ENSG00000151208

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-3 / 3
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000372391	ENSG00000151208	HEK293_OSMI2_2hA	HEK293_TMG_2hB	DLG5	protein_coding	protein_coding	17.89269	22.38033	14.95297	0.6829095	0.08773562	-0.5814794	8.939185	8.4205683	9.760622	0.94869331	0.04676578	0.2128205	0.52099167	0.37440000	0.65286667	0.2784667	6.201748e-08	1.105731e-11	FALSE	TRUE
ENST00000424842	ENSG00000151208	HEK293_OSMI2_2hA	HEK293_TMG_2hB	DLG5	protein_coding	protein_coding	17.89269	22.38033	14.95297	0.6829095	0.08773562	-0.5814794	7.062905	12.9510353	3.146906	0.36400527	0.25967255	-2.0375975	0.36270833	0.58066667	0.21026667	-0.3704000	1.105731e-11	1.105731e-11	FALSE	TRUE
MSTRG.4240.4	ENSG00000151208	HEK293_OSMI2_2hA	HEK293_TMG_2hB	DLG5	protein_coding		17.89269	22.38033	14.95297	0.6829095	0.08773562	-0.5814794	0.677658	0.2604649	1.026916	0.07153257	0.21006051	1.9387850	0.04347917	0.01153333	0.06883333	0.0573000	9.708218e-05	1.105731e-11	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
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width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000151208	E001	734.7159086	0.0058374744	1.215814e-17	5.896884e-16	10	77790791	77791708	918	-	2.620	2.962	1.139
ENSG00000151208	E002	254.8492258	0.0008210690	2.839986e-05	1.698585e-04	10	77791709	77791900	192	-	2.311	2.446	0.451
ENSG00000151208	E003	284.8593628	0.0002114951	1.066771e-07	1.078078e-06	10	77791901	77792195	295	-	2.350	2.494	0.477
ENSG00000151208	E004	250.1889334	0.0001783298	6.077848e-09	7.811602e-08	10	77792196	77792543	348	-	2.283	2.445	0.541
ENSG00000151208	E005	2.6174204	0.0062840936	1.170898e-01	2.157918e-01	10	77793544	77794007	464	-	0.669	0.437	-1.082
ENSG00000151208	E006	168.1543700	0.0003313368	4.822340e-01	6.203969e-01	10	77794008	77794117	110	-	2.191	2.235	0.149
ENSG00000151208	E007	172.4187679	0.0046761160	8.964664e-01	9.378109e-01	10	77794849	77794958	110	-	2.217	2.238	0.069
ENSG00000151208	E008	178.7555341	0.0055499771	4.589445e-01	5.991790e-01	10	77796061	77796188	128	-	2.209	2.266	0.193
ENSG00000151208	E009	164.4720365	0.0003400519	3.396246e-02	7.968008e-02	10	77796451	77796594	144	-	2.154	2.240	0.288
ENSG00000151208	E010	184.1183372	0.0001878344	2.164975e-01	3.461894e-01	10	77805665	77805861	197	-	2.219	2.277	0.193
ENSG00000151208	E011	1.9112782	0.0101959709	6.131156e-01	7.319117e-01	10	77805862	77805928	67	-	0.505	0.436	-0.347
ENSG00000151208	E012	1.6929403	0.0116277483	8.492240e-01	9.064204e-01	10	77806105	77806171	67	-	0.452	0.436	-0.086
ENSG00000151208	E013	95.2922952	0.0003228896	8.118487e-01	8.806215e-01	10	77806758	77806795	38	-	1.960	1.976	0.052
ENSG00000151208	E014	154.4266408	0.0002696508	6.397555e-01	7.530882e-01	10	77806796	77806928	133	-	2.173	2.184	0.036
ENSG00000151208	E015	164.3475814	0.0026783609	9.190017e-01	9.528349e-01	10	77807796	77807936	141	-	2.195	2.216	0.071
ENSG00000151208	E016	91.1088999	0.0004150838	9.279577e-01	9.586428e-01	10	77807937	77807944	8	-	1.942	1.963	0.070
ENSG00000151208	E017	0.6600969	0.0565878960	7.720011e-01	8.528585e-01	10	77807945	77807977	33	-	0.239	0.198	-0.344
ENSG00000151208	E018	177.1940248	0.0002364024	5.783468e-01	7.034666e-01	10	77809547	77809730	184	-	2.233	2.242	0.031
ENSG00000151208	E019	124.9448767	0.0010687343	5.940521e-01	7.163359e-01	10	77811094	77811234	141	-	2.060	2.103	0.146
ENSG00000151208	E020	111.4764557	0.0032807855	8.378833e-01	8.986428e-01	10	77811924	77812057	134	-	2.029	2.045	0.051
ENSG00000151208	E021	124.5133547	0.0002387892	6.631828e-01	7.713103e-01	10	77812215	77812377	163	-	2.064	2.102	0.129
