ENSG00000151779

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000281513 ENSG00000151779 HEK293_OSMI2_2hA HEK293_TMG_2hB NBAS protein_coding protein_coding 9.045853 8.886961 8.795796 2.143965 0.550593 -0.01485921 4.1687109 1.2158038 6.7403296 0.3512536 0.13566484 2.461230 0.4597958 0.14126667 0.77040000 0.62913333 7.758953e-14 7.758953e-14 FALSE TRUE
ENST00000417461 ENSG00000151779 HEK293_OSMI2_2hA HEK293_TMG_2hB NBAS protein_coding protein_coding 9.045853 8.886961 8.795796 2.143965 0.550593 -0.01485921 0.9781249 2.6819971 0.1062884 1.1444279 0.05624711 -4.532898 0.1041833 0.30150000 0.01170000 -0.28980000 1.145035e-04 7.758953e-14 TRUE TRUE
ENST00000433283 ENSG00000151779 HEK293_OSMI2_2hA HEK293_TMG_2hB NBAS protein_coding protein_coding 9.045853 8.886961 8.795796 2.143965 0.550593 -0.01485921 1.4180093 1.7372661 0.6114797 0.5692796 0.48429208 -1.491320 0.1536708 0.18793333 0.06346667 -0.12446667 3.082664e-01 7.758953e-14 FALSE TRUE
ENST00000442506 ENSG00000151779 HEK293_OSMI2_2hA HEK293_TMG_2hB NBAS protein_coding protein_coding 9.045853 8.886961 8.795796 2.143965 0.550593 -0.01485921 1.4447500 2.5057560 0.1990336 0.4955134 0.19903364 -3.589185 0.1651917 0.29046667 0.02453333 -0.26593333 2.361818e-02 7.758953e-14 FALSE TRUE
MSTRG.17988.5 ENSG00000151779 HEK293_OSMI2_2hA HEK293_TMG_2hB NBAS protein_coding   9.045853 8.886961 8.795796 2.143965 0.550593 -0.01485921 0.9419858 0.6572451 1.0863654 0.2436828 0.13899040 0.716440 0.1065625 0.06876667 0.12463333 0.05586667 2.922131e-01 7.758953e-14 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000151779 E001 0.1817044 0.0401735750 2.690285e-01   2 15166914 15166915 2 - 0.000 0.162 11.111
ENSG00000151779 E002 0.3332198 0.0302898242 6.688582e-01   2 15166916 15166916 1 - 0.091 0.162 0.958
ENSG00000151779 E003 103.0344829 0.0203423218 4.255157e-11 7.990155e-10 2 15166917 15167323 407 - 1.727 2.257 1.778
ENSG00000151779 E004 0.4031496 0.0339728730 8.281078e-02 1.639487e-01 2 15177949 15178157 209 - 0.000 0.281 12.150
ENSG00000151779 E005 61.5764680 0.0454786997 1.350936e-05 8.706607e-05 2 15178988 15179116 129 - 1.512 2.032 1.757
ENSG00000151779 E006 1.1749062 0.0113251185 7.131484e-03 2.156531e-02 2 15179117 15180378 1262 - 0.091 0.570 3.542
ENSG00000151779 E007 77.8170861 0.0013586627 2.555256e-13 6.859429e-12 2 15186742 15186880 139 - 1.731 2.078 1.168
ENSG00000151779 E008 84.3573504 0.0007145059 4.429474e-11 8.292001e-10 2 15190264 15190403 140 - 1.794 2.087 0.986
ENSG00000151779 E009 85.7883272 0.0098847122 3.148929e-06 2.344489e-05 2 15218773 15218968 196 - 1.788 2.096 1.035
ENSG00000151779 E010 57.2141945 0.0046734650 3.750221e-10 6.009711e-09 2 15232422 15232511 90 - 1.573 1.961 1.311
ENSG00000151779 E011 85.9955562 0.0061770873 1.944574e-12 4.544704e-11 2 15234545 15234747 203 - 1.730 2.146 1.397
