ENSG00000132204

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000412816 ENSG00000132204 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.91239 1.144225 2.595493 0.09390389 0.2118257 1.174632 0.23804228 0.061371396 0.43443034 0.031279353 0.06707425 2.6385394 0.11936667 0.057200000 0.17376667 0.116566667 0.1440460934 0.0001171566   FALSE
ENST00000582570 ENSG00000132204 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.91239 1.144225 2.595493 0.09390389 0.2118257 1.174632 0.03180380 0.000000000 0.15529320 0.000000000 0.08299334 4.0469555 0.01299167 0.000000000 0.05963333 0.059633333 0.3643024920 0.0001171566   FALSE
ENST00000654559 ENSG00000132204 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.91239 1.144225 2.595493 0.09390389 0.2118257 1.174632 0.17000124 0.396808389 0.00000000 0.143730655 0.00000000 -5.3462775 0.09760417 0.357100000 0.00000000 -0.357100000 0.0001171566 0.0001171566   FALSE
ENST00000655957 ENSG00000132204 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.91239 1.144225 2.595493 0.09390389 0.2118257 1.174632 0.06563981 0.000000000 0.12767909 0.000000000 0.07865590 3.7832376 0.03479167 0.000000000 0.05360000 0.053600000 0.4646591776 0.0001171566   FALSE
ENST00000660358 ENSG00000132204 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.91239 1.144225 2.595493 0.09390389 0.2118257 1.174632 0.08651184 0.008797424 0.15405739 0.008797424 0.03303290 3.1255937 0.04240833 0.009066667 0.05956667 0.050500000 0.1311128867 0.0001171566   FALSE
ENST00000660475 ENSG00000132204 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.91239 1.144225 2.595493 0.09390389 0.2118257 1.174632 0.12369882 0.000000000 0.12262050 0.000000000 0.12262050 3.7292319 0.06807500 0.000000000 0.05546667 0.055466667 0.9561912535 0.0001171566   FALSE
ENST00000661233 ENSG00000132204 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.91239 1.144225 2.595493 0.09390389 0.2118257 1.174632 0.04203864 0.029614739 0.21666006 0.029614739 0.14704683 2.5164210 0.01617917 0.022966667 0.07940000 0.056433333 0.7593606172 0.0001171566   FALSE
ENST00000661931 ENSG00000132204 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.91239 1.144225 2.595493 0.09390389 0.2118257 1.174632 0.10585380 0.039882369 0.16545795 0.039882369 0.11154066 1.8145234 0.05144583 0.034000000 0.05906667 0.025066667 0.8465665127 0.0001171566   FALSE
ENST00000667416 ENSG00000132204 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.91239 1.144225 2.595493 0.09390389 0.2118257 1.174632 0.07527112 0.000000000 0.20753905 0.000000000 0.20753905 4.4432025 0.03533333 0.000000000 0.07876667 0.078766667 0.9444731081 0.0001171566   FALSE
ENST00000669153 ENSG00000132204 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.91239 1.144225 2.595493 0.09390389 0.2118257 1.174632 0.08827722 0.047721176 0.08568381 0.047721176 0.08568381 0.7291741 0.05766667 0.040666667 0.03250000 -0.008166667 0.9020400230 0.0001171566   FALSE
