• ENSG00000140451
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000140451

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000268043 ENSG00000140451 HEK293_OSMI2_2hA HEK293_TMG_2hB PIF1 protein_coding protein_coding 8.733031 7.822868 5.722281 1.266383 0.446296 -0.4504313 2.1557949 3.14335938 0.6330726 0.26291373 0.31734288 -2.29383600 0.24814167 0.411066667 0.11090000 -0.30016667 0.237148205 0.001336076 FALSE  
ENST00000558380 ENSG00000140451 HEK293_OSMI2_2hA HEK293_TMG_2hB PIF1 protein_coding retained_intron 8.733031 7.822868 5.722281 1.266383 0.446296 -0.4504313 0.7646242 0.98566104 0.4476365 0.62021862 0.30335607 -1.12145267 0.07477083 0.111666667 0.07116667 -0.04050000 0.932978422 0.001336076 TRUE  
ENST00000558547 ENSG00000140451 HEK293_OSMI2_2hA HEK293_TMG_2hB PIF1 protein_coding retained_intron 8.733031 7.822868 5.722281 1.266383 0.446296 -0.4504313 0.5835231 0.06563289 0.5058581 0.06563289 0.12570839 2.76988864 0.06507083 0.009766667 0.09273333 0.08296667 0.063676925 0.001336076    
ENST00000559239 ENSG00000140451 HEK293_OSMI2_2hA HEK293_TMG_2hB PIF1 protein_coding protein_coding 8.733031 7.822868 5.722281 1.266383 0.446296 -0.4504313 0.5827196 0.14459812 0.7689671 0.07378797 0.37684655 2.33303963 0.06345833 0.017766667 0.13633333 0.11856667 0.126742807 0.001336076 FALSE  
ENST00000559522 ENSG00000140451 HEK293_OSMI2_2hA HEK293_TMG_2hB PIF1 protein_coding retained_intron 8.733031 7.822868 5.722281 1.266383 0.446296 -0.4504313 0.9634531 0.70336958 0.7432428 0.05016453 0.15970968 0.07846531 0.11079583 0.094433333 0.12723333 0.03280000 0.606073402 0.001336076    
ENST00000560444 ENSG00000140451 HEK293_OSMI2_2hA HEK293_TMG_2hB PIF1 protein_coding retained_intron 8.733031 7.822868 5.722281 1.266383 0.446296 -0.4504313 1.3549502 0.85400551 1.0821963 0.10123147 0.16201443 0.33811976 0.15505417 0.111800000 0.18726667 0.07546667 0.105776999 0.001336076 FALSE  
ENST00000560504 ENSG00000140451 HEK293_OSMI2_2hA HEK293_TMG_2hB PIF1 protein_coding retained_intron 8.733031 7.822868 5.722281 1.266383 0.446296 -0.4504313 0.5898466 0.43051445 0.7782752 0.11107167 0.06004432 0.83950995 0.07282917 0.054000000 0.13603333 0.08203333 0.001336076 0.001336076 FALSE  
MSTRG.11034.8 ENSG00000140451 HEK293_OSMI2_2hA HEK293_TMG_2hB PIF1 protein_coding   8.733031 7.822868 5.722281 1.266383 0.446296 -0.4504313 1.0580978 0.98242788 0.4771802 0.42310087 0.07480480 -1.02650673 0.12526667 0.115700000 0.08610000 -0.02960000 0.762328403 0.001336076    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_2hBColumn filter
HEK293_OSMI2_2hAColumn filter
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hBColumn filter
ENSG00000140451 E001 16.980780 0.0012134075 1.967109e-01 3.221415e-01 15 64815632 64815719 88 - 1.126 1.237 0.398
ENSG00000140451 E002 38.215517 0.0018484354 4.750729e-01 6.138310e-01 15 64815720 64815874 155 - 1.516 1.556 0.137
ENSG00000140451 E003 39.883958 0.0037683948 8.807869e-01 9.275546e-01 15 64815875 64815948 74 - 1.564 1.569 0.017
ENSG00000140451 E004 36.620648 0.0052601106 2.453075e-01 3.803886e-01 15 64815949 64816033 85 - 1.477 1.552 0.259
