ENSG00000142102

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000397660 ENSG00000142102 HEK293_OSMI2_2hA HEK293_TMG_2hB PGGHG protein_coding protein_coding 6.105991 5.425712 5.116048 0.7661116 0.2016804 -0.08462189 0.07324466 0.2584496 0.000000 0.20173665 0.00000000 -4.7465792 0.01352083 0.05953333 0.0000000 -0.05953333 2.590513e-01 3.938665e-11 FALSE TRUE
ENST00000409479 ENSG00000142102 HEK293_OSMI2_2hA HEK293_TMG_2hB PGGHG protein_coding protein_coding 6.105991 5.425712 5.116048 0.7661116 0.2016804 -0.08462189 0.95428080 0.8246556 1.053146 0.24862641 0.12793219 0.3490870 0.15530000 0.14550000 0.2062667 0.06076667 4.348665e-01 3.938665e-11 FALSE TRUE
ENST00000474221 ENSG00000142102 HEK293_OSMI2_2hA HEK293_TMG_2hB PGGHG protein_coding retained_intron 6.105991 5.425712 5.116048 0.7661116 0.2016804 -0.08462189 1.51165370 0.9298094 1.323878 0.18796874 0.09480265 0.5051869 0.24475833 0.17146667 0.2597333 0.08826667 2.320425e-01 3.938665e-11 TRUE TRUE
ENST00000476372 ENSG00000142102 HEK293_OSMI2_2hA HEK293_TMG_2hB PGGHG protein_coding retained_intron 6.105991 5.425712 5.116048 0.7661116 0.2016804 -0.08462189 1.27253155 1.2595325 0.762439 0.14057736 0.17836643 -0.7168044 0.20874583 0.23433333 0.1486333 -0.08570000 2.292664e-01 3.938665e-11 FALSE TRUE
ENST00000529087 ENSG00000142102 HEK293_OSMI2_2hA HEK293_TMG_2hB PGGHG protein_coding retained_intron 6.105991 5.425712 5.116048 0.7661116 0.2016804 -0.08462189 1.52977835 0.9855073 1.400623 0.40172419 0.16644567 0.5028283 0.24677083 0.18223333 0.2723667 0.09013333 5.066658e-01 3.938665e-11 FALSE TRUE
MSTRG.4864.4 ENSG00000142102 HEK293_OSMI2_2hA HEK293_TMG_2hB PGGHG protein_coding   6.105991 5.425712 5.116048 0.7661116 0.2016804 -0.08462189 0.10241285 0.5978284 0.000000 0.02862228 0.00000000 -5.9255921 0.01935417 0.11320000 0.0000000 -0.11320000 3.938665e-11 3.938665e-11 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000142102 E001 0.1451727 0.0426636524 0.436873480   11 289120 289125 6 + 0.128 0.000 -9.648
ENSG00000142102 E002 0.5181333 0.0199520757 0.495373721 0.632188141 11 289126 289133 8 + 0.226 0.117 -1.139
ENSG00000142102 E003 0.6998377 0.0172566016 0.900204928 0.940319924 11 289134 289134 1 + 0.226 0.210 -0.139
ENSG00000142102 E004 2.9152493 0.0575582288 0.289349272 0.430033354 11 289135 289158 24 + 0.433 0.650 1.020
ENSG00000142102 E005 3.0635425 0.0411051605 0.197665378 0.323299314 11 289159 289167 9 + 0.433 0.677 1.136
ENSG00000142102 E006 3.0635425 0.0411051605 0.197665378 0.323299314 11 289168 289170 3 + 0.433 0.677 1.136
ENSG00000142102 E007 3.0635425 0.0411051605 0.197665378 0.323299314 11 289171 289171 1 + 0.433 0.677 1.136
ENSG00000142102 E008 3.2107915 0.0103075732 0.263461489 0.401370191 11 289172 289172 1 + 0.484 0.675 0.863
ENSG00000142102 E009 3.9041978 0.0042415642 0.063505712 0.132532445 11 289173 289177 5 + 0.484 0.775 1.275
ENSG00000142102 E010 5.8521824 0.0176826789 0.151014601 0.263039822 11 289178 289225 48 + 0.677 0.896 0.871
ENSG00000142102 E011 4.2602343 0.0166936913 0.295188560 0.436319135 11 289226 289239 14 + 0.610 0.776 0.692
ENSG00000142102 E012 22.4252527 0.0096476704 0.340815707 0.484747115 11 289559 289794 236 + 1.397 1.328 -0.240
ENSG00000142102 E013 10.6798620 0.0049327565 0.400053481 0.543773188 11 289795 289803 9 + 1.089 1.014 -0.273
ENSG00000142102 E014 19.4837194 0.0019760927 0.264018344 0.401963170 11 289804 289869 66 + 1.333 1.257 -0.263
