ENSG00000132466

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-6 / 6
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000330838	ENSG00000132466	HEK293_OSMI2_2hA	HEK293_TMG_2hB	ANKRD17	protein_coding	protein_coding	26.22049	19.71205	31.86087	3.619391	0.3451234	0.6924287	6.656512	4.7381563	6.905174	1.01268815	0.51161579	0.5423981	0.25467917	0.23870000	0.21680000	-0.0219000	7.316135e-01	5.2991e-11	FALSE	TRUE
ENST00000358602	ENSG00000132466	HEK293_OSMI2_2hA	HEK293_TMG_2hB	ANKRD17	protein_coding	protein_coding	26.22049	19.71205	31.86087	3.619391	0.3451234	0.6924287	1.908128	2.8812053	1.542515	0.05482775	0.04812623	-0.8970643	0.07995833	0.15756667	0.04843333	-0.1091333	4.771747e-04	5.2991e-11	FALSE	TRUE
ENST00000509867	ENSG00000132466	HEK293_OSMI2_2hA	HEK293_TMG_2hB	ANKRD17	protein_coding	protein_coding	26.22049	19.71205	31.86087	3.619391	0.3451234	0.6924287	5.423247	0.5768385	8.923508	0.35691606	0.61931023	3.9281915	0.19012500	0.03610000	0.27970000	0.2436000	4.831398e-02	5.2991e-11	FALSE	TRUE
ENST00000510127	ENSG00000132466	HEK293_OSMI2_2hA	HEK293_TMG_2hB	ANKRD17	protein_coding	processed_transcript	26.22049	19.71205	31.86087	3.619391	0.3451234	0.6924287	1.973314	3.9513450	0.000000	2.01312558	0.00000000	-8.6298465	0.09041250	0.17556667	0.00000000	-0.1755667	1.177942e-01	5.2991e-11		FALSE
ENST00000558247	ENSG00000132466	HEK293_OSMI2_2hA	HEK293_TMG_2hB	ANKRD17	protein_coding	protein_coding	26.22049	19.71205	31.86087	3.619391	0.3451234	0.6924287	6.120348	6.2762036	6.861331	0.97275443	0.52170919	0.1284006	0.24013750	0.32353333	0.21553333	-0.1080000	2.691211e-02	5.2991e-11	FALSE	TRUE
MSTRG.25018.12	ENSG00000132466	HEK293_OSMI2_2hA	HEK293_TMG_2hB	ANKRD17	protein_coding		26.22049	19.71205	31.86087	3.619391	0.3451234	0.6924287	1.845145	0.4574882	4.074058	0.06488401	0.20411329	3.1270017	0.06245000	0.02466667	0.12773333	0.1030667	5.299100e-11	5.2991e-11	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 55
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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
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width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000132466	E001	113.6288080	0.0111234998	1.363720e-17	6.578881e-16	4	73073376	73075237	1862	-	1.731	2.293	1.887
ENSG00000132466	E002	229.4717468	0.0056004880	2.983826e-27	3.944709e-25	4	73075238	73075685	448	-	2.077	2.576	1.666
ENSG00000132466	E003	134.7393886	0.0081130818	4.726177e-19	2.704198e-17	4	73075686	73075781	96	-	1.840	2.350	1.712
ENSG00000132466	E004	202.9959709	0.0063443907	1.936330e-22	1.621715e-20	4	73075782	73075855	74	-	2.039	2.519	1.604
ENSG00000132466	E005	602.6958942	0.0061409313	7.593659e-28	1.060911e-25	4	73075856	73076290	435	-	2.524	2.983	1.526
ENSG00000132466	E006	260.6559743	0.0030907501	1.204013e-24	1.270734e-22	4	73076940	73077104	165	-	2.210	2.593	1.277
