ENSG00000130147

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC

ENST00000392011	ENSG00000130147	HEK293_OSMI2_2hA	HEK293_TMG_2hB	SH3BP4	protein_coding	protein_coding	7.532821	8.66237	6.736982	0.5574667	0.1620477	-0.362184	6.8567216	7.1703361	6.4537093	1.00108405	0.10194885	-0.151689	0.91434167	0.82106667	0.95836667	0.13730000	0.067780473	0.000606006	FALSE
ENST00000484097	ENSG00000130147	HEK293_OSMI2_2hA	HEK293_TMG_2hB	SH3BP4	protein_coding	processed_transcript	7.532821	8.66237	6.736982	0.5574667	0.1620477	-0.362184	0.3039479	0.6462394	0.1210871	0.07883963	0.03083864	-2.323696	0.03689583	0.07433333	0.01780000	-0.05653333	0.000606006	0.000606006
MSTRG.20103.3	ENSG00000130147	HEK293_OSMI2_2hA	HEK293_TMG_2hB	SH3BP4	protein_coding		7.532821	8.66237	6.736982	0.5574667	0.1620477	-0.362184	0.2213416	0.7045166	0.1183402	0.57909577	0.03775950	-2.476994	0.02960000	0.08716667	0.01766667	-0.06950000	0.897779182	0.000606006	FALSE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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HEK293_TMG_2hB
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log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000130147	E001	2.6583348	0.005886613	6.527736e-03	1.999450e-02	2	234952017	234952034	18	+	0.736	0.350	-1.844
ENSG00000130147	E002	3.0270290	0.005149538	8.791215e-03	2.576212e-02	2	234952035	234952041	7	+	0.763	0.406	-1.628
ENSG00000130147	E003	5.5242965	0.003188180	1.040956e-03	4.100683e-03	2	234952042	234952075	34	+	0.980	0.612	-1.465
ENSG00000130147	E004	15.7314535	0.025141638	6.104932e-02	1.284012e-01	2	234952076	234952170	95	+	1.289	1.150	-0.490
ENSG00000130147	E005	4.8146943	0.003613326	1.492426e-03	5.611617e-03	2	234952715	234953190	476	+	0.374	0.910	2.381
ENSG00000130147	E006	0.0000000				2	234978685	234978699	15	+
ENSG00000130147	E007	0.0000000				2	234978700	234978702	3	+
ENSG00000130147	E008	0.0000000				2	234978703	234978704	2	+
ENSG00000130147	E009	0.0000000				2	234978705	234978900	196	+
ENSG00000130147	E010	0.0000000				2	234978901	234978985	85	+
ENSG00000130147	E011	0.6643356	0.867411198	4.214046e-01	5.645598e-01	2	234979462	234979898	437	+	0.000	0.308	10.184
ENSG00000130147	E012	0.0000000				2	234981624	234981633	10	+
ENSG00000130147	E013	0.0000000				2	234981634	234981727	94	+
ENSG00000130147	E014	0.0000000				2	234983243	234983296	54	+
ENSG00000130147	E015	0.0000000				2	234994524	234994628	105	+
ENSG00000130147	E016	0.0000000				2	234994840	234994960	121	+
ENSG00000130147	E017	18.9141256	0.017792287	3.232316e-03	1.095090e-02	2	234995303	234995376	74	+	1.403	1.179	-0.785
ENSG00000130147	E018	0.2955422	0.028873598	8.501022e-01		2	234995692	234995993	302	+	0.128	0.117	-0.146
ENSG00000130147	E019	0.0000000				2	235008560	235008594	35	+
ENSG00000130147	E020	26.9514007	0.004569445	1.866158e-03	6.809304e-03	2	235034871	235034954	84	+	1.520	1.363	-0.544
ENSG00000130147	E021	45.6678819	0.003121606	1.915559e-03	6.963920e-03	2	235034955	235035120	166	+	1.719	1.610	-0.368
ENSG00000130147	E022	58.6635772	0.003153855	7.456639e-05	4.021058e-04	2	235040888	235041037	150	+	1.839	1.702	-0.463
ENSG00000130147	E023	86.8508116	0.002092571	1.309401e-08	1.579711e-07	2	235041038	235041361	324	+	2.024	1.854	-0.570
ENSG00000130147	E024	356.7311387	0.001045107	5.853023e-03	1.822577e-02	2	235041362	235043247	1886	+	2.540	2.556	0.053
ENSG00000130147	E025	82.2943998	0.002133807	9.970481e-01	1.000000e+00	2	235052562	235052750	189	+	1.878	1.947	0.231
ENSG00000130147	E026	528.3013351	0.006621673	4.070442e-09	5.389147e-08	2	235053592	235055714	2123	+	2.576	2.803	0.754

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000130147

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3