ENSG00000139629

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000543196 ENSG00000139629 HEK293_OSMI2_2hA HEK293_TMG_2hB GALNT6 protein_coding protein_coding 2.835381 3.07652 2.91564 0.1917686 0.0520168 -0.07722884 1.79311594 2.40980275 1.4475439 0.05891406 0.19088496 -0.7313501 0.63269583 0.788133333 0.4980 -0.29013333 2.101705e-02 2.566377e-09 FALSE TRUE
ENST00000604506 ENSG00000139629 HEK293_OSMI2_2hA HEK293_TMG_2hB GALNT6 protein_coding protein_coding 2.835381 3.07652 2.91564 0.1917686 0.0520168 -0.07722884 0.17816377 0.00000000 0.4257442 0.00000000 0.01263291 5.4454096 0.06191667 0.000000000 0.1461 0.14610000 2.566377e-09 2.566377e-09   FALSE
MSTRG.7317.1 ENSG00000139629 HEK293_OSMI2_2hA HEK293_TMG_2hB GALNT6 protein_coding   2.835381 3.07652 2.91564 0.1917686 0.0520168 -0.07722884 0.36161779 0.25815102 0.4168088 0.10292391 0.21739621 0.6705442 0.12840833 0.081966667 0.1422 0.06023333 9.459361e-01 2.566377e-09 FALSE TRUE
MSTRG.7317.6 ENSG00000139629 HEK293_OSMI2_2hA HEK293_TMG_2hB GALNT6 protein_coding   2.835381 3.07652 2.91564 0.1917686 0.0520168 -0.07722884 0.08474657 0.01091802 0.1681763 0.01091802 0.16817630 3.0904872 0.02783333 0.003933333 0.0557 0.05176667 9.069948e-01 2.566377e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000139629 E001 0.0000000       12 51351247 51351251 5 -      
ENSG00000139629 E002 177.9537035 0.0022283226 8.872150e-11 1.579555e-09 12 51351252 51353768 2517 - 2.109 2.311 0.676
ENSG00000139629 E003 40.0578346 0.0082336458 8.959235e-01 9.374796e-01 12 51353769 51354134 366 - 1.598 1.596 -0.006
ENSG00000139629 E004 20.5504339 0.0010527384 7.456900e-01 8.336652e-01 12 51354135 51354212 78 - 1.295 1.329 0.119
ENSG00000139629 E005 18.9357829 0.0010715620 7.129487e-01 8.095249e-01 12 51354213 51354270 58 - 1.261 1.300 0.135
ENSG00000139629 E006 33.5066744 0.0014095645 2.188952e-01 3.490719e-01 12 51354271 51354492 222 - 1.564 1.499 -0.222
ENSG00000139629 E007 26.7037952 0.0113868006 3.850366e-01 5.291974e-01 12 51355806 51355958 153 - 1.469 1.408 -0.213
ENSG00000139629 E008 19.5232123 0.0024193039 3.178440e-01 4.607472e-01 12 51357349 51357450 102 - 1.342 1.274 -0.239
ENSG00000139629 E009 18.7922559 0.0235960108 1.782729e-01 2.989710e-01 12 51358130 51358261 132 - 1.364 1.237 -0.442
ENSG00000139629 E010 21.7531763 0.0051737837 9.656970e-02 1.852173e-01 12 51359132 51359332 201 - 1.423 1.304 -0.413
ENSG00000139629 E011 1.3359761 0.0099565018 3.226353e-02 7.635895e-02 12 51359333 51360226 894 - 0.559 0.194 -2.217
ENSG00000139629 E012 17.9322726 0.0046425209 3.818074e-02 8.769536e-02 12 51360721 51360838 118 - 1.364 1.203 -0.566
ENSG00000139629 E013 24.2497617 0.0008851243 1.009008e-01 1.918422e-01 12 51364121 51364355 235 - 1.458 1.357 -0.352
ENSG00000139629 E014 17.4275925 0.0139176972 7.865160e-01 8.632906e-01 12 51365430 51365579 150 - 1.261 1.242 -0.066
