ENSG00000135387

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-5 / 5
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000341394	ENSG00000135387	HEK293_OSMI2_2hA	HEK293_TMG_2hB	CAPRIN1	protein_coding	protein_coding	74.74	41.68149	111.5096	5.28359	4.477229	1.419473	31.631127	13.413518	46.09581542	2.1910745	2.40232051	1.780186	0.4297292	0.32493333	0.4134333	0.08850000	4.037497e-01	4.870493e-12	FALSE	TRUE
ENST00000530820	ENSG00000135387	HEK293_OSMI2_2hA	HEK293_TMG_2hB	CAPRIN1	protein_coding	protein_coding	74.74	41.68149	111.5096	5.28359	4.477229	1.419473	13.503856	5.602102	22.38630349	0.8210341	0.84183001	1.996647	0.1639333	0.13440000	0.2008333	0.06643333	2.843250e-04	4.870493e-12	FALSE	TRUE
ENST00000531668	ENSG00000135387	HEK293_OSMI2_2hA	HEK293_TMG_2hB	CAPRIN1	protein_coding	processed_transcript	74.74	41.68149	111.5096	5.28359	4.477229	1.419473	1.543402	4.078626	0.00000000	3.5035452	0.00000000	-8.675472	0.0315250	0.08133333	0.0000000	-0.08133333	9.864383e-02	4.870493e-12	FALSE	FALSE
ENST00000532820	ENSG00000135387	HEK293_OSMI2_2hA	HEK293_TMG_2hB	CAPRIN1	protein_coding	protein_coding	74.74	41.68149	111.5096	5.28359	4.477229	1.419473	19.517865	9.822290	31.23645907	1.9976085	0.90016049	1.668093	0.2552583	0.24226667	0.2807000	0.03843333	7.601216e-01	4.870493e-12	FALSE	TRUE
ENST00000533657	ENSG00000135387	HEK293_OSMI2_2hA	HEK293_TMG_2hB	CAPRIN1	protein_coding	processed_transcript	74.74	41.68149	111.5096	5.28359	4.477229	1.419473	1.598510	6.529281	0.09646978	2.5215013	0.05122661	-5.940616	0.0409875	0.16210000	0.0009000	-0.16120000	1.464389e-05	4.870493e-12	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 42
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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000135387	E001	46.1740403	4.631635e-03	2.256402e-08	2.605087e-07	11	34051382	34051730	349	+	1.697	1.364	-1.141
ENSG00000135387	E002	46.0352103	3.687455e-03	1.160253e-08	1.414092e-07	11	34051731	34051731	1	+	1.696	1.364	-1.135
ENSG00000135387	E003	75.8304539	2.211177e-03	5.391865e-15	1.846146e-13	11	34051732	34051750	19	+	1.912	1.542	-1.256
ENSG00000135387	E004	121.2168416	5.389535e-04	1.861713e-31	3.454417e-29	11	34051751	34051871	121	+	2.122	1.684	-1.475
ENSG00000135387	E005	0.0000000				11	34052033	34052054	22	+
ENSG00000135387	E006	0.0000000				11	34052055	34052162	108	+
ENSG00000135387	E007	29.8207510	1.398983e-02	4.628875e-02	1.025597e-01	11	34052210	34052328	119	+	1.467	1.355	-0.388
ENSG00000135387	E008	116.9427340	1.914103e-03	8.140469e-10	1.226959e-08	11	34052329	34052420	92	+	2.068	1.872	-0.657
ENSG00000135387	E009	573.4589785	5.752909e-03	2.768618e-16	1.127971e-14	11	34052421	34052636	216	+	2.768	2.505	-0.874
ENSG00000135387	E010	3.6889617	1.517966e-01	6.578588e-01	7.671448e-01	11	34052637	34052867	231	+	0.591	0.711	0.514
ENSG00000135387	E011	2.2037885	6.769588e-03	9.223248e-01	9.549787e-01	11	34052981	34053185	205	+	0.449	0.523	0.364
ENSG00000135387	E012	0.5891098	1.826087e-02	2.394010e-01	3.734264e-01	11	34053451	34053519	69	+	0.237	0.000	-10.113
ENSG00000135387	E013	0.6234514	5.351509e-01	9.467114e-01	9.705478e-01	11	34053522	34053671	150	+	0.189	0.201	0.111
ENSG00000135387	E014	0.0000000				11	34055686	34055737	52	+
