ENSG00000129347

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000312962	ENSG00000129347	HEK293_OSMI2_2hA	HEK293_TMG_2hB	KRI1	protein_coding	protein_coding	58.36641	69.94511	49.23472	2.007586	1.359482	-0.5064604	34.809351	56.302670	20.720239	0.8995656	1.962282	-1.441723	0.5692500	0.8057000	0.4228333	-0.3828667	3.159997e-09	8.540077e-27	FALSE	TRUE
ENST00000478863	ENSG00000129347	HEK293_OSMI2_2hA	HEK293_TMG_2hB	KRI1	protein_coding	retained_intron	58.36641	69.94511	49.23472	2.007586	1.359482	-0.5064604	11.501747	8.942834	12.545273	0.6980725	1.242681	0.487877	0.2077125	0.1275333	0.2541000	0.1265667	1.317579e-05	8.540077e-27	TRUE	TRUE
MSTRG.16417.9	ENSG00000129347	HEK293_OSMI2_2hA	HEK293_TMG_2hB	KRI1	protein_coding		58.36641	69.94511	49.23472	2.007586	1.359482	-0.5064604	3.187176	0.000000	5.884544	0.0000000	1.157276	9.203236	0.0600750	0.0000000	0.1186000	0.1186000	8.540077e-27	8.540077e-27	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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dispersion
pvalue
padj
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HEK293_TMG_2hB
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log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000129347	E001	2.4239094	0.0305810434	2.329710e-01	3.659581e-01	19	10553085	10553090	6	-	0.364	0.588	1.129
ENSG00000129347	E002	111.3864604	0.0004829386	4.564030e-10	7.198272e-09	19	10553091	10553212	122	-	1.833	2.084	0.845
ENSG00000129347	E003	420.0487447	0.0031319248	6.058449e-06	4.232915e-05	19	10553213	10553575	363	-	2.478	2.636	0.527
ENSG00000129347	E004	79.6160113	0.0078792934	8.347168e-05	4.444230e-04	19	10553576	10553590	15	-	1.684	1.940	0.865
ENSG00000129347	E005	98.8747074	0.0060633719	3.674563e-04	1.648231e-03	19	10553591	10553607	17	-	1.819	2.024	0.692
ENSG00000129347	E006	1227.5005560	0.0011657060	2.453922e-10	4.046729e-09	19	10553608	10554281	674	-	2.966	3.093	0.420
ENSG00000129347	E007	341.0246106	0.0001437069	4.696064e-05	2.664037e-04	19	10555087	10555130	44	-	2.434	2.526	0.307
ENSG00000129347	E008	383.3008257	0.0001382383	5.851135e-03	1.822139e-02	19	10555131	10555185	55	-	2.507	2.568	0.202
ENSG00000129347	E009	312.6808264	0.0002280200	1.628454e-01	2.788525e-01	19	10555285	10555308	24	-	2.435	2.472	0.123
ENSG00000129347	E010	327.1660273	0.0001723672	3.899383e-01	5.339779e-01	19	10555309	10555349	41	-	2.465	2.489	0.081
ENSG00000129347	E011	238.4143730	0.0003704979	7.739726e-01	8.542445e-01	19	10557552	10557557	6	-	2.338	2.351	0.045
ENSG00000129347	E012	519.1085791	0.0001504435	3.678283e-01	5.122111e-01	19	10557558	10557682	125	-	2.666	2.687	0.071
ENSG00000129347	E013	87.7666334	0.0039024310	3.538214e-03	1.183488e-02	19	10557683	10557768	86	-	2.001	1.864	-0.459
ENSG00000129347	E014	282.4970460	0.0001707871	3.144598e-02	7.477809e-02	19	10557769	10557790	22	-	2.378	2.434	0.185
ENSG00000129347	E015	423.1687693	0.0001819410	5.833339e-02	1.237718e-01	19	10557791	10557895	105	-	2.563	2.605	0.140
ENSG00000129347	E016	429.3099219	0.0001248131	2.641084e-01	4.020517e-01	19	10557972	10558060	89	-	2.581	2.607	0.088
