ENSG00000125247

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-8 / 8
Columns:
Select all:
isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
Close
Columns▼Records:
Use the filters above each column to filter and limit table data. Advanced searches can be performed by using the following operators:
<, <=, >, >=, =, *, !, {, }, ||,&&, **[empty]**, **[nonempty]**, **rgx:**
Learn more
TableFilter v0.7.3
https://www.tablefilter.com/
©2015-2025 Max Guglielmi
Close
?
Page of 1
isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000342624	ENSG00000125247	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TMTC4	protein_coding	protein_coding	7.709052	6.735621	8.864212	0.07348854	0.2193565	0.3956679	0.9325311	0.89999663	1.4892600	0.37188767	0.7239514	0.7203175	0.1140917	0.13376667	0.17143333	0.03766667	9.278542e-01	1.584942e-07	FALSE	TRUE
ENST00000376234	ENSG00000125247	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TMTC4	protein_coding	protein_coding	7.709052	6.735621	8.864212	0.07348854	0.2193565	0.3956679	2.9567725	2.46991807	3.5928521	0.37740219	0.4146809	0.5388470	0.3773083	0.36566667	0.40396667	0.03830000	8.488863e-01	1.584942e-07	FALSE	TRUE
ENST00000462211	ENSG00000125247	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TMTC4	protein_coding	processed_transcript	7.709052	6.735621	8.864212	0.07348854	0.2193565	0.3956679	0.7947033	1.26438091	0.3659350	0.17595531	0.3659350	-1.7612415	0.1133417	0.18800000	0.03936667	-0.14863333	1.112171e-01	1.584942e-07	FALSE	TRUE
ENST00000475272	ENSG00000125247	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TMTC4	protein_coding	protein_coding	7.709052	6.735621	8.864212	0.07348854	0.2193565	0.3956679	0.4301991	0.35871173	0.0000000	0.35871173	0.0000000	-5.2044214	0.0527000	0.05433333	0.00000000	-0.05433333	7.710891e-01	1.584942e-07		FALSE
ENST00000489713	ENSG00000125247	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TMTC4	protein_coding	retained_intron	7.709052	6.735621	8.864212	0.07348854	0.2193565	0.3956679	0.3639612	0.35839245	0.3161379	0.08520085	0.0301593	-0.1757615	0.0502000	0.05293333	0.03586667	-0.01706667	5.498204e-01	1.584942e-07	FALSE	TRUE
MSTRG.9036.4	ENSG00000125247	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TMTC4	protein_coding		7.709052	6.735621	8.864212	0.07348854	0.2193565	0.3956679	0.2187418	0.00000000	1.1147410	0.00000000	0.2799096	6.8134490	0.0259625	0.00000000	0.12743333	0.12743333	1.584942e-07	1.584942e-07	FALSE	TRUE
MSTRG.9036.5	ENSG00000125247	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TMTC4	protein_coding		7.709052	6.735621	8.864212	0.07348854	0.2193565	0.3956679	0.7716255	0.08683983	0.8244235	0.05305205	0.4754213	3.1071073	0.0854125	0.01273333	0.09253333	0.07980000	6.387497e-01	1.584942e-07	FALSE	TRUE
MSTRG.9036.7	ENSG00000125247	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TMTC4	protein_coding		7.709052	6.735621	8.864212	0.07348854	0.2193565	0.3956679	0.7930974	1.04713456	0.4395341	0.44801370	0.4395341	-1.2336564	0.1250042	0.15520000	0.04730000	-0.10790000	2.029400e-01	1.584942e-07	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 42
Columns:
Select all:
groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
Close
Columns▼Records:
Use the filters above each column to filter and limit table data. Advanced searches can be performed by using the following operators:
<, <=, >, >=, =, *, !, {, }, ||,&&, **[empty]**, **[nonempty]**, **rgx:**
Learn more
TableFilter v0.7.3
https://www.tablefilter.com/
©2015-2025 Max Guglielmi
Close
?
Page of 5
groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000125247	E001	4.3908986	0.0123842545	2.544843e-01	3.911793e-01	13	100603625	100603926	302	-	0.646	0.816	0.694
ENSG00000125247	E002	68.1120229	0.0137121559	8.124866e-02	1.615042e-01	13	100603927	100604298	372	-	1.775	1.909	0.451
ENSG00000125247	E003	17.2951729	0.0012823556	1.645617e-02	4.374067e-02	13	100604299	100604300	2	-	1.159	1.359	0.702
ENSG00000125247	E004	37.7668951	0.0007786302	2.982432e-02	7.161832e-02	13	100604301	100604390	90	-	1.530	1.657	0.434
ENSG00000125247	E005	51.9892615	0.0036005344	3.059977e-02	7.314500e-02	13	100604391	100604705	315	-	1.664	1.791	0.429
ENSG00000125247	E006	27.0511038	0.0151525159	7.766023e-01	8.561244e-01	13	100604706	100604870	165	-	1.432	1.464	0.111