ENSG00000142102 E015 18.7901107 0.0012763245 0.259668795 0.397112274 11 289870 289919 50 + 1.319 1.242 -0.269
ENSG00000142102 E016 29.2153338 0.0012057032 0.181573344 0.303212295 11 289920 290075 156 + 1.507 1.432 -0.255
ENSG00000142102 E017 31.8505895 0.0028035791 0.030536741 0.073021987 11 290390 290600 211 + 1.571 1.443 -0.438
ENSG00000142102 E018 13.2561700 0.1140802751 0.502915669 0.638920767 11 290601 290657 57 + 1.185 1.112 -0.262
ENSG00000142102 E019 11.2359507 0.0758197653 0.523768348 0.657402375 11 290658 290677 20 + 1.123 1.045 -0.283
ENSG00000142102 E020 24.5005169 0.0462337338 0.487311739 0.624983385 11 290678 290781 104 + 1.441 1.370 -0.248
ENSG00000142102 E021 33.9455618 0.0006428894 0.408827427 0.552437104 11 290782 290963 182 + 1.546 1.510 -0.125
ENSG00000142102 E022 18.5369406 0.0082492716 0.158558305 0.273198018 11 290964 291001 38 + 1.326 1.222 -0.365
ENSG00000142102 E023 30.1204892 0.0205037608 0.011234161 0.031724624 11 291002 291113 112 + 1.583 1.382 -0.690
ENSG00000142102 E024 31.1370810 0.0168011610 0.003927747 0.012939968 11 291114 291559 446 + 1.620 1.385 -0.806
ENSG00000142102 E025 23.4809604 0.0008809203 0.134948698 0.241021438 11 291560 291975 416 + 1.425 1.332 -0.325
ENSG00000142102 E026 30.7146415 0.0054068231 0.562048983 0.689743699 11 291976 292095 120 + 1.497 1.474 -0.080
ENSG00000142102 E027 37.4582121 0.0007297138 0.898734516 0.939415911 11 292546 292677 132 + 1.563 1.582 0.066
ENSG00000142102 E028 28.4584945 0.0007566916 0.684623968 0.787568657 11 292886 292983 98 + 1.436 1.475 0.132
ENSG00000142102 E029 13.5385344 0.0021383378 0.667345356 0.774625180 11 292984 292997 14 + 1.124 1.175 0.181
ENSG00000142102 E030 8.9993179 0.0021837306 0.850372205 0.907178930 11 292998 293067 70 + 0.995 0.986 -0.034
ENSG00000142102 E031 11.4552755 0.0231469432 0.526122589 0.659396165 11 293068 293162 95 + 1.010 1.114 0.379
ENSG00000142102 E032 22.1670395 0.0009406708 0.448010791 0.589352011 11 293163 293235 73 + 1.311 1.379 0.236
ENSG00000142102 E033 16.5204778 0.0011703065 0.225159183 0.356608550 11 293236 293365 130 + 1.156 1.271 0.407
ENSG00000142102 E034 35.5533385 0.0006474541 0.344030550 0.488085759 11 293366 293502 137 + 1.511 1.579 0.231
ENSG00000142102 E035 17.8156452 0.0010053214 0.794171108 0.868472653 11 293503 293573 71 + 1.266 1.257 -0.032
ENSG00000142102 E036 14.7038135 0.0012251383 0.870339230 0.920605216 11 293574 293593 20 + 1.186 1.184 -0.009
ENSG00000142102 E037 36.0874388 0.0006302398 0.124845498 0.226906557 11 293594 293669 76 + 1.598 1.522 -0.260
ENSG00000142102 E038 19.2025266 0.0010180263 0.111133552 0.207211365 11 293670 293678 9 + 1.353 1.241 -0.390
ENSG00000142102 E039 31.7059576 0.0007505185 0.724439193 0.817948923 11 293679 293727 49 + 1.502 1.493 -0.032
ENSG00000142102 E040 35.3870412 0.0006244028 0.396565628 0.540319385 11 293830 293925 96 + 1.563 1.526 -0.126
ENSG00000142102 E041 45.6405044 0.0005419369 0.674140357 0.779655867 11 294099 294196 98 + 1.634 1.668 0.117
ENSG00000142102 E042 24.1505179 0.0051958970 0.076708540 0.154228737 11 294267 294320 54 + 1.289 1.444 0.537
ENSG00000142102 E043 50.3512268 0.0119250611 0.456585174 0.596981234 11 294321 294478 158 + 1.654 1.728 0.249
ENSG00000142102 E044 176.6584902 0.0117710841 0.001136834 0.004426833 11 294556 296107 1552 + 2.120 2.316 0.654