ENSG00000130787

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-5 / 5
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000253083	ENSG00000130787	HEK293_OSMI2_2hA	HEK293_TMG_2hB	HIP1R	protein_coding	protein_coding	18.51469	26.64113	11.55374	1.180964	0.4847796	-1.204589	10.6717102	16.3227522	6.5443603	1.7357328	0.2412468	-1.3172410	0.57062917	0.61333333	0.56666667	-0.04666667	7.944406e-01	5.228334e-05	FALSE	TRUE
ENST00000452196	ENSG00000130787	HEK293_OSMI2_2hA	HEK293_TMG_2hB	HIP1R	protein_coding	retained_intron	18.51469	26.64113	11.55374	1.180964	0.4847796	-1.204589	1.2754263	0.8166872	1.0817948	0.1428079	0.0357721	0.4012884	0.07887500	0.03120000	0.09413333	0.06293333	5.342969e-04	5.228334e-05	FALSE	TRUE
ENST00000535012	ENSG00000130787	HEK293_OSMI2_2hA	HEK293_TMG_2hB	HIP1R	protein_coding	protein_coding	18.51469	26.64113	11.55374	1.180964	0.4847796	-1.204589	0.5071253	0.2835384	1.3089859	0.2835384	0.3540962	2.1678078	0.03618750	0.01096667	0.11140000	0.10043333	4.920945e-02	5.228334e-05	FALSE	TRUE
ENST00000536617	ENSG00000130787	HEK293_OSMI2_2hA	HEK293_TMG_2hB	HIP1R	protein_coding	retained_intron	18.51469	26.64113	11.55374	1.180964	0.4847796	-1.204589	3.8823705	7.3159714	0.9875057	1.2856308	0.1606154	-2.8766231	0.18822083	0.27160000	0.08483333	-0.18676667	7.439022e-05	5.228334e-05	FALSE	TRUE
ENST00000541712	ENSG00000130787	HEK293_OSMI2_2hA	HEK293_TMG_2hB	HIP1R	protein_coding	retained_intron	18.51469	26.64113	11.55374	1.180964	0.4847796	-1.204589	0.8160664	0.2894756	0.9807661	0.1616909	0.1415442	1.7261062	0.05286667	0.01103333	0.08593333	0.07490000	1.810761e-03	5.228334e-05	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000130787	E001	1.506035	0.0096540733	5.408497e-02	1.163975e-01	12	122834453	122835006	554	+	0.000	0.409	10.955
ENSG00000130787	E002	13.587359	0.0018342020	9.231749e-04	3.696114e-03	12	122835457	122835480	24	+	1.300	0.992	-1.104
ENSG00000130787	E003	56.677305	0.0004504638	6.795833e-06	4.694954e-05	12	122835481	122835643	163	+	1.840	1.622	-0.737
ENSG00000130787	E004	61.842885	0.0003936862	4.790199e-04	2.079584e-03	12	122848031	122848094	64	+	1.840	1.677	-0.550
ENSG00000130787	E005	94.102528	0.0003378076	1.010954e-08	1.244944e-07	12	122848466	122848608	143	+	2.055	1.838	-0.729
ENSG00000130787	E006	63.674193	0.0025362878	1.643005e-04	8.106003e-04	12	122848796	122848852	57	+	1.870	1.681	-0.639
ENSG00000130787	E007	65.333574	0.0004067559	3.804871e-03	1.259495e-02	12	122849875	122849955	81	+	1.840	1.709	-0.445
ENSG00000130787	E008	0.000000				12	122850806	122850834	29	+
ENSG00000130787	E009	64.221238	0.0005803209	2.544091e-01	3.910937e-01	12	122850835	122850911	77	+	1.770	1.720	-0.169
ENSG00000130787	E010	54.346801	0.0004542250	1.914996e-02	4.966179e-02	12	122851236	122851297	62	+	1.754	1.638	-0.393
ENSG00000130787	E011	4.268747	0.0037420342	2.398118e-06	1.833547e-05	12	122853483	122854042	560	+	1.052	0.409	-2.716
ENSG00000130787	E012	99.551866	0.0003673345	1.358523e-01	2.422835e-01	12	122854043	122854183	141	+	1.961	1.908	-0.178
ENSG00000130787	E013	76.431674	0.0040324934	9.573218e-01	9.772435e-01	12	122854905	122854962	58	+	1.797	1.811	0.047
ENSG00000130787	E014	42.953883	0.0082761547	6.719088e-01	7.780440e-01	12	122855053	122855058	6	+	1.532	1.576	0.150
ENSG00000130787	E015	73.389787	0.0040916495	8.412853e-01	9.009960e-01	12	122855059	122855128	70	+	1.774	1.796	0.075
ENSG00000130787	E016	106.838542	0.0073322824	4.987963e-01	6.351952e-01	12	122855265	122855405	141	+	1.976	1.950	-0.088
ENSG00000130787	E017	85.856171	0.0013711594	7.644528e-02	1.538137e-01	12	122855551	122855612	62	+	1.918	1.845	-0.245
ENSG00000130787	E018	91.868213	0.0006341242	3.828539e-02	8.788383e-02	12	122855831	122855903	73	+	1.951	1.871	-0.269
ENSG00000130787	E019	145.777599	0.0002322215	4.821194e-01	6.202832e-01	12	122855980	122856163	184	+	2.101	2.084	-0.055
