ENSG00000134324

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-5 / 5
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000256720	ENSG00000134324	HEK293_OSMI2_2hA	HEK293_TMG_2hB	LPIN1	protein_coding	protein_coding	5.273891	4.491996	5.616478	0.5264861	0.2341904	0.3216671	2.5305412	1.6054903	3.0500719	0.05855747	0.2890459	0.9215935	0.47172500	0.36450000	0.5417333	0.1772333	3.498985e-02	3.020139e-33	FALSE	TRUE
ENST00000460096	ENSG00000134324	HEK293_OSMI2_2hA	HEK293_TMG_2hB	LPIN1	protein_coding	retained_intron	5.273891	4.491996	5.616478	0.5264861	0.2341904	0.3216671	0.4754421	0.2813486	0.4953068	0.14075787	0.2645913	0.7944134	0.08813333	0.07040000	0.0885000	0.0181000	9.877441e-01	3.020139e-33		FALSE
ENST00000475286	ENSG00000134324	HEK293_OSMI2_2hA	HEK293_TMG_2hB	LPIN1	protein_coding	processed_transcript	5.273891	4.491996	5.616478	0.5264861	0.2341904	0.3216671	0.6758960	0.4116201	1.2109021	0.21724298	0.1721778	1.5339317	0.11897083	0.08233333	0.2153000	0.1329667	4.130832e-01	3.020139e-33		FALSE
ENST00000487576	ENSG00000134324	HEK293_OSMI2_2hA	HEK293_TMG_2hB	LPIN1	protein_coding	processed_transcript	5.273891	4.491996	5.616478	0.5264861	0.2341904	0.3216671	0.7023582	1.6936617	0.0000000	0.17099071	0.0000000	-7.4124951	0.15258333	0.37893333	0.0000000	-0.3789333	3.020139e-33	3.020139e-33	FALSE	FALSE
ENST00000674199	ENSG00000134324	HEK293_OSMI2_2hA	HEK293_TMG_2hB	LPIN1	protein_coding	protein_coding	5.273891	4.491996	5.616478	0.5264861	0.2341904	0.3216671	0.4751578	0.2087167	0.6616510	0.10973534	0.1907821	1.6186488	0.08816667	0.04286667	0.1201667	0.0773000	2.929916e-01	3.020139e-33	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 52
Columns:
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groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000134324	E001	0.0000000				2	11677595	11677728	134	+
ENSG00000134324	E002	0.0000000				2	11713756	11713812	57	+
ENSG00000134324	E003	0.0000000				2	11724334	11724348	15	+
ENSG00000134324	E004	0.0000000				2	11724349	11724349	1	+
ENSG00000134324	E005	0.0000000				2	11724350	11724351	2	+
ENSG00000134324	E006	0.0000000				2	11724352	11724539	188	+
ENSG00000134324	E007	0.0000000				2	11724540	11724642	103	+
ENSG00000134324	E008	0.0000000				2	11741349	11741428	80	+
ENSG00000134324	E009	0.0000000				2	11742015	11742151	137	+
ENSG00000134324	E010	0.0000000				2	11745907	11745960	54	+
ENSG00000134324	E011	0.0000000				2	11745961	11746130	170	+
ENSG00000134324	E012	1.0329332	0.1226309991	2.196984e-02	5.561008e-02	2	11746588	11746631	44	+	0.475	0.000	-13.144
ENSG00000134324	E013	1.0329332	0.1226309991	2.196984e-02	5.561008e-02	2	11746632	11746633	2	+	0.475	0.000	-15.251
ENSG00000134324	E014	1.1844487	0.0593808592	8.607349e-03	2.530629e-02	2	11746634	11746637	4	+	0.515	0.000	-15.654
ENSG00000134324	E015	6.7816843	0.0617962213	2.194233e-02	5.555583e-02	2	11746638	11746671	34	+	1.038	0.640	-1.561
ENSG00000134324	E016	0.5848540	0.1282148593	5.654507e-02	1.206698e-01	2	11755799	11755864	66	+	0.000	0.329	13.589
ENSG00000134324	E017	1.1468953	0.0113985141	9.993846e-01	1.000000e+00	2	11763023	11763286	264	+	0.329	0.326	-0.019
ENSG00000134324	E018	0.0000000				2	11764204	11764289	86	+
ENSG00000134324	E019	15.3640195	0.0656999361	8.809346e-03	2.580766e-02	2	11765533	11765733	201	+	1.364	0.962	-1.436
ENSG00000134324	E020	15.7529093	0.0012564620	3.580230e-03	1.195526e-02	2	11767763	11767858	96	+	1.331	1.073	-0.916
ENSG00000134324	E021	30.1354710	0.0006928780	9.278202e-04	3.712359e-03	2	11771372	11771679	308	+	1.585	1.369	-0.742
