ENSG00000141867

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-5 / 5
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000263377	ENSG00000141867	HEK293_OSMI2_2hA	HEK293_TMG_2hB	BRD4	protein_coding	protein_coding	28.49727	33.65777	25.45478	2.105876	0.5723249	-0.4028648	3.745712	9.92624042	0.000000	0.36886512	0.00000000	-9.9565563	0.1196958	0.2963000	0.0000000	-0.2963000	1.464545e-68	6.323618e-69	FALSE	TRUE
ENST00000371835	ENSG00000141867	HEK293_OSMI2_2hA	HEK293_TMG_2hB	BRD4	protein_coding	protein_coding	28.49727	33.65777	25.45478	2.105876	0.5723249	-0.4028648	9.382898	15.35443632	5.001148	0.94206696	0.10532957	-1.6163819	0.3158917	0.4564000	0.1967333	-0.2596667	2.451966e-26	6.323618e-69	FALSE	TRUE
ENST00000679869	ENSG00000141867	HEK293_OSMI2_2hA	HEK293_TMG_2hB	BRD4	protein_coding	protein_coding	28.49727	33.65777	25.45478	2.105876	0.5723249	-0.4028648	6.562158	5.92448868	6.836503	0.93135695	0.06034671	0.2062435	0.2293042	0.1750333	0.2687333	0.0937000	2.747624e-02	6.323618e-69	FALSE	TRUE
MSTRG.16611.10	ENSG00000141867	HEK293_OSMI2_2hA	HEK293_TMG_2hB	BRD4	protein_coding		28.49727	33.65777	25.45478	2.105876	0.5723249	-0.4028648	1.943440	0.00000000	3.597463	0.00000000	0.41119128	8.4948409	0.0767000	0.0000000	0.1409333	0.1409333	5.844617e-35	6.323618e-69	FALSE	TRUE
MSTRG.16611.7	ENSG00000141867	HEK293_OSMI2_2hA	HEK293_TMG_2hB	BRD4	protein_coding		28.49727	33.65777	25.45478	2.105876	0.5723249	-0.4028648	2.479661	0.02095915	5.323408	0.02095915	0.08668672	7.4285478	0.0969125	0.0006000	0.2092333	0.2086333	6.323618e-69	6.323618e-69	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 58
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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000141867	E001	568.9552497	0.0070107061	8.265904e-21	5.832219e-19	19	15235519	15237081	1563	-	2.404	2.844	1.467
ENSG00000141867	E002	233.6905374	0.0039934823	8.028084e-37	2.249847e-34	19	15237082	15237284	203	-	1.893	2.478	1.957
ENSG00000141867	E003	117.0567020	0.0087087940	7.750690e-09	9.752557e-08	19	15237285	15237350	66	-	1.772	2.151	1.271
ENSG00000141867	E004	138.2226490	0.0037150520	2.453366e-05	1.491362e-04	19	15237351	15237389	39	-	1.969	2.186	0.728
ENSG00000141867	E005	257.5321755	0.0030931340	3.788685e-10	6.066219e-09	19	15237390	15237566	177	-	2.206	2.465	0.864
ENSG00000141867	E006	184.9469536	0.0016468821	7.674113e-08	7.969727e-07	19	15237567	15237674	108	-	2.093	2.308	0.719
ENSG00000141867	E007	226.1570932	0.0018873330	1.639915e-07	1.598626e-06	19	15237675	15237890	216	-	2.189	2.392	0.678
ENSG00000141867	E008	424.6897083	0.0028612163	7.309837e-02	1.484862e-01	19	15237891	15238445	555	-	2.546	2.634	0.294
ENSG00000141867	E009	224.8125875	0.0014839189	6.614995e-01	7.699436e-01	19	15238743	15238980	238	-	2.317	2.333	0.054
ENSG00000141867	E010	279.1147977	0.0007445026	1.350948e-01	2.412232e-01	19	15239059	15239264	206	-	2.428	2.419	-0.030