ENSG00000140451 E005 35.878978 0.0006511732 2.654696e-01 4.035241e-01 15 64816034 64816114 81 - 1.470 1.534 0.221
ENSG00000140451 E006 31.336456 0.0007173538 4.893967e-01 6.268278e-01 15 64816115 64816206 92 - 1.433 1.474 0.138
ENSG00000140451 E007 42.537758 0.0015808180 1.907275e-01 3.146643e-01 15 64816207 64816357 151 - 1.529 1.603 0.254
ENSG00000140451 E008 35.720322 0.0007350757 1.348674e-01 2.409193e-01 15 64816574 64816651 78 - 1.441 1.532 0.312
ENSG00000140451 E009 39.483380 0.0007254326 3.062608e-01 4.484211e-01 15 64816652 64816765 114 - 1.516 1.572 0.191
ENSG00000140451 E010 25.118563 0.0062284248 7.306941e-01 8.225410e-01 15 64817946 64818009 64 - 1.359 1.382 0.080
ENSG00000140451 E011 25.772703 0.0007544336 4.376084e-01 5.795273e-01 15 64818010 64818091 82 - 1.341 1.392 0.177
ENSG00000140451 E012 28.645810 0.0072691389 6.726296e-01 7.785265e-01 15 64818257 64818344 88 - 1.402 1.428 0.089
ENSG00000140451 E013 13.580083 0.0036152203 6.451402e-02 1.342368e-01 15 64818345 64818824 480 - 1.234 1.052 -0.653
ENSG00000140451 E014 4.005364 0.0595057688 5.882611e-01 7.114602e-01 15 64819037 64819116 80 - 0.722 0.620 -0.431
ENSG00000140451 E015 33.301337 0.0101895787 1.277369e-01 2.310093e-01 15 64819117 64819223 107 - 1.402 1.518 0.399
ENSG00000140451 E016 40.683387 0.0129074711 6.433344e-02 1.339213e-01 15 64819847 64819986 140 - 1.463 1.606 0.491
ENSG00000140451 E017 13.437786 0.0027437148 4.954544e-01 6.322503e-01 15 64819987 64820019 33 - 1.059 1.123 0.233
ENSG00000140451 E018 29.759250 0.0007866270 3.043637e-01 4.463680e-01 15 64820982 64821066 85 - 1.385 1.451 0.226
ENSG00000140451 E019 16.386258 0.0048299606 5.085130e-01 6.439159e-01 15 64821067 64821088 22 - 1.141 1.198 0.204
ENSG00000140451 E020 6.515191 0.0485445747 6.316513e-02 1.319853e-01 15 64821089 64821166 78 - 1.021 0.723 -1.149
ENSG00000140451 E021 32.062324 0.0009884213 3.945601e-01 5.383845e-01 15 64821167 64821281 115 - 1.426 1.477 0.178
ENSG00000140451 E022 10.443714 0.0018944111 1.854975e-01 3.081275e-01 15 64821282 64821366 85 - 1.110 0.966 -0.526
ENSG00000140451 E023 29.152891 0.0008021709 2.787447e-01 4.184118e-01 15 64821367 64821520 154 - 1.377 1.447 0.243
ENSG00000140451 E024 35.738794 0.0125116480 2.303471e-04 1.093110e-03 15 64821590 64822265 676 - 1.707 1.422 -0.973
ENSG00000140451 E025 18.618606 0.0023331714 4.046951e-01 5.483944e-01 15 64822266 64822337 72 - 1.301 1.226 -0.265
ENSG00000140451 E026 18.901458 0.0012026587 8.722588e-01 9.218524e-01 15 64822338 64822391 54 - 1.246 1.254 0.027
ENSG00000140451 E027 8.726830 0.0020447950 1.935382e-02 5.010075e-02 15 64822392 64822477 86 - 1.110 0.846 -0.980
ENSG00000140451 E028 18.119821 0.0346878578 7.108758e-01 8.079557e-01 15 64822478 64822610 133 - 1.269 1.215 -0.188
ENSG00000140451 E029 16.898831 0.0024793870 6.153630e-13 1.562926e-11 15 64823266 64823777 512 - 1.541 0.934 -2.152
ENSG00000140451 E030 27.726054 0.0167720492 8.168261e-02 1.621903e-01 15 64823778 64824354 577 - 1.510 1.354 -0.537
ENSG00000140451 E031 1.028791 0.0132265637 3.767867e-01 5.211023e-01 15 64825569 64825592 24 - 0.385 0.223 -1.090
ENSG00000140451 E032 7.878252 0.0027445990 6.245195e-01 7.408149e-01 15 64825593 64825668 76 - 0.856 0.911 0.209