ENSG00000130787	E020	105.273483	0.0003892053	6.374917e-01	7.513758e-01	12	122856256	122856344	89	+	1.929	1.955	0.089
ENSG00000130787	E021	127.985253	0.0002399591	7.976469e-01	8.708957e-01	12	122856432	122856548	117	+	2.019	2.035	0.056
ENSG00000130787	E022	111.713659	0.0002578908	6.441008e-01	7.564852e-01	12	122856625	122856726	102	+	1.953	1.978	0.085
ENSG00000130787	E023	118.366992	0.0011809082	7.195626e-01	8.143558e-01	12	122857021	122857215	195	+	1.976	2.000	0.078
ENSG00000130787	E024	29.037833	0.0044498331	5.509126e-08	5.882580e-07	12	122857216	122858017	802	+	1.667	1.287	-1.308
ENSG00000130787	E025	88.335311	0.0025490094	8.252329e-01	8.899167e-01	12	122858102	122858249	148	+	1.870	1.869	-0.003
ENSG00000130787	E026	76.600909	0.0060073148	7.941210e-01	8.684529e-01	12	122858349	122858435	87	+	1.790	1.817	0.091
ENSG00000130787	E027	1.253359	0.0124869601	4.608336e-03	1.484296e-02	12	122858825	122858837	13	+	0.628	0.143	-3.053
ENSG00000130787	E028	106.917390	0.0017275721	8.668344e-01	9.182874e-01	12	122858838	122858945	108	+	1.940	1.956	0.056
ENSG00000130787	E029	118.685484	0.0003177874	9.580468e-02	1.840948e-01	12	122859061	122859197	137	+	1.943	2.015	0.242
ENSG00000130787	E030	2.430431	0.0061381230	6.730380e-03	2.052230e-02	12	122859422	122859425	4	+	0.769	0.337	-2.053
ENSG00000130787	E031	120.919932	0.0002690387	5.584585e-01	6.866897e-01	12	122859426	122859536	111	+	1.986	2.015	0.098
ENSG00000130787	E032	103.531661	0.0002821278	3.990283e-01	5.427769e-01	12	122859772	122859830	59	+	1.909	1.951	0.140
ENSG00000130787	E033	2.829237	0.0054112152	7.701537e-01	8.515823e-01	12	122860038	122860046	9	+	0.569	0.525	-0.206
ENSG00000130787	E034	84.686922	0.0003493131	1.650564e-01	2.817726e-01	12	122860047	122860077	31	+	1.801	1.871	0.237
ENSG00000130787	E035	11.816045	0.0026328481	3.348221e-02	7.873667e-02	12	122860078	122860147	70	+	1.194	0.982	-0.765
ENSG00000130787	E036	71.497986	0.0027332788	2.930942e-02	7.060581e-02	12	122860148	122860164	17	+	1.682	1.813	0.442
ENSG00000130787	E037	96.194257	0.0073250786	4.079830e-02	9.250887e-02	12	122860165	122860210	46	+	1.805	1.939	0.451
ENSG00000130787	E038	5.953545	0.0103291658	9.746032e-05	5.101278e-04	12	122860211	122860329	119	+	1.111	0.615	-1.933
ENSG00000130787	E039	135.365565	0.0018186887	1.043186e-01	1.970644e-01	12	122860423	122860523	101	+	1.996	2.071	0.254
ENSG00000130787	E040	3.450251	0.0478060123	3.078023e-03	1.049536e-02	12	122860524	122860678	155	+	0.906	0.411	-2.163
ENSG00000130787	E041	155.557523	0.0021295277	1.251335e-01	2.273275e-01	12	122860679	122860784	106	+	2.059	2.131	0.238
ENSG00000130787	E042	168.476500	0.0044099076	3.412554e-01	4.851805e-01	12	122860916	122861039	124	+	2.108	2.163	0.186
ENSG00000130787	E043	111.146777	0.0003456932	5.634599e-01	6.909201e-01	12	122861131	122861192	62	+	1.981	1.966	-0.051
ENSG00000130787	E044	8.256307	0.0020578308	2.593235e-01	3.967026e-01	12	122861193	122861307	115	+	0.769	0.926	0.610
ENSG00000130787	E045	201.662606	0.0002269841	8.499625e-01	9.069104e-01	12	122861308	122861514	207	+	2.226	2.228	0.006
ENSG00000130787	E046	3.232486	0.0050024388	3.382554e-01	4.821231e-01	12	122861515	122861647	133	+	0.419	0.595	0.855
ENSG00000130787	E047	79.146135	0.0011510054	9.118177e-01	9.480599e-01	12	122861706	122861715	10	+	1.826	1.829	0.007
ENSG00000130787	E048	242.785787	0.0003152321	7.365053e-02	1.493756e-01	12	122861716	122861997	282	+	2.263	2.320	0.188
ENSG00000130787	E049	140.204276	0.0002451127	1.007310e-01	1.915752e-01	12	122861998	122862103	106	+	2.019	2.084	0.220
ENSG00000130787	E050	398.317514	0.0027808036	5.227506e-08	5.615101e-07	12	122862104	122862961	858	+	2.373	2.562	0.629

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000130787

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3