ENSG00000147202

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000324765 ENSG00000147202 HEK293_OSMI2_2hA HEK293_TMG_2hB DIAPH2 protein_coding protein_coding 3.60954 1.55729 6.553353 0.07012749 0.1763322 2.066161 0.2763086 0.00000000 0.000000 0.00000000 0.00000000 0.000000 0.1179083 0.0000 0.0000000 0.00000000   0.000385654 FALSE TRUE
ENST00000373049 ENSG00000147202 HEK293_OSMI2_2hA HEK293_TMG_2hB DIAPH2 protein_coding protein_coding 3.60954 1.55729 6.553353 0.07012749 0.1763322 2.066161 0.4448550 0.03506742 1.049559 0.03506742 0.10597407 4.555236 0.1106500 0.0207 0.1596333 0.13893333 0.000385654 0.000385654 FALSE TRUE
MSTRG.34576.3 ENSG00000147202 HEK293_OSMI2_2hA HEK293_TMG_2hB DIAPH2 protein_coding   3.60954 1.55729 6.553353 0.07012749 0.1763322 2.066161 2.0605781 0.85326887 3.784024 0.02733573 0.06463194 2.135847 0.5086958 0.5490 0.5783667 0.02936667 0.858857306 0.000385654 FALSE TRUE
MSTRG.34576.4 ENSG00000147202 HEK293_OSMI2_2hA HEK293_TMG_2hB DIAPH2 protein_coding   3.60954 1.55729 6.553353 0.07012749 0.1763322 2.066161 0.8277983 0.66895348 1.719770 0.02098499 0.09595061 1.349195 0.2627583 0.4303 0.2620000 -0.16830000 0.013060969 0.000385654 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000147202 E001 2.254141 0.0063937112 9.276074e-02 1.794342e-01 X 96684712 96684841 130 + 0.545 0.202 -2.088
ENSG00000147202 E002 1.920921 0.0072274176 1.835995e-02 4.792150e-02 X 96684842 96684850 9 + 0.523 0.001 -10.629
ENSG00000147202 E003 4.340194 0.0057923834 2.197494e-02 5.562203e-02 X 96684851 96684867 17 + 0.767 0.339 -2.037
ENSG00000147202 E004 26.269818 0.0156607401 8.842779e-04 3.558960e-03 X 96684868 96685190 323 + 1.459 1.087 -1.306
ENSG00000147202 E005 10.118934 0.0145281832 1.591557e-02 4.254338e-02 X 96735758 96735790 33 + 1.070 0.711 -1.378
ENSG00000147202 E006 26.969900 0.0130157090 9.346372e-04 3.735235e-03 X 96738586 96738762 177 + 1.467 1.108 -1.260
ENSG00000147202 E007 24.823317 0.0492169260 2.968656e-03 1.016967e-02 X 96758154 96758258 105 + 1.444 0.996 -1.589
ENSG00000147202 E008 11.649025 0.1781858621 1.796378e-02 4.705749e-02 X 96763100 96763120 21 + 1.147 0.600 -2.131
ENSG00000147202 E009 28.440273 0.0321914956 4.899318e-03 1.564946e-02 X 96881579 96881718 140 + 1.489 1.129 -1.260
ENSG00000147202 E010 20.587098 0.0137583932 6.409918e-05 3.515263e-04 X 96912328 96912402 75 + 1.372 0.875 -1.795
ENSG00000147202 E011 17.354928 0.0010778904 8.880998e-03 2.598302e-02 X 96912483 96912552 70 + 1.273 0.994 -1.003
ENSG00000147202 E012 23.072285 0.0029845014 2.341250e-02 5.860534e-02 X 96916438 96916574 137 + 1.380 1.164 -0.758
ENSG00000147202 E013 22.178112 0.0008638469 1.044536e-01 1.972726e-01 X 96918509 96918617 109 + 1.349 1.198 -0.532
ENSG00000147202 E014 22.662861 0.0008497192 1.232753e-01 2.246432e-01 X 96930733 96930843 111 + 1.356 1.214 -0.499
ENSG00000147202 E015 21.249704 0.0014182221 3.752484e-01 5.196611e-01 X 96937233 96937351 119 + 1.317 1.229 -0.307
ENSG00000147202 E016 25.028452 0.0024951389 3.339206e-02 7.855978e-02 X 96939266 96939382 117 + 1.408 1.214 -0.678
ENSG00000147202 E017 25.221722 0.0537623614 2.214626e-01 3.521591e-01 X 96942018 96942136 119 + 1.406 1.246 -0.557
ENSG00000147202 E018 16.989188 0.0014241661 2.126042e-01 3.416219e-01 X 96945527 96945591 65 + 1.239 1.107 -0.467
ENSG00000147202 E019 18.415111 0.0032973780 9.184085e-01 9.524455e-01 X 96948935 96949039 105 + 1.247 1.229 -0.066
ENSG00000147202 E020 42.483976 0.0005597734 9.089644e-01 9.461726e-01 X 96957828 96958148 321 + 1.591 1.589 -0.009
ENSG00000147202 E021 33.130094 0.0006155528 7.132862e-01 8.098237e-01 X 96965093 96965207 115 + 1.478 1.493 0.052
ENSG00000147202 E022 35.056840 0.0046622104 3.261326e-01 4.695789e-01 X 97072941 97073042 102 + 1.488 1.547 0.202
ENSG00000147202 E023 34.592707 0.0006421906 8.483396e-01 9.058165e-01 X 97075167 97075261 95 + 1.498 1.501 0.010
ENSG00000147202 E024 33.275466 0.0075549039 9.217778e-01 9.546376e-01 X 97099694 97099795 102 + 1.481 1.478 -0.010
ENSG00000147202 E025 50.518346 0.0055627871 9.397741e-01 9.661716e-01 X 97114726 97114965 240 + 1.661 1.656 -0.017
ENSG00000147202 E026 38.279954 0.0092033439 5.633630e-01 6.908505e-01 X 97141665 97141794 130 + 1.534 1.568 0.117
ENSG00000147202 E027 33.327006 0.0079718712 2.372291e-01 3.709738e-01 X 97247715 97247839 125 + 1.459 1.541 0.278
ENSG00000147202 E028 49.144957 0.0036784137 1.575083e-03 5.878659e-03 X 97348116 97348280 165 + 1.593 1.770 0.599
ENSG00000147202 E029 43.885210 0.0053623948 4.034700e-03 1.323960e-02 X 97383909 97384044 136 + 1.547 1.723 0.598
ENSG00000147202 E030 30.715477 0.0115838036 6.891588e-02 1.415750e-01 X 97429650 97429745 96 + 1.411 1.552 0.483
ENSG00000147202 E031 14.894030 0.0787021461 1.328696e-01 2.381005e-01 X 97469694 97469835 142 + 1.078 1.322 0.864
ENSG00000147202 E032 177.808815 0.0003258688 2.506744e-14 7.771151e-13 X 97599253 97604997 5745 + 2.141 2.332 0.639