ENSG00000134324	E022	18.4803780	0.0010392915	2.179743e-02	5.525319e-02	2	11773620	11773745	126	+	1.369	1.181	-0.660
ENSG00000134324	E023	3.5274579	0.0097808668	1.023637e-01	1.941249e-01	2	11776086	11776193	108	+	0.765	0.510	-1.109
ENSG00000134324	E024	0.1451727	0.0429387962	6.477571e-01		2	11777207	11777521	315	+	0.108	0.000	-12.913
ENSG00000134324	E025	20.9551475	0.0010080343	1.361815e-03	5.182640e-03	2	11779519	11779645	127	+	1.442	1.192	-0.873
ENSG00000134324	E026	26.6603630	0.0055859360	5.065198e-02	1.103163e-01	2	11782201	11782363	163	+	1.512	1.361	-0.519
ENSG00000134324	E027	26.6556773	0.0007575109	1.836770e-01	3.058168e-01	2	11782364	11782507	144	+	1.488	1.396	-0.319
ENSG00000134324	E028	15.0677239	0.0012321501	6.312623e-01	7.462947e-01	2	11783829	11783868	40	+	1.228	1.181	-0.164
ENSG00000134324	E029	15.3998708	0.0012558357	9.581277e-01	9.777472e-01	2	11783869	11783922	54	+	1.213	1.212	-0.001
ENSG00000134324	E030	4.2145930	0.0135249155	6.103908e-01	7.297119e-01	2	11783923	11784313	391	+	0.671	0.740	0.284
ENSG00000134324	E031	5.3831591	0.0031212316	7.679242e-01	8.500452e-01	2	11784712	11784885	174	+	0.786	0.820	0.133
ENSG00000134324	E032	25.0250913	0.0009962987	2.357706e-01	3.692904e-01	2	11784886	11785076	191	+	1.455	1.369	-0.298
ENSG00000134324	E033	0.0000000				2	11787047	11787073	27	+
ENSG00000134324	E034	12.3041742	0.0014785478	6.401193e-01	7.534135e-01	2	11787074	11787129	56	+	1.148	1.099	-0.174
ENSG00000134324	E035	11.1971360	0.0016540553	1.896226e-01	3.132776e-01	2	11787130	11787167	38	+	1.148	1.014	-0.484
ENSG00000134324	E036	16.2392519	0.0258859791	2.046702e-01	3.319791e-01	2	11788387	11788456	70	+	1.301	1.157	-0.510
ENSG00000134324	E037	0.0000000				2	11791708	11791785	78	+
ENSG00000134324	E038	22.9600738	0.0008699795	2.569343e-02	6.330445e-02	2	11791914	11792006	93	+	1.451	1.285	-0.574
ENSG00000134324	E039	0.0000000				2	11792007	11792349	343	+
ENSG00000134324	E040	22.3534289	0.0008654985	7.965057e-01	8.701115e-01	2	11795408	11795487	80	+	1.385	1.362	-0.080
ENSG00000134324	E041	24.4347734	0.0009792895	7.287274e-01	8.211268e-01	2	11802907	11803033	127	+	1.424	1.396	-0.097
ENSG00000134324	E042	12.1985545	0.0014427523	8.076571e-01	8.777978e-01	2	11804423	11804427	5	+	1.139	1.112	-0.097
ENSG00000134324	E043	14.0357105	0.0013328811	7.062514e-01	8.044361e-01	2	11804428	11804439	12	+	1.197	1.159	-0.135
ENSG00000134324	E044	26.1796581	0.0007707264	6.841738e-01	7.871990e-01	2	11804440	11804571	132	+	1.428	1.451	0.077
ENSG00000134324	E045	19.8593341	0.0010259929	6.357074e-01	7.499129e-01	2	11805070	11805156	87	+	1.342	1.302	-0.142
ENSG00000134324	E046	0.9932018	0.0129571037	4.403897e-02	9.845702e-02	2	11805157	11805515	359	+	0.108	0.457	2.716
ENSG00000134324	E047	20.5965467	0.0009563878	9.727319e-01	9.870019e-01	2	11815088	11815240	153	+	1.342	1.340	-0.007
ENSG00000134324	E048	3.2847919	0.0048071594	6.553254e-01	7.652398e-01	2	11816153	11819483	3331	+	0.671	0.600	-0.305
ENSG00000134324	E049	25.5997530	0.0008056214	6.334347e-01	7.481447e-01	2	11819484	11819598	115	+	1.451	1.415	-0.124
ENSG00000134324	E050	24.6451577	0.0007921951	6.312540e-01	7.462947e-01	2	11820411	11820514	104	+	1.433	1.396	-0.129
ENSG00000134324	E051	0.2214452	0.0421409142	3.658797e-01		2	11823080	11823175	96	+	0.000	0.138	12.391
ENSG00000134324	E052	280.2134993	0.0002888858	9.164248e-25	9.803158e-23	2	11824632	11827409	2778	+	2.362	2.536	0.582

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000134324

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3