ENSG00000151779 E012 95.1009886 0.0022776469 2.004517e-09 2.805243e-08 2 15238468 15238686 219 - 1.849 2.137 0.966
ENSG00000151779 E013 112.6269716 0.0002536707 4.357859e-05 2.490735e-04 2 15275484 15275818 335 - 1.978 2.149 0.573
ENSG00000151779 E014 82.5210419 0.0003206874 5.762403e-02 1.225480e-01 2 15276851 15277101 251 - 1.871 1.981 0.369
ENSG00000151779 E015 54.5882037 0.0004069233 7.429880e-01 8.317616e-01 2 15287073 15287183 111 - 1.719 1.771 0.176
ENSG00000151779 E016 72.3749171 0.0004302233 1.065496e-01 2.004654e-01 2 15292537 15292766 230 - 1.822 1.926 0.350
ENSG00000151779 E017 44.1238437 0.0134441245 7.237573e-01 8.175006e-01 2 15308216 15308353 138 - 1.625 1.687 0.210
ENSG00000151779 E018 32.5829135 0.0007839809 4.265649e-01 5.693815e-01 2 15309171 15309247 77 - 1.487 1.571 0.290
ENSG00000151779 E019 40.9569505 0.0005792087 7.796798e-01 8.583682e-01 2 15327750 15327870 121 - 1.597 1.648 0.175
ENSG00000151779 E020 42.7697264 0.0008948859 1.736122e-01 2.928832e-01 2 15328199 15328312 114 - 1.648 1.607 -0.139
ENSG00000151779 E021 47.2376050 0.0355327981 4.451251e-01 5.866799e-01 2 15330598 15330765 168 - 1.691 1.638 -0.180
ENSG00000151779 E022 33.9506972 0.0006190005 1.329174e-01 2.381704e-01 2 15351992 15352081 90 - 1.559 1.503 -0.194
ENSG00000151779 E023 42.4061182 0.0005164931 9.875356e-02 1.885868e-01 2 15353553 15353710 158 - 1.652 1.597 -0.188
ENSG00000151779 E024 37.9719963 0.0025957116 2.527918e-01 3.892156e-01 2 15356303 15356416 114 - 1.597 1.560 -0.126
ENSG00000151779 E025 38.1603304 0.0033939029 3.721557e-01 5.166158e-01 2 15366580 15366693 114 - 1.592 1.566 -0.088
ENSG00000151779 E026 35.0468140 0.0006255649 4.492052e-02 1.000536e-01 2 15374608 15374720 113 - 1.579 1.490 -0.302
ENSG00000151779 E027 40.4217624 0.0028937661 9.898200e-02 1.889221e-01 2 15379602 15379831 230 - 1.634 1.566 -0.232
ENSG00000151779 E028 28.4783163 0.0247826968 6.203877e-02 1.300520e-01 2 15383215 15383317 103 - 1.512 1.357 -0.536
ENSG00000151779 E029 0.0000000       2 15393639 15393727 89 -      
ENSG00000151779 E030 44.7012685 0.0042637534 7.701157e-04 3.150287e-03 2 15394227 15394349 123 - 1.713 1.537 -0.601
ENSG00000151779 E031 36.8318322 0.0041029575 5.949517e-04 2.514766e-03 2 15396413 15396475 63 - 1.636 1.435 -0.687
ENSG00000151779 E032 44.3092088 0.0005005079 2.105740e-03 7.551843e-03 2 15402168 15402301 134 - 1.695 1.561 -0.458
ENSG00000151779 E033 39.6882103 0.0035431561 5.528414e-02 1.184829e-01 2 15415546 15415719 174 - 1.634 1.544 -0.307
ENSG00000151779 E034 45.5040240 0.0005154139 6.562951e-03 2.009002e-02 2 15417527 15417712 186 - 1.699 1.587 -0.382
ENSG00000151779 E035 50.0027943 0.0006636527 5.758251e-04 2.443735e-03 2 15424315 15424468 154 - 1.749 1.602 -0.499