ENSG00000151208	E022	1.8475737	0.0161831316	1.602492e-02	4.279071e-02	10	77816033	77816175	143	-	0.136	0.589	2.972
ENSG00000151208	E023	132.9686750	0.0003137585	2.838027e-01	4.239869e-01	10	77816551	77816701	151	-	2.077	2.136	0.196
ENSG00000151208	E024	100.4249074	0.0004078790	2.763512e-01	4.158042e-01	10	77817007	77817096	90	-	1.953	2.017	0.216
ENSG00000151208	E025	94.3980326	0.0016728183	8.902000e-01	9.338528e-01	10	77817777	77817889	113	-	1.948	1.978	0.101
ENSG00000151208	E026	105.8772605	0.0051716290	7.711307e-01	8.522498e-01	10	77819321	77819465	145	-	2.009	2.020	0.035
ENSG00000151208	E027	1.5606435	0.0089020947	1.705656e-02	4.506147e-02	10	77819466	77819476	11	-	0.595	0.198	-2.346
ENSG00000151208	E028	7.3692157	0.0359876656	6.692199e-02	1.382540e-01	10	77819477	77819894	418	-	1.038	0.795	-0.924
ENSG00000151208	E029	93.2842353	0.0159488711	6.556628e-01	7.655017e-01	10	77819895	77820018	124	-	1.965	1.959	-0.019
ENSG00000151208	E030	16.6333202	0.0010850409	2.451307e-02	6.087761e-02	10	77820019	77821081	1063	-	1.326	1.163	-0.573
ENSG00000151208	E031	243.7205414	0.0020046884	2.378913e-02	5.938020e-02	10	77821082	77821781	700	-	2.403	2.359	-0.146
ENSG00000151208	E032	153.3597710	0.0016180630	3.466045e-02	8.099966e-02	10	77821782	77822101	320	-	2.204	2.157	-0.157
ENSG00000151208	E033	78.7825816	0.0004903676	5.677365e-02	1.210712e-01	10	77824384	77824476	93	-	1.918	1.865	-0.180
ENSG00000151208	E034	1.1802934	0.0113849563	4.484884e-01	5.897711e-01	10	77824477	77824730	254	-	0.392	0.271	-0.760
ENSG00000151208	E035	90.9586454	0.0003841866	9.887980e-03	2.848787e-02	10	77828882	77828985	104	-	1.992	1.919	-0.245
ENSG00000151208	E036	132.0888878	0.0003362067	6.450865e-06	4.478350e-05	10	77829355	77829530	176	-	2.179	2.062	-0.392
ENSG00000151208	E037	134.5687363	0.0002565186	1.315483e-08	1.586240e-07	10	77830217	77830344	128	-	2.204	2.053	-0.504
ENSG00000151208	E038	121.4445901	0.0051789485	2.490531e-05	1.511141e-04	10	77830741	77830873	133	-	2.171	1.998	-0.580
ENSG00000151208	E039	98.8719710	0.0064839569	1.655194e-03	6.138229e-03	10	77833914	77834039	126	-	2.066	1.927	-0.466
ENSG00000151208	E040	129.1506309	0.0027706866	1.965067e-08	2.294884e-07	10	77835738	77835922	185	-	2.211	2.013	-0.662
ENSG00000151208	E041	164.1557490	0.0042766454	8.030904e-07	6.805470e-06	10	77841881	77842193	313	-	2.305	2.128	-0.594
ENSG00000151208	E042	131.2585983	0.0002522709	5.207300e-11	9.641121e-10	10	77843447	77843706	260	-	2.209	2.029	-0.601
ENSG00000151208	E043	0.3299976	0.0274424043	2.922581e-01		10	77845211	77845437	227	-	0.000	0.198	9.344
ENSG00000151208	E044	104.1934115	0.0002605025	2.949966e-13	7.844780e-12	10	77853354	77853537	184	-	2.135	1.907	-0.765
ENSG00000151208	E045	82.2330979	0.0003232992	1.358549e-11	2.769238e-10	10	77854227	77854358	132	-	2.040	1.802	-0.801
ENSG00000151208	E046	28.3143320	0.0102354254	4.581086e-03	1.476703e-02	10	77854359	77854370	12	-	1.572	1.369	-0.697
ENSG00000151208	E047	70.6796302	0.0003558892	2.036679e-07	1.948701e-06	10	77856730	77856892	163	-	1.951	1.758	-0.651
ENSG00000151208	E048	0.0000000				10	77869099	77869128	30	-
ENSG00000151208	E049	36.2482088	0.0009944003	9.860581e-04	3.911179e-03	10	77869129	77869197	69	-	1.650	1.480	-0.581
ENSG00000151208	E050	0.0000000				10	77889429	77889507	79	-
ENSG00000151208	E051	50.9955531	0.0184362132	8.457993e-04	3.422636e-03	10	77926217	77926935	719	-	1.831	1.591	-0.814

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000151208

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3