ENSG00000141867	E011	226.8415166	0.0010166221	3.215801e-02	7.616250e-02	19	15239392	15239522	131	-	2.352	2.320	-0.106
ENSG00000141867	E012	169.9185031	0.0020502349	4.663817e-02	1.031879e-01	19	15239659	15239821	163	-	2.232	2.192	-0.135
ENSG00000141867	E013	109.9317197	0.0042445898	6.394811e-02	1.332700e-01	19	15239910	15240022	113	-	2.055	1.999	-0.186
ENSG00000141867	E014	66.7415506	0.0035364934	4.652394e-03	1.496455e-02	19	15242900	15243038	139	-	1.877	1.759	-0.398
ENSG00000141867	E015	2.8241275	0.0081991040	9.748443e-01	9.883351e-01	19	15243039	15243107	69	-	0.535	0.560	0.116
ENSG00000141867	E016	3.2075875	0.0048379145	1.563893e-02	4.193200e-02	19	15243108	15243221	114	-	0.796	0.453	-1.518
ENSG00000141867	E017	58.1380824	0.0010790683	2.399248e-02	5.979402e-02	19	15243222	15243487	266	-	1.798	1.715	-0.281
ENSG00000141867	E018	71.3448987	0.0003728700	1.158419e-03	4.499971e-03	19	15244231	15244522	292	-	1.904	1.793	-0.375
ENSG00000141867	E019	32.4792248	0.0143473184	2.348366e-02	5.874521e-02	19	15244523	15244600	78	-	1.604	1.445	-0.545
ENSG00000141867	E020	0.7665478	0.0197782430	5.790942e-02	1.230486e-01	19	15244601	15244709	109	-	0.418	0.101	-2.624
ENSG00000141867	E021	46.8820983	0.0007644834	3.973404e-04	1.764077e-03	19	15244710	15244762	53	-	1.757	1.600	-0.535
ENSG00000141867	E022	4.0338587	0.0055961113	3.100804e-01	4.524462e-01	19	15244763	15244998	236	-	0.767	0.644	-0.511
ENSG00000141867	E023	1.9208024	0.1056838879	6.500560e-01	7.611555e-01	19	15246508	15246618	111	-	0.480	0.414	-0.339
ENSG00000141867	E024	79.6862214	0.0265581315	1.896457e-04	9.197639e-04	19	15247047	15247276	230	-	1.600	1.989	1.315
ENSG00000141867	E025	768.8889737	0.0012327437	4.021381e-32	7.821751e-30	19	15247277	15248793	1517	-	2.663	2.944	0.934
ENSG00000141867	E026	83.7739733	0.0003600085	3.291587e-01	4.726643e-01	19	15248794	15248823	30	-	1.863	1.930	0.226
ENSG00000141867	E027	168.1365585	0.0002118796	4.117291e-02	9.320544e-02	19	15248824	15249004	181	-	2.145	2.232	0.291
ENSG00000141867	E028	88.3722221	0.0028923134	9.529778e-02	1.833291e-01	19	15249005	15249061	57	-	1.856	1.963	0.362
ENSG00000141867	E029	172.8971337	0.0026800639	3.837108e-03	1.268357e-02	19	15249062	15249290	229	-	2.121	2.260	0.465
ENSG00000141867	E030	12.4257546	0.0016736434	2.837040e-01	4.238578e-01	19	15252992	15253750	759	-	1.156	1.079	-0.277
ENSG00000141867	E031	2.9548049	0.0050665526	3.012941e-01	4.430900e-01	19	15253751	15253783	33	-	0.666	0.526	-0.625
ENSG00000141867	E032	8.9623225	0.0150318339	1.430207e-02	3.891484e-02	19	15253784	15254151	368	-	1.131	0.864	-0.989
ENSG00000141867	E033	208.3079892	0.0002076790	1.785357e-02	4.682103e-02	19	15254152	15254262	111	-	2.320	2.286	-0.110
ENSG00000141867	E034	362.6020417	0.0014133333	4.277030e-07	3.834692e-06	19	15255297	15255592	296	-	2.601	2.500	-0.335
