ENSG00000155096

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000337198 ENSG00000155096 HEK293_OSMI2_2hA HEK293_TMG_2hB AZIN1 protein_coding protein_coding 45.82282 18.70992 71.76731 1.538113 2.289899 1.938954 17.739142 11.396074 27.42951 1.90712632 1.3451745 1.266453 0.4483708 0.6027333 0.3820000 -0.22073333 1.557293e-02 5.044066e-39 FALSE TRUE
ENST00000347770 ENSG00000155096 HEK293_OSMI2_2hA HEK293_TMG_2hB AZIN1 protein_coding protein_coding 45.82282 18.70992 71.76731 1.538113 2.289899 1.938954 16.184122 4.919816 26.26059 0.09807712 1.4514468 2.413843 0.3336458 0.2666000 0.3653667 0.09876667 2.970947e-02 5.044066e-39 FALSE TRUE
MSTRG.31943.13 ENSG00000155096 HEK293_OSMI2_2hA HEK293_TMG_2hB AZIN1 protein_coding   45.82282 18.70992 71.76731 1.538113 2.289899 1.938954 7.890651 0.000000 12.13100 0.00000000 0.5157533 10.245671 0.1239875 0.0000000 0.1695667 0.16956667 5.044066e-39 5.044066e-39 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000155096 E001 2.3219919 0.0345517862 3.914761e-01 5.353910e-01 8 102826111 102826307 197 - 0.425 0.590 0.801
ENSG00000155096 E002 3.5594647 0.1803467396 3.167485e-03 1.075993e-02 8 102826308 102826367 60 - 0.323 0.969 2.911
ENSG00000155096 E003 3.6357372 0.1676201503 9.319735e-04 3.726301e-03 8 102826368 102826371 4 - 0.284 0.998 3.279
ENSG00000155096 E004 3.6357372 0.1676201503 9.319735e-04 3.726301e-03 8 102826372 102826378 7 - 0.284 0.998 3.279
ENSG00000155096 E005 16.7147689 0.0025880675 1.672949e-14 5.341903e-13 8 102826379 102826439 61 - 0.903 1.577 2.390
ENSG00000155096 E006 33.4784258 0.0255011522 1.090219e-13 3.081747e-12 8 102826440 102826480 41 - 1.125 1.897 2.657
ENSG00000155096 E007 93.3150318 0.0101788091 7.612869e-13 1.904947e-11 8 102826481 102826590 110 - 1.744 2.216 1.588
ENSG00000155096 E008 745.8350816 0.0037139318 3.865215e-09 5.140424e-08 8 102826591 102827822 1232 - 2.761 2.965 0.677
ENSG00000155096 E009 824.6571947 0.0003659088 1.117442e-18 6.130785e-17 8 102827823 102828546 724 - 2.824 2.978 0.513
ENSG00000155096 E010 202.5134125 0.0007326433 4.410163e-05 2.518211e-04 8 102828547 102828589 43 - 2.219 2.359 0.468
ENSG00000155096 E011 280.6992564 0.0001957866 5.204337e-06 3.688675e-05 8 102828590 102828678 89 - 2.365 2.492 0.425
ENSG00000155096 E012 470.6607012 0.0001625695 5.135342e-03 1.629688e-02 8 102829272 102829455 184 - 2.608 2.681 0.243
ENSG00000155096 E013 262.4481811 0.0007527816 3.338126e-01 4.775626e-01 8 102829456 102829486 31 - 2.364 2.411 0.158
ENSG00000155096 E014 359.0824788 0.0001873930 8.850382e-01 9.305109e-01 8 102829821 102829933 113 - 2.506 2.531 0.084
ENSG00000155096 E015 143.9734083 0.0002654676 5.932180e-01 7.156538e-01 8 102829934 102829936 3 - 2.118 2.122 0.015
ENSG00000155096 E016 1.6126155 0.3602730719 6.128113e-01 7.316729e-01 8 102830126 102830221 96 - 0.323 0.522 1.072
