ENSG00000152782

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000307534 ENSG00000152782 HEK293_OSMI2_2hA HEK293_TMG_2hB PANK1 protein_coding protein_coding 10.46973 9.086759 14.00726 0.5427456 0.2138116 0.6237793 4.6139142 3.13853121 7.0854326 0.35849289 0.7391203 1.17221168 0.43898333 0.3522000 0.50736667 0.15516667 0.30491452 0.04655673 FALSE  
ENST00000342512 ENSG00000152782 HEK293_OSMI2_2hA HEK293_TMG_2hB PANK1 protein_coding protein_coding 10.46973 9.086759 14.00726 0.5427456 0.2138116 0.6237793 2.5195500 2.11045800 2.5388570 0.69959459 0.8947105 0.26547452 0.21904583 0.2271333 0.18016667 -0.04696667 0.85758853 0.04655673 FALSE  
ENST00000461829 ENSG00000152782 HEK293_OSMI2_2hA HEK293_TMG_2hB PANK1 protein_coding processed_transcript 10.46973 9.086759 14.00726 0.5427456 0.2138116 0.6237793 0.4950232 0.09140183 0.9718107 0.04723016 0.3803849 3.27536110 0.04513333 0.0096000 0.06933333 0.05973333 0.04655673 0.04655673 FALSE  
MSTRG.4348.7 ENSG00000152782 HEK293_OSMI2_2hA HEK293_TMG_2hB PANK1 protein_coding   10.46973 9.086759 14.00726 0.5427456 0.2138116 0.6237793 1.1562846 1.55522384 1.2270971 0.92284635 0.1205530 -0.33941025 0.11573333 0.1677333 0.08756667 -0.08016667 0.99781916 0.04655673    
MSTRG.4348.8 ENSG00000152782 HEK293_OSMI2_2hA HEK293_TMG_2hB PANK1 protein_coding   10.46973 9.086759 14.00726 0.5427456 0.2138116 0.6237793 1.1096800 1.47051031 1.5522454 0.06220088 0.1598901 0.07752658 0.11649167 0.1626000 0.11063333 -0.05196667 0.13642417 0.04655673 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000152782 E001 274.313121 0.0013753652 6.901648e-13 1.738923e-11 10 89582988 89584183 1196 - 2.360 2.525 0.553
ENSG00000152782 E002 94.627428 0.0040344689 1.083311e-01 2.030734e-01 10 89584184 89584465 282 - 2.010 1.944 -0.220
ENSG00000152782 E003 70.832116 0.0004478254 1.752508e-04 8.579666e-04 10 89588652 89588777 126 - 1.917 1.763 -0.517
ENSG00000152782 E004 74.859444 0.0003788698 2.331722e-04 1.104814e-03 10 89593197 89593320 124 - 1.938 1.793 -0.488
ENSG00000152782 E005 87.007272 0.0049629926 1.199006e-02 3.350811e-02 10 89593813 89593989 177 - 1.992 1.875 -0.395
ENSG00000152782 E006 1.699372 0.0079583164 8.591013e-01 9.130822e-01 10 89599162 89599251 90 - 0.448 0.422 -0.140
ENSG00000152782 E007 101.053140 0.0018190401 1.142445e-03 4.445856e-03 10 89599252 89599505 254 - 2.058 1.937 -0.407
ENSG00000152782 E008 87.902416 0.0074053064 5.910324e-05 3.270323e-04 10 89611696 89612048 353 - 2.029 1.808 -0.742
ENSG00000152782 E009 1.310629 0.5991696034 4.052450e-01 5.489298e-01 10 89625695 89625753 59 - 0.248 0.483 1.406
ENSG00000152782 E010 9.373607 0.0443675328 3.690007e-04 1.654190e-03 10 89625754 89625853 100 - 0.731 1.228 1.861
ENSG00000152782 E011 8.692027 0.0500944350 3.353208e-04 1.521715e-03 10 89626193 89626249 57 - 0.664 1.195 2.020
ENSG00000152782 E012 8.755430 0.0034865960 4.625814e-04 2.016491e-03 10 89626537 89626632 96 - 0.771 1.163 1.466
ENSG00000152782 E013 39.865208 0.0021776543 5.669345e-05 3.150695e-04 10 89634777 89635065 289 - 1.491 1.725 0.799
ENSG00000152782 E014 5.398134 0.0215441499 2.269926e-01 3.588089e-01 10 89643697 89643956 260 - 0.710 0.881 0.676
ENSG00000152782 E015 54.355089 0.0103270291 6.280607e-01 7.437044e-01 10 89644600 89644693 94 - 1.726 1.753 0.091
ENSG00000152782 E016 34.295225 0.0126937815 9.596141e-01 9.786291e-01 10 89644694 89644774 81 - 1.539 1.542 0.011
ENSG00000152782 E017 37.589535 0.0045608393 7.904857e-01 8.659871e-01 10 89644775 89645242 468 - 1.590 1.574 -0.056
ENSG00000152782 E018 0.000000       10 89645491 89645509 19 -