ENST00000669242 ENSG00000132204 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.91239 1.144225 2.595493 0.09390389 0.2118257 1.174632 0.13928150 0.243000266 0.11998782 0.018500762 0.09004124 -0.9607624 0.08705833 0.213066667 0.04470000 -0.168366667 0.0625232575 0.0001171566   FALSE
ENST00000669312 ENSG00000132204 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 1.91239 1.144225 2.595493 0.09390389 0.2118257 1.174632 0.07967153 0.025610761 0.19617597 0.025610761 0.09880246 2.5334911 0.02934167 0.019833333 0.07030000 0.050466667 0.6821302749 0.0001171566 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000132204 E001 0.0000000       18 1254383 1254386 4 -      
ENSG00000132204 E002 0.0000000       18 1254387 1254388 2 -      
ENSG00000132204 E003 1.2909221 0.010309206 0.29534418 0.43647764 18 1254389 1254581 193 - 0.289 0.446 0.924
ENSG00000132204 E004 0.3299976 0.027442404 0.06381207   18 1254582 1254582 1 - 0.000 0.278 15.431
ENSG00000132204 E005 0.4815130 0.020404730 0.22295369 0.35389882 18 1254583 1254596 14 - 0.092 0.278 1.923
ENSG00000132204 E006 6.5635183 0.024032920 0.09445926 0.18206907 18 1254597 1255214 618 - 0.792 0.977 0.708
ENSG00000132204 E007 2.2323831 0.042897032 0.11762644 0.21655742 18 1267497 1267548 52 - 0.610 0.277 -1.784
ENSG00000132204 E008 4.6437750 0.040581437 0.07263006 0.14772338 18 1268311 1269010 700 - 0.853 0.509 -1.461
ENSG00000132204 E009 1.7693041 0.008748523 0.23151640 0.36427434 18 1269011 1269175 165 - 0.527 0.278 -1.398
ENSG00000132204 E010 2.5412642 0.006935155 0.05301477 0.11451182 18 1269176 1269521 346 - 0.657 0.278 -1.982
ENSG00000132204 E011 1.0330470 0.012258390 0.04053611 0.09200265 18 1269522 1269522 1 - 0.424 0.000 -15.853
ENSG00000132204 E012 1.0330470 0.012258390 0.04053611 0.09200265 18 1269523 1269523 1 - 0.424 0.000 -15.853
ENSG00000132204 E013 1.0330470 0.012258390 0.04053611 0.09200265 18 1269524 1269524 1 - 0.424 0.000 -15.853
ENSG00000132204 E014 1.1782197 0.011650717 0.02603887 0.06402485 18 1269525 1269525 1 - 0.461 0.000 -16.028
ENSG00000132204 E015 1.1782197 0.011650717 0.02603887 0.06402485 18 1269526 1269526 1 - 0.461 0.000 -16.028
ENSG00000132204 E016 1.0267042 0.029730406 0.04312396 0.09677453 18 1269527 1269527 1 - 0.424 0.000 -15.849
ENSG00000132204 E017 1.0267042 0.029730406 0.04312396 0.09677453 18 1269528 1269528 1 - 0.424 0.000 -15.849
ENSG00000132204 E018 1.0267042 0.029730406 0.04312396 0.09677453 18 1269529 1269534 6 - 0.424 0.000 -15.849
ENSG00000132204 E019 0.8815316 0.014117483 0.06386346 0.13313022 18 1269535 1269537 3 - 0.383 0.000 -15.652
ENSG00000132204 E020 1.0277484 0.084213521 0.31509972 0.45785515 18 1269538 1269566 29 - 0.383 0.160 -1.665
ENSG00000132204 E021 1.5384062 0.018643077 0.89130678 0.93456534 18 1269567 1269583 17 - 0.424 0.370 -0.298
ENSG00000132204 E022 5.9753299 0.037710442 0.37925127 0.52352096 18 1269584 1269669 86 - 0.808 0.906 0.378
ENSG00000132204 E023 6.5634061 0.003669267 0.14486512 0.25465586 18 1269670 1269671 2 - 0.824 0.957 0.508
ENSG00000132204 E024 6.8632147 0.005735642 0.13157999 0.23633725 18 1269672 1269686 15 - 0.839 0.978 0.526
ENSG00000132204 E025 12.5169264 0.001703013 0.12728491 0.23035455 18 1269687 1269820 134 - 1.091 1.186 0.339