ENSG00000129347	E017	14.6626556	0.0047299022	1.613620e-04	7.978061e-04	19	10558061	10558163	103	-	1.360	1.019	-1.216
ENSG00000129347	E018	443.2494136	0.0003658892	8.830107e-01	9.291278e-01	19	10558164	10558239	76	-	2.608	2.617	0.031
ENSG00000129347	E019	642.8300936	0.0001186080	7.660060e-01	8.486213e-01	19	10559359	10559529	171	-	2.774	2.776	0.005
ENSG00000129347	E020	14.1499787	0.0773703444	1.288773e-03	4.938891e-03	19	10559530	10559612	83	-	1.430	0.916	-1.840
ENSG00000129347	E021	450.0809593	0.0001328778	6.139230e-01	7.325176e-01	19	10559613	10559708	96	-	2.623	2.620	-0.011
ENSG00000129347	E022	2.2386347	0.5243511930	9.695523e-01	9.849626e-01	19	10559709	10559807	99	-	0.614	0.421	-0.926
ENSG00000129347	E023	1.2951885	0.0102233104	3.979138e-01	5.416576e-01	19	10559808	10559809	2	-	0.440	0.294	-0.860
ENSG00000129347	E024	430.1917117	0.0002784761	1.032986e-01	1.954967e-01	19	10559810	10559936	127	-	2.616	2.591	-0.086
ENSG00000129347	E025	21.3147907	0.0140323723	1.583632e-02	4.237192e-02	19	10560276	10560311	36	-	1.457	1.239	-0.757
ENSG00000129347	E026	346.5510441	0.0010305391	2.940192e-03	1.008803e-02	19	10560312	10560371	60	-	2.552	2.484	-0.226
ENSG00000129347	E027	234.2740483	0.0015550327	1.875824e-03	6.840996e-03	19	10560372	10560380	9	-	2.396	2.308	-0.295
ENSG00000129347	E028	389.5339506	0.0001735664	2.395842e-04	1.131572e-03	19	10560381	10560448	68	-	2.602	2.536	-0.217
ENSG00000129347	E029	415.1664504	0.0010714977	5.860909e-04	2.482242e-03	19	10561003	10561080	78	-	2.637	2.562	-0.250
ENSG00000129347	E030	365.2216726	0.0009777301	1.375572e-01	2.446838e-01	19	10561169	10561232	64	-	2.552	2.521	-0.100
ENSG00000129347	E031	333.2911320	0.0001515150	1.530131e-01	2.657706e-01	19	10561233	10561265	33	-	2.507	2.483	-0.080
ENSG00000129347	E032	361.9064119	0.0001463914	7.082120e-04	2.928615e-03	19	10561667	10561716	50	-	2.568	2.507	-0.204
ENSG00000129347	E033	2.7106593	0.0095789155	1.604953e-02	4.284557e-02	19	10561717	10561790	74	-	0.765	0.389	-1.735
ENSG00000129347	E034	358.6818725	0.0001568867	2.653924e-05	1.598963e-04	19	10561791	10561845	55	-	2.574	2.497	-0.259
ENSG00000129347	E035	432.4639291	0.0005451562	3.566495e-04	1.605902e-03	19	10562729	10562821	93	-	2.647	2.579	-0.226
ENSG00000129347	E036	206.4904071	0.0002041628	2.667044e-03	9.273749e-03	19	10562822	10562825	4	-	2.331	2.258	-0.243
ENSG00000129347	E037	217.7717692	0.0011729995	1.356025e-02	3.721496e-02	19	10562826	10562837	12	-	2.350	2.283	-0.225
ENSG00000129347	E038	361.2187112	0.0025669472	6.882078e-02	1.414180e-01	19	10564929	10565034	106	-	2.559	2.508	-0.169
ENSG00000129347	E039	32.8687366	0.0059909639	1.391967e-19	8.473781e-18	19	10565035	10565716	682	-	1.825	1.184	-2.206
ENSG00000129347	E040	257.0942219	0.0011314034	1.870497e-01	3.100291e-01	19	10565717	10565790	74	-	2.397	2.366	-0.105
ENSG00000129347	E041	0.8157519	0.0158437925	2.664467e-01	4.046296e-01	19	10565791	10565905	115	-	0.365	0.171	-1.445
ENSG00000129347	E042	203.5598510	0.0042611797	7.288520e-01	8.212183e-01	19	10565906	10566031	126	-	2.279	2.273	-0.023

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000129347

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3