ENSG00000151338

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000396294 ENSG00000151338 HEK293_OSMI2_2hA HEK293_TMG_2hB MIPOL1 protein_coding protein_coding 3.18452 0.5729915 5.922705 0.1295989 0.5729066 3.347143 0.18920730 0.07213618 0.26564471 0.04050152 0.09483045 1.746720 0.05578750 0.16236667 0.043933333 -0.118433333 0.488662367 0.009921285 FALSE TRUE
ENST00000554930 ENSG00000151338 HEK293_OSMI2_2hA HEK293_TMG_2hB MIPOL1 protein_coding processed_transcript 3.18452 0.5729915 5.922705 0.1295989 0.5729066 3.347143 0.62596781 0.11755854 0.97130673 0.11755854 0.55344766 2.943545 0.17734583 0.14126667 0.151033333 0.009766667 0.890494767 0.009921285 FALSE TRUE
ENST00000556615 ENSG00000151338 HEK293_OSMI2_2hA HEK293_TMG_2hB MIPOL1 protein_coding protein_coding 3.18452 0.5729915 5.922705 0.1295989 0.5729066 3.347143 0.31328439 0.00000000 1.07813296 0.00000000 0.56128821 6.765711 0.07761250 0.00000000 0.175200000 0.175200000 0.534060342 0.009921285 FALSE FALSE
ENST00000556753 ENSG00000151338 HEK293_OSMI2_2hA HEK293_TMG_2hB MIPOL1 protein_coding protein_coding 3.18452 0.5729915 5.922705 0.1295989 0.5729066 3.347143 0.25155738 0.00000000 0.70892930 0.00000000 0.09294831 6.167778 0.05589167 0.00000000 0.119000000 0.119000000 0.009921285 0.009921285 FALSE FALSE
ENST00000694961 ENSG00000151338 HEK293_OSMI2_2hA HEK293_TMG_2hB MIPOL1 protein_coding protein_coding 3.18452 0.5729915 5.922705 0.1295989 0.5729066 3.347143 0.72769766 0.02239600 0.93346112 0.02239600 0.49128435 4.864076 0.17944583 0.05016667 0.173533333 0.123366667 0.787841588 0.009921285 FALSE TRUE
ENST00000694964 ENSG00000151338 HEK293_OSMI2_2hA HEK293_TMG_2hB MIPOL1 protein_coding protein_coding 3.18452 0.5729915 5.922705 0.1295989 0.5729066 3.347143 0.22116446 0.10384788 0.39157364 0.01413945 0.03163698 1.818557 0.08965000 0.18980000 0.068200000 -0.121600000 0.073905723 0.009921285 FALSE TRUE
ENST00000694966 ENSG00000151338 HEK293_OSMI2_2hA HEK293_TMG_2hB MIPOL1 protein_coding processed_transcript 3.18452 0.5729915 5.922705 0.1295989 0.5729066 3.347143 0.01300284 0.03749084 0.01794537 0.01308899 0.01794537 -0.765040 0.01587917 0.06226667 0.003433333 -0.058833333 0.010506880 0.009921285   FALSE
ENST00000695503 ENSG00000151338 HEK293_OSMI2_2hA HEK293_TMG_2hB MIPOL1 protein_coding protein_coding 3.18452 0.5729915 5.922705 0.1295989 0.5729066 3.347143 0.06952451 0.04876555 0.13339568 0.03651577 0.07693988 1.286959 0.02753333 0.10140000 0.020700000 -0.080700000 0.557771199 0.009921285 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000151338 E001 0.4449813 0.0229215602 0.28832149 0.42889278 14 37197894 37197912 19 + 0.092 0.278 1.921
ENSG00000151338 E002 0.5922303 0.0180748159 0.43586401 0.57801652 14 37197913 37197929 17 + 0.132 0.278 1.336
ENSG00000151338 E003 0.7394793 0.0158752207 0.57780709 0.70299650 14 37197930 37197931 2 + 0.168 0.278 0.922
ENSG00000151338 E004 0.7394793 0.0158752207 0.57780709 0.70299650 14 37197932 37197932 1 + 0.168 0.278 0.922
ENSG00000151338 E005 0.8867284 0.0157371590 0.71129553 0.80828727 14 37197933 37197936 4 + 0.202 0.278 0.600
ENSG00000151338 E006 1.4758382 0.0087886607 0.88263991 0.92888123 14 37197937 37197949 13 + 0.315 0.278 -0.248
ENSG00000151338 E007 2.2444623 0.0272236271 0.84469992 0.90335579 14 37197950 37197955 6 + 0.404 0.446 0.221
ENSG00000151338 E008 7.3190522 0.0022997295 0.42109932 0.56423461 14 37197956 37198009 54 + 0.801 0.661 -0.569
ENSG00000151338 E009 8.2175356 0.0021422891 0.27777147 0.41737842 14 37198010 37198027 18 + 0.847 0.661 -0.750