ENSG00000141867	E035	118.6385686	0.0150207966	2.645539e-02	6.485957e-02	19	15256064	15256098	35	-	2.136	2.007	-0.432
ENSG00000141867	E036	103.5475788	0.0307735798	1.022681e-01	1.939727e-01	19	15256099	15256134	36	-	2.084	1.946	-0.463
ENSG00000141867	E037	124.4859470	0.0121163264	1.064619e-04	5.517560e-04	19	15256135	15256207	73	-	2.206	1.991	-0.722
ENSG00000141867	E038	116.4114981	0.0075631231	2.063400e-04	9.911635e-04	19	15256208	15256263	56	-	2.151	1.980	-0.573
ENSG00000141867	E039	252.9855342	0.0062480058	1.965066e-02	5.074091e-02	19	15256964	15257173	210	-	2.426	2.356	-0.233
ENSG00000141867	E040	1.5478668	0.0090233174	3.208719e-01	4.640452e-01	19	15257174	15258201	1028	-	0.257	0.452	1.182
ENSG00000141867	E041	2.9703443	0.0078776171	8.276385e-01	8.916477e-01	19	15258889	15259793	905	-	0.535	0.590	0.252
ENSG00000141867	E042	248.7015802	0.0006232507	3.919775e-14	1.180775e-12	19	15263420	15263548	129	-	2.471	2.309	-0.540
ENSG00000141867	E043	0.3332198	0.0295666121	7.174578e-01		19	15264118	15264403	286	-	0.147	0.101	-0.625
ENSG00000141867	E044	328.7319224	0.0001870033	8.611845e-30	1.421157e-27	19	15264404	15264766	363	-	2.614	2.413	-0.667
ENSG00000141867	E045	186.9258274	0.0009360183	3.411733e-09	4.582689e-08	19	15265354	15265626	273	-	2.341	2.195	-0.488
ENSG00000141867	E046	89.4664753	0.0023023700	1.236131e-06	1.006668e-05	19	15265627	15265643	17	-	2.045	1.862	-0.613
ENSG00000141867	E047	167.0677380	0.0031228735	7.771353e-09	9.776609e-08	19	15267416	15267513	98	-	2.315	2.125	-0.636
ENSG00000141867	E048	136.7552371	0.0124346608	3.585129e-04	1.612976e-03	19	15267514	15267551	38	-	2.226	2.043	-0.612
ENSG00000141867	E049	18.3062760	0.0225257303	4.135720e-02	9.354552e-02	19	15268154	15268240	87	-	1.381	1.193	-0.659
ENSG00000141867	E050	8.9886133	0.0018741908	6.654743e-04	2.772400e-03	19	15268241	15268281	41	-	1.169	0.830	-1.253
ENSG00000141867	E051	194.3764444	0.0054151885	1.562657e-10	2.667273e-09	19	15268905	15269012	108	-	2.411	2.165	-0.823
ENSG00000141867	E052	114.3836050	0.0003514098	3.728042e-18	1.912964e-16	19	15269013	15269042	30	-	2.191	1.926	-0.888
ENSG00000141867	E053	4.2168133	0.0066102490	8.660799e-04	3.494776e-03	19	15271322	15271392	71	-	0.939	0.491	-1.874
ENSG00000141867	E054	212.3570422	0.0010593302	6.779749e-23	5.954581e-21	19	15272815	15273133	319	-	2.452	2.200	-0.843
ENSG00000141867	E055	0.0000000				19	15275657	15275839	183	-
ENSG00000141867	E056	0.1472490	0.0432815601	3.032967e-01		19	15280264	15280451	188	-	0.147	0.000	-9.183
ENSG00000141867	E057	3.3086486	0.0046625469	8.444499e-01	9.031853e-01	19	15331836	15331907	72	-	0.627	0.617	-0.040
ENSG00000141867	E058	27.4376664	0.0007101765	2.242929e-13	6.071966e-12	19	15332290	15332579	290	-	1.669	1.210	-1.586

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000141867

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3