ENSG00000132204 E026 6.6677541 0.002700634 0.40103987 0.54471139 18 1269821 1269847 27 - 0.854 0.912 0.224
ENSG00000132204 E027 4.9735556 0.023603502 0.94469694 0.96929685 18 1269848 1269852 5 - 0.792 0.738 -0.215
ENSG00000132204 E028 0.0000000       18 1269853 1269935 83 -      
ENSG00000132204 E029 0.2934659 0.029836107 0.58109576   18 1271611 1271819 209 - 0.092 0.161 0.923
ENSG00000132204 E030 6.7116622 0.002706566 0.68494122 0.78776141 18 1272442 1272511 70 - 0.882 0.888 0.024
ENSG00000132204 E031 3.2870863 0.004838239 0.04789902 0.10544676 18 1273361 1273533 173 - 0.739 0.370 -1.739
ENSG00000132204 E032 10.7445639 0.001749117 0.23101129 0.36367893 18 1275966 1276077 112 - 1.029 1.102 0.268
ENSG00000132204 E033 0.8824740 0.245459390 0.54182874 0.67274511 18 1276078 1276087 10 - 0.232 0.362 0.879
ENSG00000132204 E034 0.4439371 0.021670910 0.28094746 0.42080813 18 1276088 1276647 560 - 0.233 0.000 -14.753
ENSG00000132204 E035 1.9218622 0.008131435 0.91722136 0.95170847 18 1278568 1278633 66 - 0.461 0.446 -0.075
ENSG00000132204 E036 0.0000000       18 1278634 1278651 18 -      
ENSG00000132204 E037 0.4396707 0.027970319 0.28271629 0.42274893 18 1278652 1279331 680 - 0.233 0.000 -14.752
ENSG00000132204 E038 1.4747915 0.011814491 0.92615893 0.95751037 18 1302717 1303760 1044 - 0.383 0.370 -0.073
ENSG00000132204 E039 0.9243042 0.014089402 0.36680487 0.51113689 18 1349150 1349621 472 - 0.233 0.370 0.923
ENSG00000132204 E040 0.3634088 0.300521828 0.10496417   18 1353407 1353462 56 - 0.000 0.279 15.287
ENSG00000132204 E041 7.6937138 0.003061711 0.04583368 0.10172751 18 1358726 1358760 35 - 0.854 1.036 0.683
ENSG00000132204 E042 7.5909099 0.002544662 0.01569633 0.04205615 18 1358761 1358894 134 - 0.824 1.053 0.863
ENSG00000132204 E043 0.5954526 0.018376049 0.16665505 0.28383933 18 1358895 1359058 164 - 0.289 0.000 -15.127
ENSG00000132204 E044 0.9286724 0.014183311 0.40265483 0.54642304 18 1359059 1359227 169 - 0.339 0.161 -1.397
ENSG00000132204 E045 0.4482035 0.028060952 0.28269600 0.42272526 18 1359228 1359386 159 - 0.233 0.000 -14.753
ENSG00000132204 E046 0.7447899 0.059460172 0.72781230 0.82040792 18 1359387 1359439 53 - 0.233 0.277 0.329
ENSG00000132204 E047 1.3371220 0.012561258 0.14620995 0.25653432 18 1359440 1359557 118 - 0.461 0.161 -2.076
ENSG00000132204 E048 1.1146300 0.033219446 0.85517764 0.91043411 18 1359558 1359590 33 - 0.339 0.278 -0.397
ENSG00000132204 E049 0.9599941 0.107189602 0.44927036 0.59046701 18 1359591 1359629 39 - 0.339 0.162 -1.386
ENSG00000132204 E050 0.9557277 0.021656730 0.40647970 0.55012009 18 1359630 1359650 21 - 0.339 0.161 -1.394
ENSG00000132204 E051 1.2481495 0.032097675 0.21630170 0.34595818 18 1359651 1360085 435 - 0.424 0.161 -1.878
ENSG00000132204 E052 0.2924217 0.027820898 0.50296442   18 1360086 1360213 128 - 0.168 0.000 -14.220
ENSG00000132204 E053 2.8118117 0.006047474 0.90196105 0.94154171 18 1361143 1361176 34 - 0.584 0.567 -0.076
ENSG00000132204 E054 5.9764085 0.018932844 0.30217874 0.44403224 18 1361177 1361221 45 - 0.792 0.888 0.374
