• ENSG00000121350
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000121350

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000240651 ENSG00000121350 HEK293_OSMI2_2hA HEK293_TMG_2hB PYROXD1 protein_coding protein_coding 2.640607 0.5788488 4.889065 0.1364457 0.09365235 3.056537 1.84405450 0.35082062 3.26796883 0.03023729 0.05010648 3.183448 0.72763333 0.6470 0.66890000 0.02190000 0.8197443227 0.0008253443 FALSE TRUE
ENST00000538072 ENSG00000121350 HEK293_OSMI2_2hA HEK293_TMG_2hB PYROXD1 protein_coding retained_intron 2.640607 0.5788488 4.889065 0.1364457 0.09365235 3.056537 0.12092449 0.00000000 0.28147819 0.00000000 0.15111236 4.865316 0.02415417 0.0000 0.05716667 0.05716667 0.6712223398 0.0008253443   FALSE
ENST00000538615 ENSG00000121350 HEK293_OSMI2_2hA HEK293_TMG_2hB PYROXD1 protein_coding retained_intron 2.640607 0.5788488 4.889065 0.1364457 0.09365235 3.056537 0.03514075 0.03926406 0.01311208 0.03926406 0.01311208 -1.091888 0.03583333 0.0953 0.00270000 -0.09260000 0.3785389145 0.0008253443 FALSE TRUE
ENST00000543476 ENSG00000121350 HEK293_OSMI2_2hA HEK293_TMG_2hB PYROXD1 protein_coding nonsense_mediated_decay 2.640607 0.5788488 4.889065 0.1364457 0.09365235 3.056537 0.48166255 0.00000000 0.94200952 0.00000000 0.11886516 6.572904 0.11089583 0.0000 0.19193333 0.19193333 0.0008253443 0.0008253443 TRUE TRUE
ENST00000544187 ENSG00000121350 HEK293_OSMI2_2hA HEK293_TMG_2hB PYROXD1 protein_coding nonsense_mediated_decay 2.640607 0.5788488 4.889065 0.1364457 0.09365235 3.056537 0.07853319 0.18876407 0.13041305 0.13553459 0.07595059 -0.501380 0.05477083 0.2577 0.02686667 -0.23083333 0.2847215361 0.0008253443   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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Columns▼Records:
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<, <=, >, >=, =, *, !, {, }, ||,&&, [empty], [nonempty], rgx:
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©2015-2025 Max Guglielmi
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groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_2hBColumn filter
HEK293_OSMI2_2hAColumn filter
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hBColumn filter
ENSG00000121350 E001 0.1472490 0.0446219280 0.606033577   12 21437615 21437644 30 + 0.044 0.000 -7.164
ENSG00000121350 E002 0.1472490 0.0446219280 0.606033577   12 21437645 21437654 10 + 0.044 0.000 -8.850
ENSG00000121350 E003 3.2193320 0.0047855492 0.489142928 0.62663390 12 21437655 21437704 50 + 0.464 0.601 0.647
ENSG00000121350 E004 8.9434983 0.0019418624 0.772941298 0.85346418 12 21437705 21437814 110 + 0.828 0.777 -0.201
ENSG00000121350 E005 0.5891098 0.0183779393 1.000000000 1.00000000 12 21437915 21438538 624 + 0.154 0.000 -10.721
ENSG00000121350 E006 10.7118574 0.0017075661 0.897943593 0.93885855 12 21440368 21440448 81 + 0.886 0.902 0.063
ENSG00000121350 E007 0.4482035 0.0257185653 1.000000000 1.00000000 12 21441207 21441300 94 + 0.120 0.000 -10.348
ENSG00000121350 E008 18.2617810 0.0011240354 0.417353053 0.56072156 12 21445347 21445466 120 + 1.107 0.999 -0.392
ENSG00000121350 E009 23.6271081 0.0034525686 0.260626337 0.39818450 12 21449563 21449691 129 + 1.215 1.079 -0.488
ENSG00000121350 E010 18.5845425 0.0009957512 0.471319246 0.61044655 12 21452081 21452154 74 + 1.096 1.175 0.285
ENSG00000121350 E011 1.1781059 0.0979272176 0.507503758 0.64299467 12 21454782 21455131 350 + 0.267 0.000 -11.363
ENSG00000121350 E012 24.5090535 0.0027772276 0.478976417 0.61739250 12 21455132 21455241 110 + 1.228 1.145 -0.296
ENSG00000121350 E013 18.4888419 0.0181112702 0.147660840 0.25851257 12 21455242 21455292 51 + 1.127 0.902 -0.829
ENSG00000121350 E014 22.5508936 0.0084445129 0.528151465 0.66105994 12 21455995 21456095 101 + 1.194 1.113 -0.289
ENSG00000121350 E015 1.5930080 0.0116606367 0.006764821 0.02061139 12 21456865 21457086 222 + 0.185 0.699 2.914
ENSG00000121350 E016 0.2987644 0.0278684590 1.000000000   12 21460903 21461024 122 + 0.084 0.000 -9.827
ENSG00000121350 E017 20.3363442 0.0009490017 0.953068703 0.97462974 12 21461025 21461154 130 + 1.141 1.145 0.014
ENSG00000121350 E018 20.6092893 0.0009464809 0.199110454 0.32510992 12 21462008 21462120 113 + 1.164 0.999 -0.598
ENSG00000121350 E019 0.1515154 0.0431196781 0.605055741   12 21462121 21462125 5 + 0.044 0.000 -8.855
ENSG00000121350 E020 16.7800054 0.0012446339 0.587211804 0.71054339 12 21462740 21462862 123 + 1.073 0.999 -0.271
ENSG00000121350 E021 0.4407149 0.0219117416 0.219487765 0.34977539 12 21467290 21467480 191 + 0.084 0.300 2.230
ENSG00000121350 E022 12.8846924 0.0014866218 0.962605318 0.98039186 12 21467481 21467618 138 + 0.963 0.953 -0.035
ENSG00000121350 E023 88.8743390 0.0010112702 0.008143827 0.02414775 12 21468506 21471250 2745 + 1.746 1.868 0.412