_OSMI2_2hA HEK293_TMG_2hB MMS19 protein_coding retained_intron 58.27422 87.13238 32.30682 3.26768 1.650372 -1.431089 3.194604 1.186271 2.7065737 0.2448293 0.3328912 1.1832436 0.06649167 0.01346667 0.08443333 0.070966667 1.348824e-08 1.348824e-08 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000155229 E001 5.369463 0.0031805265 7.004870e-01 7.999491e-01 10 97457734 97458089 356 - 0.774 0.719 -0.223
ENSG00000155229 E002 3.933156 0.0046631120 4.256039e-01 5.685372e-01 10 97458090 97458230 141 - 0.732 0.611 -0.515
ENSG00000155229 E003 3.706513 0.0045625454 5.423169e-01 6.730979e-01 10 97458231 97458300 70 - 0.686 0.590 -0.414
ENSG00000155229 E004 2.531517 0.0086413807 2.409023e-01 3.752341e-01 10 97458301 97458323 23 - 0.322 0.544 1.185
ENSG00000155229 E005 5.481874 0.0166940471 8.126651e-04 3.304294e-03 10 97458324 97458325 2 - 0.190 0.841 3.432
ENSG00000155229 E006 642.799916 0.0030913001 9.058705e-07 7.591544e-06 10 97458326 97458648 323 - 2.601 2.761 0.533
ENSG00000155229 E007 432.596523 0.0017577363 1.684874e-07 1.638407e-06 10 97458649 97458719 71 - 2.432 2.588 0.521
ENSG00000155229 E008 477.921469 0.0032430150 3.869460e-03 1.277594e-02 10 97458800 97458900 101 - 2.521 2.622 0.336
ENSG00000155229 E009 377.832440 0.0027319709 7.612340e-04 3.119681e-03 10 97459223 97459282 60 - 2.405 2.522 0.393
ENSG00000155229 E010 504.064786 0.0027110137 2.846975e-03 9.814767e-03 10 97459362 97459505 144 - 2.546 2.644 0.326
ENSG00000155229 E011 218.885052 0.0002716076 1.796711e-03 6.588878e-03 10 97459506 97459526 21 - 2.187 2.281 0.313
ENSG00000155229 E012 13.548179 0.0013730875 4.701113e-08 5.099117e-07 10 97459527 97459658 132 - 1.411 0.910 -1.795
ENSG00000155229 E013 394.707575 0.0001719457 8.649436e-04 3.490786e-03 10 97459659 97459741 83 - 2.458 2.532 0.247
ENSG00000155229 E014 13.923945 0.0030787520 3.472550e-07 3.171347e-06 10 97459742 97460045 304 - 1.411 0.940 -1.683
ENSG00000155229 E015 253.919613 0.0001827416 1.750594e-02 4.605667e-02 10 97460046 97460072 27 - 2.273 2.338 0.217
ENSG00000155229 E016 471.848964 0.0001461630 1.013748e-06 8.398269e-06 10 97460073 97460232 160 - 2.514 2.614 0.333
ENSG00000155229 E017 5.909821 0.0106925306 6.670624e-02 1.379196e-01 10 97460233 97460319 87 - 0.940 0.687 -0.993
ENSG00000155229 E018 297.473257 0.0008502176 1.959574e-04 9.466188e-04 10 97460695 97460751 57 - 2.309 2.417 0.360
ENSG00000155229 E019 319.563100 0.0006995755 3.981371e-06 2.898153e-05 10 97460907 97461007 101 - 2.323 2.451 0.426
ENSG00000155229 E020 12.492179 0.0076286628 5.954117e-07 5.190694e-06 10 97461008 97461366 359 - 1.382 0.879 -1.816
ENSG00000155229 E021 303.330017 0.0001654885 3.869503e-10 6.187253e-09 10 97461496 97461588 93 - 2.270 2.433 0.542
ENSG00000155229 E022 266.550748 0.0006442994 2.307243e-04 1.094694e-03 10 97461589 97461622 34 - 2.261 2.369 0.360
ENSG00000155229 E023 17.170712 0.0010782097 5.410973e-05 3.022802e-04 10 97461623 97461827 205 - 1.420 1.079 -1.204
ENSG00000155229 E024 316.435241 0.0002408461 2.702786e-02 6.605450e-02 10 97461828 97461896 69 - 2.378 2.433 0.184
ENSG00000155229 E025 396.864799 0.0001877375 1.389764e-01 2.466893e-01 10 97462017 97462119 103 - 2.493 2.526 0.110
ENSG00000155229 E026 378.277808 0.0001908326 8.298558e-01 8.931850e-01 10 97462583 97462682 100 - 2.494 2.499 0.019
ENSG00000155229 E027 1.953082 0.0072099914 7.888051e-02 1.577252e-01 10 97462683 97463006 324 - 0.633 0.334 -1.514
ENSG00000155229 E028 372.876068 0.0003054604 6.126554e-01 7.315328e-01 10 97463858 97464013 156 - 2.482 2.495 0.042
ENSG00000155229 E029 236.256104 0.0003163162 4.136843e-01 5.571007e-01 10 97465805 97465864 60 - 2.311 2.289 -0.072
ENSG00000155229 E030 320.783999 0.0045935304 6.698083e-01 7.764565e-01 10 97465865 97465954 90 - 2.440 2.425 -0.050
ENSG00000155229 E031 325.193341 0.0014167406 6.109208e-01 7.301668e-01 10 97466059 97466156 98 - 2.442 2.429 -0.041