ENSG00000132466	E007	135.1459003	0.0035769718	1.744194e-14	5.553484e-13	4	73077355	73077368	14	-	1.945	2.295	1.172
ENSG00000132466	E008	311.3705404	0.0019024383	3.284013e-24	3.334118e-22	4	73077369	73077533	165	-	2.324	2.645	1.070
ENSG00000132466	E009	345.9212846	0.0015812363	2.026436e-19	1.214496e-17	4	73078642	73078890	249	-	2.400	2.669	0.896
ENSG00000132466	E010	0.1472490	0.0433276866	7.461349e-01		4	73080721	73080810	90	-	0.097	0.000	-10.648
ENSG00000132466	E011	214.5423318	0.0012681310	3.333829e-14	1.015245e-12	4	73085249	73085365	117	-	2.203	2.455	0.841
ENSG00000132466	E012	168.1739431	0.0011003149	7.251708e-07	6.207927e-06	4	73085366	73085446	81	-	2.135	2.321	0.622
ENSG00000132466	E013	1148.5316382	0.0010388483	3.934775e-03	1.295929e-02	4	73090667	73092300	1634	-	3.019	3.099	0.268
ENSG00000132466	E014	175.8902906	0.0002030231	3.885397e-01	5.326171e-01	4	73094079	73094228	150	-	2.219	2.272	0.179
ENSG00000132466	E015	169.2524508	0.0003757087	5.548987e-02	1.188257e-01	4	73097117	73097272	156	-	2.236	2.211	-0.083
ENSG00000132466	E016	293.0987378	0.0004838823	2.778647e-01	4.174912e-01	4	73098073	73098520	448	-	2.461	2.466	0.017
ENSG00000132466	E017	2.0421565	0.0079744554	5.528683e-01	6.820997e-01	4	73100861	73101007	147	-	0.512	0.430	-0.413
ENSG00000132466	E018	4.7543996	0.0034714024	5.424494e-01	6.732094e-01	4	73101008	73101173	166	-	0.779	0.719	-0.243
ENSG00000132466	E019	96.6859266	0.0148118422	7.384777e-01	8.283492e-01	4	73102376	73102462	87	-	1.965	2.012	0.159
ENSG00000132466	E020	93.8191577	0.0055813230	6.396448e-01	7.529953e-01	4	73102463	73102547	85	-	1.971	1.976	0.015
ENSG00000132466	E021	2.1079336	0.0506050054	9.924332e-01	9.993541e-01	4	73102548	73102779	232	-	0.478	0.494	0.081
ENSG00000132466	E022	0.2214452	0.0448635601	3.121216e-01		4	73104003	73104080	78	-	0.000	0.154	10.837
ENSG00000132466	E023	10.6367086	0.0060296390	1.681237e-01	2.857576e-01	4	73112879	73112894	16	-	1.114	0.994	-0.438
ENSG00000132466	E024	33.3281289	0.0258091736	3.773798e-02	8.684490e-02	4	73112895	73113079	185	-	1.599	1.427	-0.592
ENSG00000132466	E025	12.4887246	0.0015699566	5.465942e-01	6.767528e-01	4	73113080	73113083	4	-	1.139	1.109	-0.108
ENSG00000132466	E026	49.0764835	0.0050090574	4.204452e-04	1.852762e-03	4	73113084	73113311	228	-	1.768	1.576	-0.651
ENSG00000132466	E027	154.2468690	0.0003807654	7.779983e-02	1.559446e-01	4	73113792	73113908	117	-	2.196	2.173	-0.077
ENSG00000132466	E028	143.3559269	0.0002122676	1.537276e-02	4.133418e-02	4	73115821	73115916	96	-	2.171	2.127	-0.148
ENSG00000132466	E029	184.8014288	0.0001879718	7.976664e-08	8.258581e-07	4	73118688	73118850	163	-	2.309	2.193	-0.389
ENSG00000132466	E030	187.3585486	0.0002183312	1.559282e-14	5.000022e-13	4	73120162	73120337	176	-	2.337	2.154	-0.610
ENSG00000132466	E031	210.3500428	0.0012197369	1.050338e-12	2.568190e-11	4	73120881	73121094	214	-	2.388	2.201	-0.625