ENSG00000151779 E036 41.7175067 0.0010060353 1.861886e-05 1.163545e-04 2 15427711 15427794 84 - 1.695 1.477 -0.744
ENSG00000151779 E037 43.0330848 0.0087583261 3.512649e-04 1.585223e-03 2 15461201 15461337 137 - 1.710 1.482 -0.776
ENSG00000151779 E038 25.5286704 0.0007861826 6.692156e-04 2.785720e-03 2 15461687 15461791 105 - 1.486 1.271 -0.746
ENSG00000151779 E039 26.4108707 0.0008045936 3.120261e-06 2.325077e-05 2 15467329 15467407 79 - 1.527 1.215 -1.085
ENSG00000151779 E040 38.6375854 0.0028846957 5.361861e-07 4.714948e-06 2 15467664 15467804 141 - 1.683 1.382 -1.030
ENSG00000151779 E041 31.3674882 0.0137140173 1.388450e-03 5.268869e-03 2 15468382 15468533 152 - 1.583 1.336 -0.851
ENSG00000151779 E042 30.8302337 0.0340746079 8.995180e-04 3.612545e-03 2 15473222 15473347 126 - 1.595 1.250 -1.192
ENSG00000151779 E043 51.8661384 0.0040493429 3.098962e-11 5.955458e-10 2 15474067 15474324 258 - 1.827 1.435 -1.333
ENSG00000151779 E044 37.8463667 0.0069591885 4.126490e-07 3.711666e-06 2 15475687 15475880 194 - 1.685 1.330 -1.219
ENSG00000151779 E045 14.1872488 0.0013616160 1.723082e-03 6.355157e-03 2 15478226 15478244 19 - 1.256 0.983 -0.984
ENSG00000151779 E046 20.8769082 0.0008943662 5.416985e-05 3.025909e-04 2 15478245 15478289 45 - 1.422 1.122 -1.056
ENSG00000151779 E047 0.1515154 0.0470226512 1.000000e+00   2 15483262 15483368 107 - 0.091 0.000 -9.506
ENSG00000151779 E048 25.9091989 0.0007824240 1.821252e-06 1.429646e-05 2 15488894 15489022 129 - 1.518 1.191 -1.140
ENSG00000151779 E049 24.2208469 0.0017583384 1.617596e-05 1.024706e-04 2 15504145 15504213 69 - 1.486 1.178 -1.077
ENSG00000151779 E050 26.7872046 0.0383863304 1.502908e-03 5.645314e-03 2 15511212 15511350 139 - 1.539 1.169 -1.289
ENSG00000151779 E051 24.4495951 0.0064452764 5.668745e-06 3.985182e-05 2 15534543 15534641 99 - 1.503 1.137 -1.279
ENSG00000151779 E052 20.3132084 0.0022906487 1.695098e-07 1.647841e-06 2 15536418 15536551 134 - 1.441 1.003 -1.553
ENSG00000151779 E053 15.3235390 0.0018320257 8.975880e-05 4.738619e-04 2 15539223 15539356 134 - 1.309 0.962 -1.248
ENSG00000151779 E054 10.8163212 0.0017637633 9.072424e-06 6.088358e-05 2 15551493 15551536 44 - 1.196 0.706 -1.850
ENSG00000151779 E055 12.0205877 0.0014777986 1.547049e-04 7.679184e-04 2 15553426 15553473 48 - 1.215 0.839 -1.387
ENSG00000151779 E056 19.7828796 0.0009428930 2.249074e-06 1.729994e-05 2 15554061 15554138 78 - 1.419 1.040 -1.338
ENSG00000151779 E057 17.1680995 0.0011971768 4.427734e-06 3.189554e-05 2 15556783 15556819 37 - 1.361 0.962 -1.427
ENSG00000151779 E058 22.4842661 0.0008377158 6.797771e-08 7.133932e-07 2 15558580 15558634 55 - 1.476 1.058 -1.473
ENSG00000151779 E059 25.0230372 0.0058790376 9.032547e-07 7.570963e-06 2 15561188 15561334 147 - 1.518 1.122 -1.386