ENSG00000147082

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000276014 ENSG00000147082 HEK293_OSMI2_2hA HEK293_TMG_2hB CCNB3 protein_coding protein_coding 0.3708644 0.3322719 0.7855359 0.09154648 0.06410102 1.216784 0.16942999 0.09409711 0.1609552 0.09409711 0.160955187 0.7156882 0.51899167 0.3333333 0.1787333 -0.15460000 0.9547415466 0.0004770492 FALSE TRUE
ENST00000348603 ENSG00000147082 HEK293_OSMI2_2hA HEK293_TMG_2hB CCNB3 protein_coding protein_coding 0.3708644 0.3322719 0.7855359 0.09154648 0.06410102 1.216784 0.01293592 0.06365192 0.0000000 0.06365192 0.000000000 -2.8807232 0.02525000 0.1248667 0.0000000 -0.12486667 0.4397123632 0.0004770492 FALSE TRUE
ENST00000376038 ENSG00000147082 HEK293_OSMI2_2hA HEK293_TMG_2hB CCNB3 protein_coding protein_coding 0.3708644 0.3322719 0.7855359 0.09154648 0.06410102 1.216784 0.01293592 0.06365192 0.0000000 0.06365192 0.000000000 -2.8807232 0.02525000 0.1248667 0.0000000 -0.12486667 0.4397123632 0.0004770492 FALSE TRUE
ENST00000376042 ENSG00000147082 HEK293_OSMI2_2hA HEK293_TMG_2hB CCNB3 protein_coding protein_coding 0.3708644 0.3322719 0.7855359 0.09154648 0.06410102 1.216784 0.11724403 0.11087093 0.3457576 0.05970754 0.105237498 1.5574274 0.31191250 0.4169667 0.4610333 0.04406667 0.9113939897 0.0004770492 FALSE TRUE
ENST00000491907 ENSG00000147082 HEK293_OSMI2_2hA HEK293_TMG_2hB CCNB3 protein_coding processed_transcript 0.3708644 0.3322719 0.7855359 0.09154648 0.06410102 1.216784 0.04842023 0.00000000 0.2788230 0.00000000 0.002671505 4.8521140 0.07506667 0.0000000 0.3602667 0.36026667 0.0004770492 0.0004770492   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000147082 E001 0.0000000       X 50202713 50202810 98 +      
ENSG00000147082 E002 0.2924217 0.028695273 0.3747729030   X 50204495 50204562 68 + 0.181 0.000 -9.611
ENSG00000147082 E003 0.4439371 0.022023236 0.1930087854 0.317552031 X 50204563 50204610 48 + 0.249 0.000 -12.222
ENSG00000147082 E004 1.1802934 0.012155413 0.7784943421 0.857481672 X 50204765 50204944 180 + 0.308 0.349 0.258
ENSG00000147082 E005 0.4428904 0.556252116 0.1945199322 0.319404938 X 50204945 50204950 6 + 0.000 0.273 11.393
ENSG00000147082 E006 0.0000000       X 50284536 50284541 6 +      
ENSG00000147082 E007 1.2682218 0.012902237 0.4503235865 0.591424914 X 50284542 50284616 75 + 0.406 0.260 -0.913
ENSG00000147082 E008 2.4872396 0.007285189 0.1006802548 0.191499806 X 50285127 50285245 119 + 0.639 0.349 -1.444
ENSG00000147082 E009 1.1543840 0.016605493 0.6227116514 0.739446611 X 50285246 50285259 14 + 0.360 0.261 -0.649
ENSG00000147082 E010 3.3289260 0.005113287 0.9678802045 0.983912863 X 50288780 50288887 108 + 0.639 0.632 -0.029
ENSG00000147082 E011 3.3173744 0.005110518 0.1728573673 0.291914938 X 50294863 50294993 131 + 0.710 0.485 -1.005
ENSG00000147082 E012 27.0124922 0.013696863 0.0173834556 0.045784005 X 50308505 50311496 2992 + 1.508 1.334 -0.600
ENSG00000147082 E013 3.6440386 0.060278037 0.1122059345 0.208762941 X 50312537 50312632 96 + 0.770 0.484 -1.259
ENSG00000147082 E014 2.6831009 0.068997481 0.0788286632 0.157644844 X 50313856 50313948 93 + 0.687 0.347 -1.658
ENSG00000147082 E015 0.0000000       X 50341707 50342201 495 +      
ENSG00000147082 E016 4.4306656 0.003785416 0.0563978637 0.120418890 X 50342202 50342339 138 + 0.612 0.855 0.993
ENSG00000147082 E017 5.2724643 0.003462185 0.0005429406 0.002320657 X 50346652 50346807 156 + 0.554 0.984 1.742
ENSG00000147082 E018 5.4467818 0.003415917 0.0010834520 0.004247687 X 50347626 50347775 150 + 0.584 0.984 1.605
ENSG00000147082 E019 5.2639224 0.032846327 0.1559549328 0.269737834 X 50351241 50351371 131 + 0.709 0.899 0.750
ENSG00000147082 E020 3.5019972 0.104985373 0.7827536068 0.860527042 X 50351607 50351716 110 + 0.638 0.698 0.253
ENSG00000147082 E021 1.9896154 0.012231657 0.5460329912 0.676279000 X 50351717 50351910 194 + 0.448 0.539 0.446
ENSG00000147082 E022 0.0000000       X 50351911 50351914 4 +