ENSG00000132466	E032	204.1633993	0.0032841264	1.147779e-06	9.410280e-06	4	73121617	73121759	143	-	2.364	2.213	-0.505
ENSG00000132466	E033	186.2944664	0.0031109361	3.665863e-08	4.057293e-07	4	73124913	73125058	146	-	2.335	2.155	-0.600
ENSG00000132466	E034	172.8202077	0.0086882898	3.504381e-07	3.197642e-06	4	73125201	73125312	112	-	2.321	2.081	-0.803
ENSG00000132466	E035	171.1387155	0.0034160736	5.312655e-13	1.361378e-11	4	73135117	73135262	146	-	2.322	2.058	-0.883
ENSG00000132466	E036	55.0863636	0.0040415199	3.065148e-07	2.830529e-06	4	73135263	73135265	3	-	1.835	1.559	-0.935
ENSG00000132466	E037	248.6261114	0.0023030523	2.715985e-13	7.262318e-12	4	73139531	73140283	753	-	2.468	2.257	-0.703
ENSG00000132466	E038	109.3600074	0.0080749469	3.387384e-06	2.506855e-05	4	73141741	73141792	52	-	2.120	1.887	-0.782
ENSG00000132466	E039	107.9364021	0.0026982020	1.346510e-11	2.745881e-10	4	73141793	73141843	51	-	2.125	1.855	-0.908
ENSG00000132466	E040	153.8805827	0.0045706241	9.388194e-10	1.399233e-08	4	73142242	73142385	144	-	2.269	2.026	-0.813
ENSG00000132466	E041	131.3063822	0.0082007306	2.535273e-07	2.382203e-06	4	73142640	73142767	128	-	2.203	1.953	-0.835
ENSG00000132466	E042	106.6431002	0.0102557776	4.763282e-08	5.162116e-07	4	73144745	73144832	88	-	2.130	1.825	-1.023
ENSG00000132466	E043	118.7455906	0.0113324102	3.953257e-07	3.567535e-06	4	73146764	73146873	110	-	2.170	1.886	-0.952
ENSG00000132466	E044	147.8385372	0.0002849473	1.954859e-28	2.870869e-26	4	73147241	73147432	192	-	2.275	1.945	-1.105
ENSG00000132466	E045	176.6611674	0.0055126157	1.727775e-16	7.219272e-15	4	73148813	73149050	238	-	2.358	2.003	-1.187
ENSG00000132466	E046	114.8422361	0.0082053043	2.385947e-09	3.299829e-08	4	73151430	73151524	95	-	2.161	1.852	-1.035
ENSG00000132466	E047	161.2486926	0.0123760220	1.856235e-07	1.789611e-06	4	73153880	73154113	234	-	2.302	2.015	-0.960
ENSG00000132466	E048	146.9537633	0.0018300929	9.605221e-18	4.733820e-16	4	73155631	73155778	148	-	2.262	1.967	-0.990
ENSG00000132466	E049	148.3226510	0.0023134296	2.340654e-19	1.392682e-17	4	73156019	73156166	148	-	2.275	1.947	-1.098
ENSG00000132466	E050	128.0109924	0.0151368418	3.850141e-09	5.120736e-08	4	73161192	73161348	157	-	2.224	1.849	-1.256
ENSG00000132466	E051	0.4482035	0.0281251584	1.831470e-01	3.051408e-01	4	73168929	73169090	162	-	0.243	0.000	-12.489
ENSG00000132466	E052	104.7015382	0.0203393794	2.645831e-07	2.476383e-06	4	73177380	73177533	154	-	2.136	1.766	-1.245
ENSG00000132466	E053	3.5557755	0.0127139694	1.023924e-03	4.041183e-03	4	73222974	73223114	141	-	0.813	0.266	-2.705
ENSG00000132466	E054	43.0348240	0.0306511596	6.256914e-04	2.627405e-03	4	73258276	73258284	9	-	1.740	1.428	-1.066
ENSG00000132466	E055	101.4766983	0.0432662880	3.054284e-05	1.813871e-04	4	73258285	73258839	555	-	2.130	1.726	-1.358

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000132466

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3