ENSG00000155229 E032 153.815008 0.0002557107 6.138285e-01 7.324535e-01 10 97466157 97466159 3 - 2.120 2.104 -0.054
ENSG00000155229 E033 276.563877 0.0002113558 8.162622e-01 8.837360e-01 10 97466504 97466585 82 - 2.364 2.359 -0.017
ENSG00000155229 E034 314.908561 0.0001757971 5.056270e-01 6.413761e-01 10 97466776 97466901 126 - 2.428 2.413 -0.050
ENSG00000155229 E035 271.547077 0.0031253206 2.274566e-01 3.593670e-01 10 97467505 97467583 79 - 2.386 2.345 -0.138
ENSG00000155229 E036 7.262144 0.0022249209 2.502099e-04 1.176100e-03 10 97467584 97467603 20 - 1.135 0.703 -1.644
ENSG00000155229 E037 359.593474 0.0022242041 1.440087e-02 3.913588e-02 10 97468252 97468406 155 - 2.529 2.458 -0.237
ENSG00000155229 E038 307.524676 0.0017991013 6.514430e-02 1.352748e-01 10 97468966 97469094 129 - 2.447 2.394 -0.176
ENSG00000155229 E039 162.905765 0.0002486680 1.179253e-01 2.169597e-01 10 97469095 97469104 10 - 2.170 2.120 -0.166
ENSG00000155229 E040 10.332251 0.0017870221 7.758051e-10 1.174758e-08 10 97469105 97469126 22 - 1.362 0.735 -2.310
ENSG00000155229 E041 170.253841 0.0002297008 3.012453e-03 1.030275e-02 10 97469646 97469652 7 - 2.220 2.129 -0.305
ENSG00000155229 E042 186.417159 0.0002046854 3.357296e-03 1.131323e-02 10 97469653 97469672 20 - 2.256 2.170 -0.288
ENSG00000155229 E043 237.230381 0.0001693784 2.281891e-03 8.095911e-03 10 97469673 97469723 51 - 2.355 2.275 -0.266
ENSG00000155229 E044 277.921198 0.0009807147 7.603517e-05 4.092342e-04 10 97470129 97470203 75 - 2.446 2.338 -0.360
ENSG00000155229 E045 238.175763 0.0046943347 4.215187e-02 9.500472e-02 10 97470775 97470830 56 - 2.361 2.280 -0.272
ENSG00000155229 E046 155.628798 0.0041594547 2.036782e-01 3.308061e-01 10 97470831 97470834 4 - 2.157 2.103 -0.179
ENSG00000155229 E047 188.360060 0.0042864829 1.167162e-01 2.152729e-01 10 97470835 97470861 27 - 2.247 2.183 -0.214
ENSG00000155229 E048 188.240437 0.0053459786 5.081963e-02 1.106357e-01 10 97476683 97476728 46 - 2.262 2.177 -0.286
ENSG00000155229 E049 153.967382 0.0031107549 3.299300e-02 7.779020e-02 10 97476729 97476744 16 - 2.174 2.088 -0.288
ENSG00000155229 E050 241.773255 0.0043671712 9.159824e-02 1.776280e-01 10 97476835 97476916 82 - 2.355 2.290 -0.216
ENSG00000155229 E051 128.837640 0.0036101730 1.682658e-01 2.859425e-01 10 97476917 97476919 3 - 2.078 2.018 -0.200
ENSG00000155229 E052 221.972751 0.0039324371 3.551903e-01 4.995637e-01 10 97476920 97476963 44 - 2.294 2.260 -0.111
ENSG00000155229 E053 30.156192 0.0034406367 1.964333e-25 2.241789e-23 10 97476964 97477346 383 - 1.837 1.126 -2.453
ENSG00000155229 E054 278.974964 0.0007941728 8.325717e-05 4.434305e-04 10 97477347 97477404 58 - 2.443 2.338 -0.349
ENSG00000155229 E055 171.136557 0.0002235033 8.850551e-05 4.680019e-04 10 97477405 97477416 12 - 2.242 2.123 -0.398
ENSG00000155229 E056 249.705138 0.0003384637 9.991579e-06 6.640967e-05 10 97477855 97477929 75 - 2.403 2.288 -0.382
ENSG00000155229 E057 263.401088 0.0033598954 2.114748e-03 7.580276e-03 10 97478304 97478389 86 - 2.423 2.314 -0.362
ENSG00000155229 E058 6.872263 0.0025242451 9.665930e-01 9.830475e-01 10 97480241 97480357 117 - 0.813 0.819 0.024
ENSG00000155229 E059 1.067386 0.0135198173 6.915797e-01 7.930232e-01 10 97480895 97480941 47 - 0.322 0.248 -0.511
ENSG00000155229 E060 254.229713 0.0026355964 7.481535e-04 3.072122e-03 10 97480942 97481042 101 - 2.411 2.298 -0.379
ENSG00000155229 E061 145.806564 0.0043217550 1.596270e-02 4.264681e-02 10 97484103 97484151 49 - 2.165 2.059 -0.354
ENSG00000155229 E062 156.654372 0.0102519234 2.722891e-02 6.645500e-02 10 97498273 97498392 120 - 2.213 2.086 -0.424
ENSG00000155229 E063 36.541589 0.0086912291 4.423416e-01 5.839713e-01 10 97498393 97498609 217 - 1.538 1.479 -0.205
ENSG00000155229 E064 4.028446 0.0079074883 5.694529e-02 1.213648e-01 10 97498696 97498796 101 - 0.848 0.567 -1.168