ENSG00000152102

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000389915 ENSG00000152102 HEK293_OSMI2_2hA HEK293_TMG_2hB FAM168B protein_coding protein_coding 49.04473 43.73571 59.20254 5.408837 0.7039115 0.436761 24.80121 17.321708 37.703584 1.4464798 0.3984728 1.1216705 0.49485000 0.41140000 0.63686667 0.2254667 0.03377414 0.00725887 FALSE TRUE
ENST00000409185 ENSG00000152102 HEK293_OSMI2_2hA HEK293_TMG_2hB FAM168B protein_coding protein_coding 49.04473 43.73571 59.20254 5.408837 0.7039115 0.436761 19.58951 23.437970 15.059994 6.3344689 0.8253134 -0.6377841 0.41283750 0.51973333 0.25426667 -0.2654667 0.01296712 0.00725887 FALSE TRUE
MSTRG.19213.1 ENSG00000152102 HEK293_OSMI2_2hA HEK293_TMG_2hB FAM168B protein_coding   49.04473 43.73571 59.20254 5.408837 0.7039115 0.436761 3.56760 2.561791 4.846159 0.4537744 0.4055581 0.9170421 0.07183333 0.05913333 0.08183333 0.0227000 0.38565142 0.00725887 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000152102 E001 0.000000       2 131047830 131047875 46 -      
ENSG00000152102 E002 6182.917257 0.007569468 2.396610e-09 3.312399e-08 2 131047876 131051999 4124 - 3.668 3.913 0.814
ENSG00000152102 E003 240.939135 0.005015201 3.346919e-06 2.480590e-05 2 131052000 131052071 72 - 2.385 2.360 -0.082
ENSG00000152102 E004 127.999563 0.008058266 4.555552e-04 1.988832e-03 2 131052072 131052080 9 - 2.111 2.089 -0.072
ENSG00000152102 E005 551.866795 0.001018506 7.697031e-22 6.010633e-20 2 131052081 131052452 372 - 2.746 2.717 -0.097
ENSG00000152102 E006 264.074324 0.002081141 5.550598e-06 3.910976e-05 2 131052891 131053015 125 - 2.403 2.437 0.113
ENSG00000152102 E007 323.997722 0.002914918 1.376014e-10 2.372638e-09 2 131055272 131055449 178 - 2.519 2.481 -0.128
ENSG00000152102 E008 274.161561 0.005017122 2.024518e-06 1.573299e-05 2 131055553 131055695 143 - 2.440 2.416 -0.082
ENSG00000152102 E009 192.039268 0.008502433 8.029278e-04 3.269607e-03 2 131071855 131071938 84 - 2.280 2.270 -0.033
ENSG00000152102 E010 3.211650 0.004952409 3.818157e-01 5.260911e-01 2 131072022 131072050 29 - 0.499 0.769 1.178
ENSG00000152102 E011 154.132644 0.013613888 1.655040e-02 4.394919e-02 2 131082577 131082657 81 - 2.177 2.186 0.029
ENSG00000152102 E012 4.783366 0.003472379 3.718876e-01 5.163661e-01 2 131088963 131089042 80 - 0.638 0.907 1.081
ENSG00000152102 E013 6.474521 0.006610723 7.776185e-01 8.569055e-01 2 131089043 131089121 79 - 0.813 0.931 0.455
ENSG00000152102 E014 30.312102 0.002924901 2.036746e-02 5.225845e-02 2 131091809 131091963 155 - 1.483 1.499 0.054
ENSG00000152102 E015 1.333786 0.023892337 1.631242e-01 2.792240e-01 2 131093014 131093213 200 - 0.427 0.275 -0.922
ENSG00000152102 E016 109.447740 0.009487826 3.707338e-05 2.153901e-04 2 131093214 131093310 97 - 2.063 1.984 -0.266
ENSG00000152102 E017 51.079456 0.008033556 1.206871e-04 6.171234e-04 2 131093311 131093331 21 - 1.741 1.652 -0.301
ENSG00000152102 E018 65.925560 0.009822790 1.572721e-10 2.683243e-09 2 131093332 131093465 134 - 1.903 1.631 -0.917