ENSG00000135387	E015	0.0000000				11	34055738	34055740	3	+
ENSG00000135387	E016	0.0000000				11	34055741	34055805	65	+
ENSG00000135387	E017	0.3289534	2.974504e-02	4.736481e-01		11	34056486	34056571	86	+	0.072	0.200	1.686
ENSG00000135387	E018	0.1515154	4.385383e-02	1.000000e+00		11	34063052	34063363	312	+	0.072	0.000	-8.114
ENSG00000135387	E019	449.8140900	7.044809e-04	1.902072e-36	5.147741e-34	11	34071726	34071788	63	+	2.656	2.433	-0.746
ENSG00000135387	E020	528.2775030	5.702091e-04	6.810843e-24	6.692395e-22	11	34071901	34071987	87	+	2.708	2.574	-0.447
ENSG00000135387	E021	870.1381958	7.652130e-03	5.128206e-05	2.881832e-04	11	34076236	34076474	239	+	2.916	2.813	-0.344
ENSG00000135387	E022	475.5215420	6.564835e-03	2.982666e-03	1.021194e-02	11	34076560	34076642	83	+	2.642	2.592	-0.170
ENSG00000135387	E023	659.4665771	3.861465e-03	8.916814e-06	5.998379e-05	11	34079628	34079765	138	+	2.790	2.715	-0.249
ENSG00000135387	E024	469.4690079	9.944580e-04	1.802038e-14	5.717478e-13	11	34082825	34082877	53	+	2.651	2.545	-0.353
ENSG00000135387	E025	567.3546907	1.666603e-04	3.600811e-23	3.253042e-21	11	34082955	34083041	87	+	2.731	2.636	-0.316
ENSG00000135387	E026	669.1203928	1.600883e-04	1.384376e-23	1.308059e-21	11	34086064	34086219	156	+	2.799	2.717	-0.275
ENSG00000135387	E027	626.2969772	1.265189e-04	1.957395e-14	6.174204e-13	11	34086305	34086413	109	+	2.762	2.718	-0.144
ENSG00000135387	E028	567.0458702	1.493845e-04	9.960789e-11	1.758004e-09	11	34089395	34089456	62	+	2.715	2.685	-0.098
ENSG00000135387	E029	2.0464109	7.940322e-02	3.816491e-01	5.259534e-01	11	34090026	34090178	153	+	0.477	0.337	-0.768
ENSG00000135387	E030	722.0788023	1.208244e-04	3.530232e-09	4.726111e-08	11	34090179	34090289	111	+	2.814	2.807	-0.021
ENSG00000135387	E031	806.4341407	8.911456e-05	1.746629e-02	4.596894e-02	11	34090529	34090678	150	+	2.845	2.896	0.169
ENSG00000135387	E032	2.3542467	1.272257e-02	5.214623e-01	6.553329e-01	11	34091619	34091905	287	+	0.502	0.440	-0.313
ENSG00000135387	E033	790.4678407	3.317162e-04	2.785406e-02	6.772770e-02	11	34091906	34092056	151	+	2.815	2.932	0.390
ENSG00000135387	E034	1.3619978	9.894440e-03	1.803336e-01	3.015886e-01	11	34095819	34095851	33	+	0.237	0.523	1.687
ENSG00000135387	E035	5.3063349	3.956704e-02	1.956099e-01	3.207319e-01	11	34096160	34096478	319	+	0.666	0.934	1.060
ENSG00000135387	E036	693.1682357	1.427984e-04	2.734434e-02	6.669632e-02	11	34096479	34096592	114	+	2.759	2.876	0.391
ENSG00000135387	E037	464.3711976	2.279435e-03	6.169570e-01	7.348878e-01	11	34096593	34096629	37	+	2.592	2.685	0.309
ENSG00000135387	E038	518.2268963	5.480059e-03	6.486912e-01	7.601542e-01	11	34096630	34096673	44	+	2.638	2.731	0.309
ENSG00000135387	E039	706.1498776	4.863752e-04	1.048449e-01	1.978654e-01	11	34097196	34097296	101	+	2.768	2.879	0.370
ENSG00000135387	E040	591.0389078	4.905541e-04	4.046563e-02	9.187686e-02	11	34097698	34097761	64	+	2.688	2.810	0.405
ENSG00000135387	E041	255.1277887	6.742101e-03	4.391548e-07	3.928257e-06	11	34097762	34099058	1297	+	2.248	2.568	1.066
ENSG00000135387	E042	4366.2108342	4.476516e-03	1.324796e-21	1.011603e-19	11	34099303	34102610	3308	+	3.480	3.794	1.045

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000135387

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3