ENSG00000139629 E015 18.9264693 0.0069721306 8.312151e-01 8.942031e-01 12 51377195 51377367 173 - 1.287 1.276 -0.038
ENSG00000139629 E016 13.4087376 0.0071578304 6.803871e-01 7.842809e-01 12 51379291 51379369 79 - 1.161 1.129 -0.115
ENSG00000139629 E017 12.3581010 0.0015175557 8.859178e-01 9.310409e-01 12 51379370 51379412 43 - 1.114 1.110 -0.015
ENSG00000139629 E018 17.5103637 0.0011200740 4.301710e-01 5.728074e-01 12 51379413 51379545 133 - 1.287 1.233 -0.190
ENSG00000139629 E019 9.1107012 0.0019327624 8.466203e-01 9.046766e-01 12 51379546 51379575 30 - 0.983 1.014 0.112
ENSG00000139629 E020 10.1049221 0.0017168251 7.467783e-01 8.344441e-01 12 51379576 51379593 18 - 1.016 1.059 0.157
ENSG00000139629 E021 9.6901312 0.0030740772 7.214808e-01 8.158486e-01 12 51379594 51379615 22 - 1.000 1.047 0.175
ENSG00000139629 E022 12.3527152 0.0015242863 8.552873e-01 9.105330e-01 12 51379616 51379663 48 - 1.101 1.128 0.097
ENSG00000139629 E023 10.9791764 0.0015625883 6.226375e-01 7.394107e-01 12 51379664 51379711 48 - 1.031 1.090 0.213
ENSG00000139629 E024 7.2600018 0.0024451635 3.187440e-01 4.617172e-01 12 51379712 51379712 1 - 0.821 0.950 0.493
ENSG00000139629 E025 13.7608969 0.0013614405 9.613831e-01 9.796843e-01 12 51379713 51379785 73 - 1.150 1.155 0.018
ENSG00000139629 E026 9.5999396 0.0103707729 4.956478e-01 6.324229e-01 12 51379786 51379812 27 - 1.046 0.978 -0.251
ENSG00000139629 E027 8.5377384 0.0170295263 2.826420e-01 4.226712e-01 12 51379813 51379840 28 - 1.031 0.908 -0.458
ENSG00000139629 E028 8.4121747 0.0020097640 1.005337e-01 1.912603e-01 12 51379841 51379884 44 - 1.061 0.891 -0.630
ENSG00000139629 E029 1.4091281 0.0096765512 3.256136e-02 7.692546e-02 12 51382313 51382334 22 - 0.559 0.195 -2.215
ENSG00000139629 E030 3.5376868 0.0046056336 1.636185e-02 4.352416e-02 12 51382335 51382460 126 - 0.821 0.474 -1.507
ENSG00000139629 E031 2.6530242 0.0058381441 8.346050e-04 3.382539e-03 12 51382461 51382509 49 - 0.796 0.267 -2.629
ENSG00000139629 E032 7.4416732 0.0022696659 1.077167e-01 2.021686e-01 12 51383461 51383491 31 - 1.016 0.841 -0.659
ENSG00000139629 E033 9.2173320 0.0019399227 2.805321e-02 6.812013e-02 12 51383492 51383582 91 - 1.126 0.906 -0.809
ENSG00000139629 E034 2.6475327 0.0058240458 3.656874e-01 5.099875e-01 12 51390850 51390937 88 - 0.459 0.613 0.729
ENSG00000139629 E035 1.1748942 0.1264107088 9.657639e-01 9.824732e-01 12 51391082 51391195 114 - 0.327 0.329 0.014
ENSG00000139629 E036 0.8459408 0.0155639018 9.123004e-01 9.484211e-01 12 51391196 51391286 91 - 0.243 0.267 0.178
ENSG00000139629 E037 0.8909922 0.0224733307 2.983477e-01 4.397842e-01 12 51391287 51391354 68 - 0.138 0.329 1.592
ENSG00000139629 E038 0.3729606 0.0302797531 8.253406e-01 8.900071e-01 12 51391355 51391591 237 - 0.138 0.108 -0.406
ENSG00000139629 E039 5.2671472 0.0045998225 2.588184e-02 6.369965e-02 12 51391601 51391955 355 - 0.948 0.669 -1.102
ENSG00000139629 E040 0.0000000       12 51392791 51392867 77 -