ENSG00000151332

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000318473 ENSG00000151332 HEK293_OSMI2_2hA HEK293_TMG_2hB MBIP protein_coding protein_coding 19.08615 6.110275 32.22797 0.3638671 1.567685 2.397093 1.550589 1.33571371 2.007297 0.30733694 0.05859047 0.584052 0.09447917 0.2200333 0.06253333 -0.1575 6.291680e-04 3.061932e-17 FALSE TRUE
ENST00000416007 ENSG00000151332 HEK293_OSMI2_2hA HEK293_TMG_2hB MBIP protein_coding protein_coding 19.08615 6.110275 32.22797 0.3638671 1.567685 2.397093 9.981352 4.06929425 16.754176 0.42539098 1.54311118 2.038990 0.61093750 0.6664333 0.51813333 -0.1483 1.731759e-01 3.061932e-17 FALSE TRUE
ENST00000604336 ENSG00000151332 HEK293_OSMI2_2hA HEK293_TMG_2hB MBIP protein_coding protein_coding 19.08615 6.110275 32.22797 0.3638671 1.567685 2.397093 1.251621 0.05342029 1.948136 0.05342029 0.58248908 4.948393 0.05500000 0.0080000 0.05940000 0.0514 6.768828e-02 3.061932e-17 FALSE TRUE
ENST00000605579 ENSG00000151332 HEK293_OSMI2_2hA HEK293_TMG_2hB MBIP protein_coding protein_coding 19.08615 6.110275 32.22797 0.3638671 1.567685 2.397093 3.596119 0.00000000 6.488787 0.00000000 0.50272275 9.344027 0.11235417 0.0000000 0.20340000 0.2034 3.061932e-17 3.061932e-17 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000151332 E001 1.0705211 0.0119256067 3.748240e-02 8.637022e-02 14 36298564 36298567 4 - 0.176 0.549 2.349
ENSG00000151332 E002 6.2750911 0.0028613022 1.270744e-09 1.847006e-08 14 36298568 36298589 22 - 0.477 1.228 2.995
ENSG00000151332 E003 165.8817962 0.0003411294 5.762681e-08 6.126733e-07 14 36298590 36299116 527 - 2.113 2.271 0.531
ENSG00000151332 E004 60.3052578 0.0003809174 4.687309e-01 6.081169e-01 14 36299117 36299117 1 - 1.711 1.746 0.120
ENSG00000151332 E005 94.6656481 0.0003394903 1.344901e-01 2.403972e-01 14 36299118 36299187 70 - 1.899 1.958 0.199
ENSG00000151332 E006 48.1230762 0.0075381143 8.736065e-01 9.227652e-01 14 36299188 36299190 3 - 1.625 1.637 0.044
ENSG00000151332 E007 69.5574877 0.0004753102 3.593157e-01 5.036608e-01 14 36300785 36300823 39 - 1.772 1.815 0.143
ENSG00000151332 E008 1.0684327 0.0144761877 6.241055e-01 7.405501e-01 14 36300824 36301020 197 - 0.263 0.356 0.614
ENSG00000151332 E009 2.6678867 0.0056834714 7.609567e-01 8.449192e-01 14 36305089 36305304 216 - 0.522 0.464 -0.285
ENSG00000151332 E010 0.3332198 0.0322144071 3.240374e-01   14 36308017 36308091 75 - 0.067 0.214 1.936
ENSG00000151332 E011 72.4562959 0.0011168190 3.129779e-01 4.554918e-01 14 36308092 36308156 65 - 1.788 1.835 0.159
ENSG00000151332 E012 71.8777461 0.0020571015 6.701378e-01 7.766721e-01 14 36308157 36308189 33 - 1.791 1.810 0.067
ENSG00000151332 E013 67.2670606 0.0004272057 4.614877e-01 6.014382e-01 14 36311573 36311576 4 - 1.776 1.736 -0.135
ENSG00000151332 E014 134.4267489 0.0002520075 5.878159e-01 7.110745e-01 14 36311577 36311725 149 - 2.070 2.048 -0.072
ENSG00000151332 E015 85.9198077 0.0012098782 6.590319e-01 7.679632e-01 14 36311959 36312024 66 - 1.868 1.885 0.056
ENSG00000151332 E016 17.2241074 0.0032284365 1.096252e-07 1.105513e-06 14 36313290 36314511 1222 - 1.293 0.550 -2.871
ENSG00000151332 E017 109.9579898 0.0003368494 3.875450e-01 5.316844e-01 14 36314512 36314608 97 - 1.971 2.001 0.103
ENSG00000151332 E018 75.2638024 0.0007082816 7.244589e-01 8.179614e-01 14 36314691 36314700 10 - 1.813 1.827 0.048
ENSG00000151332 E019 164.2513575 0.0002855769 2.255771e-04 1.072852e-03 14 36314701 36314915 215 - 2.177 2.051 -0.423
ENSG00000151332 E020 1.9113563 0.0092041685 2.045132e-01 3.318096e-01 14 36314916 36314936 21 - 0.476 0.214 -1.649
ENSG00000151332 E021 116.4609466 0.0035557716 8.039454e-04 3.273055e-03 14 36316693 36316812 120 - 2.035 1.865 -0.572
ENSG00000151332 E022 4.6566640 0.0034030949 4.559557e-03 1.470889e-02 14 36319585 36319870 286 - 0.777 0.214 -2.970
ENSG00000151332 E023 84.2987853 0.0011979987 9.623880e-03 2.783917e-02 14 36320460 36320637 178 - 1.891 1.761 -0.439