ENSG00000145555

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000510401	ENSG00000145555	HEK293_OSMI2_2hA	HEK293_TMG_2hB	MYO10	protein_coding	processed_transcript	5.581996	5.0369	5.965966	0.449268	0.2337983	0.2437746	0.6755467	0.000000	1.0682610	0.0000000	0.38074570	6.7525627	0.1084542	0.0000000	0.1751333	0.1751333	1.003963e-06	2.555761e-35	FALSE	FALSE
ENST00000513610	ENSG00000145555	HEK293_OSMI2_2hA	HEK293_TMG_2hB	MYO10	protein_coding	protein_coding	5.581996	5.0369	5.965966	0.449268	0.2337983	0.2437746	2.1294107	2.769600	1.4621149	0.1697133	0.16713457	-0.9169871	0.3975333	0.5530667	0.2446667	-0.3084000	2.016116e-07	2.555761e-35	FALSE	TRUE
ENST00000515803	ENSG00000145555	HEK293_OSMI2_2hA	HEK293_TMG_2hB	MYO10	protein_coding	protein_coding	5.581996	5.0369	5.965966	0.449268	0.2337983	0.2437746	1.2833920	2.194318	0.2954139	0.2810695	0.21067269	-2.8514949	0.2409542	0.4324667	0.0514000	-0.3810667	1.642722e-02	2.555761e-35	FALSE	TRUE
MSTRG.25975.4	ENSG00000145555	HEK293_OSMI2_2hA	HEK293_TMG_2hB	MYO10	protein_coding		5.581996	5.0369	5.965966	0.449268	0.2337983	0.2437746	1.3954677	0.000000	2.8629343	0.0000000	0.02417371	8.1663812	0.2356125	0.0000000	0.4814000	0.4814000	2.555761e-35	2.555761e-35	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000145555	E001	0.000000				5	16661907	16661913	7	-
ENSG00000145555	E002	285.292274	0.0073232468	6.943479e-14	2.017819e-12	5	16661914	16666379	4466	-	2.217	2.580	1.209
ENSG00000145555	E003	65.935352	0.0143167309	2.728358e-05	1.639273e-04	5	16666380	16666444	65	-	1.599	1.946	1.174
ENSG00000145555	E004	70.711748	0.0062825772	2.007339e-05	1.244508e-04	5	16666445	16666561	117	-	1.675	1.956	0.947
ENSG00000145555	E005	86.598066	0.0070373464	4.457041e-06	3.209812e-05	5	16666562	16666793	232	-	1.753	2.047	0.990
ENSG00000145555	E006	72.604813	0.0007966383	3.353892e-06	2.484981e-05	5	16668277	16668468	192	-	1.716	1.955	0.807
ENSG00000145555	E007	125.045157	0.0003809635	3.533882e-04	1.593325e-03	5	16670526	16670978	453	-	2.006	2.157	0.508
ENSG00000145555	E008	49.440422	0.0066949970	5.957554e-01	7.178004e-01	5	16671422	16671542	121	-	1.657	1.727	0.238
ENSG00000145555	E009	55.215758	0.0055711714	2.909561e-02	7.018802e-02	5	16672689	16672825	137	-	1.644	1.810	0.563
ENSG00000145555	E010	63.544925	0.0004682371	3.775871e-02	8.688433e-02	5	16673682	16673889	208	-	1.724	1.854	0.438
ENSG00000145555	E011	81.620935	0.0003609067	6.757667e-01	7.809314e-01	5	16674853	16675150	298	-	1.900	1.920	0.068
ENSG00000145555	E012	45.375204	0.0005791579	2.065648e-01	3.344194e-01	5	16676031	16676154	124	-	1.672	1.642	-0.101
ENSG00000145555	E013	43.314281	0.0005658834	7.909599e-01	8.663099e-01	5	16679947	16680104	158	-	1.624	1.646	0.074
ENSG00000145555	E014	42.156436	0.0074034763	5.188160e-01	6.529791e-01	5	16681309	16681503	195	-	1.581	1.663	0.281
ENSG00000145555	E015	43.790349	0.0139559582	8.201119e-01	8.864885e-01	5	16681871	16682013	143	-	1.631	1.656	0.086
ENSG00000145555	E016	31.045502	0.0063663327	6.316742e-01	7.466420e-01	5	16683880	16683935	56	-	1.460	1.532	0.247
ENSG00000145555	E017	34.379732	0.0012736817	3.957344e-01	5.395282e-01	5	16685738	16685831	94	-	1.493	1.581	0.301
ENSG00000145555	E018	38.780113	0.0006715134	1.120787e-01	2.085876e-01	5	16689824	16689919	96	-	1.516	1.642	0.433
ENSG00000145555	E019	55.445607	0.0095600674	4.971154e-01	6.336639e-01	5	16694371	16694614	244	-	1.699	1.779	0.272
ENSG00000145555	E020	36.894706	0.0053086940	8.364038e-01	8.976761e-01	5	16699450	16699573	124	-	1.557	1.580	0.076
ENSG00000145555	E021	105.032787	0.0003199199	1.359447e-01	2.424087e-01	5	16700963	16701838	876	-	2.026	2.012	-0.049
ENSG00000145555	E022	16.836886	0.0010934702	3.184547e-02	7.555547e-02	5	16702543	16702588	46	-	1.319	1.178	-0.497
ENSG00000145555	E023	17.960127	0.0015428183	6.861206e-04	2.848703e-03	5	16702925	16702976	52	-	1.389	1.150	-0.841
ENSG00000145555	E024	15.511061	0.0013958400	2.235962e-04	1.064607e-03	5	16702977	16702998	22	-	1.346	1.063	-1.005