ENSG00000132204 E055 2.6938198 0.006686765 0.32598901 0.46942922 18 1361736 1361834 99 - 0.495 0.617 0.564
ENSG00000132204 E056 1.0309706 0.029900285 0.04314514 0.09681172 18 1365917 1366103 187 - 0.424 0.000 -15.850
ENSG00000132204 E057 1.1845624 0.010948958 0.02600586 0.06395696 18 1366104 1366186 83 - 0.461 0.000 -16.028
ENSG00000132204 E058 0.4460135 0.025155003 0.28275416 0.42279221 18 1366187 1366225 39 - 0.233 0.000 -14.753
ENSG00000132204 E059 0.5922303 0.018094307 0.77345837 0.85384103 18 1366290 1366461 172 - 0.233 0.161 -0.662
ENSG00000132204 E060 0.5997190 0.141228742 0.20399192 0.33116807 18 1368089 1368289 201 - 0.289 0.000 -15.119
ENSG00000132204 E061 0.5997190 0.141228742 0.20399192 0.33116807 18 1368290 1368484 195 - 0.289 0.000 -15.119
ENSG00000132204 E062 10.7984723 0.014484986 0.11755154 0.21644268 18 1368485 1368597 113 - 1.009 1.132 0.448
ENSG00000132204 E063 0.0000000       18 1392086 1392185 100 -      
ENSG00000132204 E064 4.6940203 0.004340144 0.92268401 0.95523669 18 1406987 1406996 10 - 0.758 0.702 -0.226
ENSG00000132204 E065 8.9140413 0.019854202 0.93231850 0.96136133 18 1406997 1407053 57 - 0.999 0.939 -0.226
ENSG00000132204 E066 5.7085421 0.027905146 0.74412014 0.83256307 18 1407054 1407057 4 - 0.809 0.807 -0.007
ENSG00000132204 E067 6.5211735 0.029248946 0.88883196 0.93289980 18 1407058 1407078 21 - 0.868 0.837 -0.120
ENSG00000132204 E068 6.6557371 0.002998176 0.98047738 0.99176603 18 1407079 1407088 10 - 0.882 0.835 -0.181
ENSG00000132204 E069 8.4992504 0.002146932 0.78593891 0.86291717 18 1407089 1407169 81 - 0.989 0.913 -0.284
ENSG00000132204 E070 3.5095742 0.004763452 0.63786050 0.75165505 18 1407170 1407178 9 - 0.679 0.567 -0.489
ENSG00000132204 E071 3.1826971 0.004954251 0.50101481 0.63720664 18 1407179 1407180 2 - 0.657 0.511 -0.659
ENSG00000132204 E072 3.1826971 0.004954251 0.50101481 0.63720664 18 1407181 1407186 6 - 0.657 0.511 -0.659
ENSG00000132204 E073 2.9612519 0.005512295 0.29468284 0.43579843 18 1407187 1407188 2 - 0.657 0.446 -0.982
ENSG00000132204 E074 2.8160792 0.006200280 0.36626050 0.51059593 18 1407189 1407206 18 - 0.634 0.446 -0.882
ENSG00000132204 E075 0.6621732 0.043136657 0.46682587 0.60636376 18 1407207 1407211 5 - 0.168 0.278 0.926
ENSG00000132204 E076 0.4804688 0.020912824 1.00000000 1.00000000 18 1407212 1407212 1 - 0.168 0.161 -0.075
ENSG00000132204 E077 0.4804688 0.020912824 1.00000000 1.00000000 18 1407213 1407215 3 - 0.168 0.161 -0.075
ENSG00000132204 E078 0.2987644 0.026940305 0.50387642   18 1407216 1407216 1 - 0.168 0.000 -14.220
ENSG00000132204 E079 0.2987644 0.026940305 0.50387642   18 1407217 1407220 4 - 0.168 0.000 -14.220
ENSG00000132204 E080 0.2987644 0.026940305 0.50387642   18 1407221 1407228 8 - 0.168 0.000 -14.220
ENSG00000132204 E081 0.1515154 0.043100105 1.00000000   18 1407229 1407231 3 - 0.092 0.000 -13.292
ENSG00000132204 E082 0.0000000       18 1407232 1407234 3 -      
ENSG00000132204 E083 0.0000000       18 1407235 1407244 10 -      
ENSG00000132204 E084 0.0000000       18 1408247 1408344 98 -