ENSG00000151338 E010 8.0723629 0.0023769382 0.29846360 0.43991064 14 37198028 37198036 9 + 0.839 0.661 -0.721
ENSG00000151338 E011 9.1859488 0.0023452559 0.37371845 0.51812975 14 37198037 37198067 31 + 0.882 0.739 -0.563
ENSG00000151338 E012 9.4763960 0.0020886769 0.05553401 0.11889466 14 37198068 37198086 19 + 0.908 0.567 -1.399
ENSG00000151338 E013 9.2602468 0.0042807047 0.18204617 0.30377962 14 37198087 37198092 6 + 0.889 0.662 -0.909
ENSG00000151338 E014 9.1129977 0.0065626523 0.19997643 0.32622024 14 37198093 37198104 12 + 0.882 0.662 -0.883
ENSG00000151338 E015 0.7437457 0.0158861998 0.57797682 0.70314581 14 37198105 37198278 174 + 0.168 0.278 0.921
ENSG00000151338 E016 0.1515154 0.0428336937 0.73162213   14 37207142 37207244 103 + 0.049 0.000 -10.582
ENSG00000151338 E017 1.9511102 0.0073719604 0.64362599 0.75612683 14 37212230 37212356 127 + 0.383 0.278 -0.662
ENSG00000151338 E018 4.2427003 0.0037394683 0.67775328 0.78239185 14 37219553 37219691 139 + 0.584 0.661 0.338
ENSG00000151338 E019 0.0000000       14 37220799 37220918 120 +      
ENSG00000151338 E020 4.1749606 0.0037758864 0.87250984 0.92200546 14 37227726 37227838 113 + 0.597 0.567 -0.137
ENSG00000151338 E021 0.2987644 0.0296339009 1.00000000   14 37234378 37234459 82 + 0.092 0.000 -11.513
ENSG00000151338 E022 1.0287806 0.0118295937 0.43014649 0.57278443 14 37240433 37240461 29 + 0.262 0.000 -12.994
ENSG00000151338 E023 1.3964426 0.0104220796 0.37508328 0.51949732 14 37240462 37240569 108 + 0.262 0.446 1.116
ENSG00000151338 E024 21.0736244 0.0008886166 0.06643205 0.13744719 14 37247103 37247240 138 + 1.217 0.998 -0.789
ENSG00000151338 E025 0.0000000       14 37247799 37247828 30 +      
ENSG00000151338 E026 17.0587700 0.0095359943 0.34403330 0.48808600 14 37247829 37247907 79 + 1.123 0.998 -0.456
ENSG00000151338 E027 0.4439371 0.0216523908 1.00000000 1.00000000 14 37265207 37265281 75 + 0.132 0.000 -12.028
ENSG00000151338 E028 8.8930215 0.0018798802 0.42309568 0.56621625 14 37266938 37266950 13 + 0.868 0.739 -0.510
ENSG00000151338 E029 17.9212139 0.0009870232 0.06766833 0.13947952 14 37266951 37267066 116 + 1.150 0.912 -0.871
ENSG00000151338 E030 21.7156961 0.0009238377 0.31295550 0.45546612 14 37267067 37267169 103 + 1.214 1.102 -0.399
ENSG00000151338 E031 24.5913024 0.0007889463 0.06393658 0.13324891 14 37268658 37268793 136 + 1.275 1.070 -0.730
ENSG00000151338 E032 21.1256653 0.0008746055 0.81266384 0.88119789 14 37270420 37270525 106 + 1.185 1.211 0.092
ENSG00000151338 E033 6.9775271 0.0025516395 0.22174416 0.35247871 14 37276330 37278874 2545 + 0.792 0.567 -0.952
ENSG00000151338 E034 15.8388284 0.0056932494 0.37920695 0.52348480 14 37285318 37285372 55 + 1.057 1.160 0.374
ENSG00000151338 E035 19.5840960 0.0162797854 0.76028381 0.84444430 14 37285373 37285447 75 + 1.153 1.188 0.127
ENSG00000151338 E036 6.0301007 0.0065203582 0.49410258 0.63109309 14 37288580 37290205 1626 + 0.690 0.805 0.464
ENSG00000151338 E037 2.1036552 0.0069503595 0.25213193 0.38845897 14 37290206 37290368 163 + 0.339 0.567 1.188
ENSG00000151338 E038 0.0000000       14 37302501 37306476 3976 +      
ENSG00000151338 E039 15.9691255 0.0176285794 0.41327294 0.55678372 14 37308056 37308089 34 + 1.061 1.162 0.364
ENSG00000151338 E040 23.8116176 0.0011618396 0.08831047 0.17254340 14 37308349 37308457 109 + 1.211 1.370 0.557
ENSG00000151338 E041 18.4265826 0.0010180084 0.59808151 0.71974710 14 37308458 37308519 62 + 1.127 1.186 0.209
ENSG00000151338 E042 0.0000000       14 37350091 37350214 124 +      