ENSG00000125247	E007	38.2193639	0.0097548393	4.216344e-03	1.374778e-02	13	100604871	100605040	170	-	1.683	1.479	-0.695
ENSG00000125247	E008	41.1930001	0.0330490960	8.522470e-02	1.677757e-01	13	100605041	100605142	102	-	1.700	1.540	-0.546
ENSG00000125247	E009	31.6823690	0.0008203947	1.594834e-02	4.261567e-02	13	100606358	100606427	70	-	1.585	1.442	-0.490
ENSG00000125247	E010	41.6484312	0.0008196523	1.592616e-03	5.936026e-03	13	100612398	100612510	113	-	1.708	1.540	-0.570
ENSG00000125247	E011	38.7434514	0.0005986226	8.968183e-06	6.028654e-05	13	100614316	100614430	115	-	1.703	1.454	-0.851
ENSG00000125247	E012	5.0035872	0.1049830548	9.429124e-03	2.735348e-02	13	100624797	100624909	113	-	0.477	0.973	2.068
ENSG00000125247	E013	5.8463072	0.0365643947	4.664701e-03	1.499701e-02	13	100624910	100624968	59	-	0.586	1.021	1.734
ENSG00000125247	E014	13.0887224	0.0090529421	6.547793e-03	2.004881e-02	13	100624969	100625452	484	-	1.006	1.287	1.006
ENSG00000125247	E015	8.2101400	0.0024735629	3.808655e-04	1.700738e-03	13	100625453	100625534	82	-	0.723	1.133	1.554
ENSG00000125247	E016	61.4673423	0.0004625388	6.551099e-01	7.650683e-01	13	100625535	100625676	142	-	1.805	1.791	-0.050
ENSG00000125247	E017	51.1846082	0.0058309578	7.327028e-02	1.487477e-01	13	100625785	100625892	108	-	1.662	1.769	0.364
ENSG00000125247	E018	50.2721575	0.0037801494	5.435525e-02	1.168689e-01	13	100626071	100626150	80	-	1.653	1.761	0.366
ENSG00000125247	E019	61.9067516	0.0174577346	3.069933e-01	4.491664e-01	13	100634805	100634936	132	-	1.763	1.835	0.243
ENSG00000125247	E020	0.8232405	0.1637664061	3.450888e-01	4.891732e-01	13	100634937	100635023	87	-	0.332	0.138	-1.613
ENSG00000125247	E021	39.2930509	0.0072272324	7.050084e-01	8.034464e-01	13	100635024	100635064	41	-	1.595	1.620	0.086
ENSG00000125247	E022	55.0567767	0.0004434994	6.118907e-01	7.309329e-01	13	100635065	100635195	131	-	1.763	1.744	-0.063
ENSG00000125247	E023	0.2214452	0.0411681124	3.796420e-01		13	100635679	100635779	101	-	0.000	0.137	10.973
ENSG00000125247	E024	59.9342354	0.0005546548	5.472370e-01	6.773185e-01	13	100636532	100636734	203	-	1.799	1.777	-0.075
ENSG00000125247	E025	51.3037876	0.0056396040	3.285840e-01	4.720895e-01	13	100637538	100637702	165	-	1.745	1.696	-0.167
ENSG00000125247	E026	1.1081710	0.1078370221	6.891436e-02	1.415734e-01	13	100637703	100637929	227	-	0.109	0.458	2.710
ENSG00000125247	E027	49.6979069	0.0043449751	1.154025e-01	2.134296e-01	13	100637930	100638022	93	-	1.747	1.663	-0.285
ENSG00000125247	E028	5.0229897	0.0031704133	2.070873e-02	5.297407e-02	13	100638023	100638808	786	-	0.911	0.598	-1.270
ENSG00000125247	E029	44.0171449	0.0008121442	1.780415e-02	4.671538e-02	13	100642211	100642311	101	-	1.713	1.592	-0.408
ENSG00000125247	E030	36.0456375	0.0005920827	6.352517e-01	7.495938e-01	13	100656381	100656468	88	-	1.585	1.563	-0.075
ENSG00000125247	E031	57.4497558	0.0026299767	7.053275e-01	8.037250e-01	13	100662964	100663119	156	-	1.775	1.758	-0.058
ENSG00000125247	E032	43.2140381	0.0018661415	6.217554e-01	7.386926e-01	13	100663120	100663180	61	-	1.631	1.661	0.103
ENSG00000125247	E033	50.8330712	0.0058937765	2.779825e-01	4.176194e-01	13	100664221	100664336	116	-	1.683	1.747	0.216
ENSG00000125247	E034	0.1451727	0.0432116451	6.258496e-01		13	100665969	100666107	139	-	0.109	0.000	-10.494
ENSG00000125247	E035	0.4782907	0.0217681645	5.300321e-02	1.144908e-01	13	100668362	100668578	217	-	0.000	0.324	12.551
ENSG00000125247	E036	66.9323950	0.0024614482	6.596979e-01	7.684727e-01	13	100668579	100668794	216	-	1.822	1.844	0.074
ENSG00000125247	E037	0.9943357	0.0132917849	6.081413e-01	7.279839e-01	13	100670283	100670359	77	-	0.331	0.241	-0.624
ENSG00000125247	E038	36.9482715	0.0186521415	5.825287e-01	7.068770e-01	13	100670360	100670569	210	-	1.603	1.548	-0.190
ENSG00000125247	E039	1.1823829	0.0873914604	9.954298e-01	1.000000e+00	13	100670570	100670735	166	-	0.331	0.326	-0.030
ENSG00000125247	E040	0.5911862	0.0184777668	6.563762e-02	1.361038e-01	13	100672691	100672791	101	-	0.331	0.000	-12.495
ENSG00000125247	E041	16.9134254	0.0424826577	6.428882e-01	7.555629e-01	13	100674744	100674879	136	-	1.285	1.225	-0.209
ENSG00000125247	E042	1.3713618	0.0446485846	9.953023e-01	1.000000e+00	13	100674940	100675093	154	-	0.386	0.393	0.042

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000125247

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3