ENSG00000145555	E025	13.142983	0.0016222696	6.756660e-03	2.059149e-02	5	16702999	16702999	1	-	1.253	1.038	-0.768
ENSG00000145555	E026	31.212238	0.0006315532	3.177996e-05	1.879563e-04	5	16703000	16703158	159	-	1.613	1.392	-0.759
ENSG00000145555	E027	29.279364	0.0007556915	4.993892e-02	1.090605e-01	5	16704579	16704685	107	-	1.520	1.430	-0.309
ENSG00000145555	E028	0.000000				5	16710672	16710703	32	-
ENSG00000145555	E029	0.147249	0.0431905043	4.381581e-01		5	16710704	16710907	204	-	0.124	0.000	-8.986
ENSG00000145555	E030	26.504550	0.0034315178	1.784024e-01	2.991405e-01	5	16710908	16711014	107	-	1.460	1.399	-0.208
ENSG00000145555	E031	11.550155	0.0347578492	7.175229e-01	8.128819e-01	5	16711015	16711022	8	-	1.089	1.082	-0.024
ENSG00000145555	E032	1.066342	0.3815697054	9.703035e-01	9.854139e-01	5	16711080	16711120	41	-	0.299	0.302	0.016
ENSG00000145555	E033	17.617155	0.0011864256	7.564487e-01	8.415266e-01	5	16711121	16711159	39	-	1.253	1.262	0.034
ENSG00000145555	E034	25.975742	0.0147152291	4.439342e-02	9.909510e-02	5	16711160	16711245	86	-	1.494	1.355	-0.477
ENSG00000145555	E035	0.000000				5	16713330	16713468	139	-
ENSG00000145555	E036	0.000000				5	16738136	16738398	263	-
ENSG00000145555	E037	0.000000				5	16738399	16738414	16	-
ENSG00000145555	E038	0.000000				5	16741804	16742228	425	-
ENSG00000145555	E039	26.117973	0.0132404942	4.019859e-03	1.319753e-02	5	16754828	16754908	81	-	1.529	1.316	-0.733
ENSG00000145555	E040	29.473650	0.0060972408	2.620723e-03	9.129305e-03	5	16758118	16758226	109	-	1.565	1.383	-0.626
ENSG00000145555	E041	27.087305	0.0008613510	6.270008e-04	2.632086e-03	5	16761464	16761546	83	-	1.541	1.351	-0.656
ENSG00000145555	E042	25.948409	0.0008945672	1.631336e-03	6.061383e-03	5	16762045	16762113	69	-	1.516	1.338	-0.612
ENSG00000145555	E043	30.398231	0.0007103439	1.858767e-03	6.785189e-03	5	16762545	16762637	93	-	1.573	1.414	-0.545
ENSG00000145555	E044	30.024649	0.0025789895	9.726582e-07	8.089344e-06	5	16763481	16763547	67	-	1.624	1.332	-1.002
ENSG00000145555	E045	25.680630	0.0069015055	1.030731e-08	1.267239e-07	5	16763655	16763755	101	-	1.606	1.188	-1.452
ENSG00000145555	E046	31.031808	0.0006855455	3.090526e-06	2.305355e-05	5	16764250	16764396	147	-	1.624	1.369	-0.874
ENSG00000145555	E047	28.171082	0.0012330591	4.477716e-05	2.552553e-04	5	16766080	16766198	119	-	1.577	1.345	-0.800
ENSG00000145555	E048	26.421000	0.0021819316	2.153882e-02	5.472507e-02	5	16769074	16769203	130	-	1.498	1.375	-0.423
ENSG00000145555	E049	21.377440	0.0010044132	1.052582e-02	3.003812e-02	5	16779545	16779648	104	-	1.423	1.269	-0.535
ENSG00000145555	E050	19.339855	0.0163071985	1.040229e-02	2.975290e-02	5	16780524	16780608	85	-	1.406	1.191	-0.754
ENSG00000145555	E051	9.659610	0.0022830816	2.686629e-03	9.334002e-03	5	16780728	16780733	6	-	1.154	0.869	-1.049
ENSG00000145555	E052	9.514438	0.0020278703	3.762652e-03	1.247634e-02	5	16780734	16780741	8	-	1.143	0.869	-1.012
ENSG00000145555	E053	22.714608	0.0008736746	2.310331e-09	3.202497e-08	5	16781705	16781829	125	-	1.545	1.140	-1.414
ENSG00000145555	E054	22.965679	0.0008139903	9.421622e-10	1.403773e-08	5	16783335	16783469	135	-	1.553	1.140	-1.442
ENSG00000145555	E055	24.205858	0.0009910428	6.663001e-07	5.748374e-06	5	16794646	16794833	188	-	1.545	1.230	-1.092
ENSG00000145555	E056	4.057891	0.0089608355	4.559544e-01	5.964302e-01	5	16814517	16815463	947	-	0.600	0.740	0.592
ENSG00000145555	E057	19.107270	0.0113287149	1.025696e-02	2.939846e-02	5	16818009	16818167	159	-	1.395	1.198	-0.689
ENSG00000145555	E058	17.120882	0.0011514822	5.176306e-05	2.905157e-04	5	16877609	16877707	99	-	1.395	1.097	-1.049
ENSG00000145555	E059	0.000000				5	16916055	16916527	473	-
ENSG00000145555	E060	30.963064	0.0202299741	1.140417e-05	7.480127e-05	5	16935788	16936288	501	-	1.666	1.301	-1.255

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000145555

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3