ENSG00000151338 E043 20.5114892 0.0008981573 0.55183766 0.68125917 14 37369517 37369624 108 + 1.171 1.234 0.222
ENSG00000151338 E044 0.1451727 0.0426687447 0.72937364   14 37369625 37369939 315 + 0.048 0.000 -10.582
ENSG00000151338 E045 0.0000000       14 37385494 37385779 286 +      
ENSG00000151338 E046 0.8062886 0.0175639416 0.57595880 0.70147457 14 37396976 37397014 39 + 0.168 0.278 0.925
ENSG00000151338 E047 0.0000000       14 37399745 37399748 4 +      
ENSG00000151338 E048 0.0000000       14 37399749 37399749 1 +      
ENSG00000151338 E049 0.0000000       14 37399750 37399754 5 +      
ENSG00000151338 E050 0.0000000       14 37399755 37399799 45 +      
ENSG00000151338 E051 0.0000000       14 37399800 37400059 260 +      
ENSG00000151338 E052 0.0000000       14 37400060 37402113 2054 +      
ENSG00000151338 E053 0.0000000       14 37402114 37402226 113 +      
ENSG00000151338 E054 0.0000000       14 37402227 37402528 302 +      
ENSG00000151338 E055 0.7415557 0.1394779694 0.59046269 0.71332435 14 37406567 37406670 104 + 0.168 0.276 0.911
ENSG00000151338 E056 0.0000000       14 37417326 37417486 161 +      
ENSG00000151338 E057 0.0000000       14 37419228 37419459 232 +      
ENSG00000151338 E058 17.9668879 0.0011276844 0.15066604 0.26257561 14 37422855 37422949 95 + 1.104 1.256 0.541
ENSG00000151338 E059 1.6167550 0.0086358534 0.02323785 0.05824050 14 37423525 37424588 1064 + 0.233 0.661 2.339
ENSG00000151338 E060 0.0000000       14 37430597 37431559 963 +      
ENSG00000151338 E061 0.3666179 0.0274594948 0.14406508 0.25353873 14 37437608 37437724 117 + 0.048 0.278 2.926
ENSG00000151338 E062 2.1733841 0.0741072876 0.03316309 0.07813169 14 37476892 37477062 171 + 0.314 0.737 2.067
ENSG00000151338 E063 29.3277431 0.0007220611 0.57699034 0.70233807 14 37499908 37500138 231 + 1.319 1.369 0.175
ENSG00000151338 E064 0.8168978 0.0153787590 0.57702637 0.70236840 14 37501517 37507790 6274 + 0.168 0.278 0.924
ENSG00000151338 E065 0.0000000       14 37510588 37510668 81 +      
ENSG00000151338 E066 0.0000000       14 37515884 37516689 806 +      
ENSG00000151338 E067 0.0000000       14 37518372 37519235 864 +      
ENSG00000151338 E068 13.4399185 0.0013262084 0.06697756 0.13835013 14 37520958 37523472 2515 + 0.973 1.186 0.773
ENSG00000151338 E069 0.0000000       14 37523473 37523569 97 +      
ENSG00000151338 E070 0.2944980 0.3574967305 1.00000000   14 37523570 37524557 988 + 0.092 0.000 -11.036
ENSG00000151338 E071 0.2214452 0.0367652799 0.04300429   14 37535926 37536047 122 + 0.000 0.278 13.627
ENSG00000151338 E072 0.1515154 0.0428336937 0.73162213   14 37536048 37538619 2572 + 0.049 0.000 -10.582
ENSG00000151338 E073 0.2214452 0.0367652799 0.04300429   14 37538620 37539077 458 + 0.000 0.278 13.627
ENSG00000151338 E074 0.1451727 0.0426687447 0.72937364   14 37545665 37546904 1240 + 0.048 0.000 -10.582
ENSG00000151338 E075 86.7418271 0.0014282205 0.89183198 0.93492208 14 37546905 37553986 7082 + 1.783 1.792 0.029
ENSG00000151338 E076 0.1515154 0.0428336937 0.73162213   14 37564047 37564218 172 + 0.049 0.000 -10.582
ENSG00000151338 E077 0.2987644 0.0296339009 1.00000000   14 37564219 37564362 144 + 0.092 0.000 -11.513
ENSG00000151338 E078 0.2987644 0.0296339009 1.00000000   14 37564363 37564366 4 + 0.092 0.000 -11.513
ENSG00000151338 E079 1.6712722 0.0185222726 0.16742655 0.28485369 14 37564367 37569053 4687 + 0.289 0.566 1.505
ENSG00000151338 E080 0.4804688 0.0225450126 0.28756793 0.42806426 14 37578704 37579125 422 + 0.092 0.278 1.923