ENSG00000155096 E017 0.6966286 0.6589116134 2.138151e-01 3.430265e-01 8 102830222 102830227 6 - 0.074 0.439 3.237
ENSG00000155096 E018 368.7456924 0.0001598964 8.817443e-01 9.282172e-01 8 102833056 102833218 163 - 2.517 2.542 0.083
ENSG00000155096 E019 272.6603592 0.0001880446 3.378749e-02 7.932950e-02 8 102834189 102834234 46 - 2.401 2.370 -0.103
ENSG00000155096 E020 242.5869856 0.0002060649 1.025390e-03 4.046096e-03 8 102834235 102834260 26 - 2.359 2.293 -0.220
ENSG00000155096 E021 192.3888735 0.0002009014 5.701361e-03 1.782029e-02 8 102834261 102834263 3 - 2.257 2.197 -0.202
ENSG00000155096 E022 289.3675776 0.0001536903 4.799089e-02 1.056210e-01 8 102834666 102834747 82 - 2.425 2.399 -0.085
ENSG00000155096 E023 8.8169374 0.0105183534 3.572848e-02 8.306083e-02 8 102834748 102835475 728 - 1.017 0.747 -1.038
ENSG00000155096 E024 380.3291798 0.0001386285 4.470504e-06 3.218895e-05 8 102836256 102836390 135 - 2.556 2.481 -0.251
ENSG00000155096 E025 18.0290996 0.0014997757 4.598154e-01 5.999031e-01 8 102836391 102836541 151 - 1.250 1.202 -0.167
ENSG00000155096 E026 399.4099608 0.0001402297 8.688843e-09 1.083230e-07 8 102838744 102838901 158 - 2.584 2.486 -0.327
ENSG00000155096 E027 151.1355762 0.0012465507 5.221697e-03 1.653465e-02 8 102838902 102838916 15 - 2.159 2.074 -0.284
ENSG00000155096 E028 385.5316253 0.0015159741 9.469320e-05 4.970862e-04 8 102839650 102839823 174 - 2.565 2.473 -0.307
ENSG00000155096 E029 181.3800414 0.0003810020 2.059824e-05 1.274004e-04 8 102843551 102843553 3 - 2.243 2.128 -0.384
ENSG00000155096 E030 405.7548340 0.0001946612 1.135008e-11 2.342052e-10 8 102843554 102843729 176 - 2.595 2.472 -0.410
ENSG00000155096 E031 160.4324442 0.0001982920 1.765210e-08 2.079429e-07 8 102843730 102843747 18 - 2.205 2.037 -0.561
ENSG00000155096 E032 4.3556313 0.0043264297 6.470303e-01 7.587852e-01 8 102849987 102849998 12 - 0.704 0.648 -0.234
ENSG00000155096 E033 87.5098126 0.0003042713 2.520649e-06 1.918559e-05 8 102849999 102850144 146 - 1.948 1.754 -0.655
ENSG00000155096 E034 1.3424206 0.0160061472 4.646276e-02 1.028729e-01 8 102850145 102850165 21 - 0.425 0.000 -11.009
ENSG00000155096 E035 327.5549973 0.0001530508 3.567149e-16 1.429024e-14 8 102858013 102858150 138 - 2.512 2.340 -0.574
ENSG00000155096 E036 0.4439371 0.0215792914 4.387990e-01 5.806488e-01 8 102859070 102859188 119 - 0.191 0.000 -9.423
ENSG00000155096 E037 219.9101455 0.0012405056 1.567145e-11 3.160095e-10 8 102863807 102863882 76 - 2.347 2.140 -0.692
ENSG00000155096 E038 253.6228654 0.0086429063 1.342807e-03 5.119081e-03 8 102863883 102864193 311 - 2.397 2.240 -0.524
ENSG00000155096 E039 0.0000000       8 102872277 102872412 136 -      
ENSG00000155096 E040 0.0000000       8 102886918 102887147 230 -      
ENSG00000155096 E041 0.0000000       8 102893803 102893864 62 -