ENSG00000119403

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000312189 ENSG00000119403 HEK293_OSMI2_2hA HEK293_TMG_2hB PHF19 protein_coding protein_coding 48.7334 100.532 26.39347 4.135291 0.3136286 -1.928998 41.955765 91.218130 21.899668 3.0882262 0.2819672 -2.057911 0.8271542 0.90790000 0.8297333 -0.07816667 1.349484e-05 9.412013e-09 FALSE  
ENST00000373896 ENSG00000119403 HEK293_OSMI2_2hA HEK293_TMG_2hB PHF19 protein_coding protein_coding 48.7334 100.532 26.39347 4.135291 0.3136286 -1.928998 4.696765 7.022808 2.949437 0.4962077 0.3213264 -1.248778 0.1124583 0.06976667 0.1115000 0.04173333 2.029307e-02 9.412013e-09 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000119403 E001 0.0000000       9 120855651 120855651 1 -      
ENSG00000119403 E002 0.9211812 0.0138593753 2.935173e-01 4.345914e-01 9 120855652 120855697 46 - 0.000 0.263 9.747
ENSG00000119403 E003 413.5475261 0.0001989498 1.756778e-15 6.433718e-14 9 120855698 120857929 2232 - 2.610 2.468 -0.474
ENSG00000119403 E004 68.7819476 0.0006702744 8.489037e-04 3.433878e-03 9 120857930 120858193 264 - 1.844 1.695 -0.505
ENSG00000119403 E005 41.6803581 0.0090896306 3.243135e-02 7.668717e-02 9 120858194 120858286 93 - 1.628 1.483 -0.496
ENSG00000119403 E006 40.0704327 0.0032433801 3.750807e-02 8.642096e-02 9 120860090 120860185 96 - 1.594 1.468 -0.433
ENSG00000119403 E007 1.7168989 0.1365292219 9.879414e-01 9.965048e-01 9 120860186 120860546 361 - 0.357 0.367 0.063
ENSG00000119403 E008 1.1707547 0.3007606862 2.089312e-01 3.372433e-01 9 120860912 120861088 177 - 0.464 0.223 -1.512
ENSG00000119403 E009 22.6878997 0.0207442430 2.359604e-01 3.694899e-01 9 120861089 120861110 22 - 1.343 1.235 -0.379
ENSG00000119403 E010 31.7773175 0.0167304596 7.510610e-02 1.517008e-01 9 120861111 120861174 64 - 1.517 1.370 -0.508
ENSG00000119403 E011 24.1665186 0.0079668286 2.045176e-01 3.318111e-01 9 120861918 120861987 70 - 1.368 1.270 -0.341
ENSG00000119403 E012 16.3451216 0.0011824311 2.113416e-01 3.400727e-01 9 120861988 120862005 18 - 1.212 1.107 -0.376
ENSG00000119403 E013 22.8955460 0.0075165495 8.674939e-02 1.702060e-01 9 120862588 120862612 25 - 1.379 1.241 -0.484
ENSG00000119403 E014 38.0996025 0.0023935537 2.107720e-04 1.010038e-03 9 120862613 120862749 137 - 1.653 1.423 -0.789
ENSG00000119403 E015 6.5257114 0.0025501490 4.056097e-04 1.796329e-03 9 120862750 120863026 277 - 1.096 0.668 -1.652
ENSG00000119403 E016 21.1961572 0.0008780842 1.565924e-05 9.951346e-05 9 120864049 120864078 30 - 1.482 1.150 -1.160
ENSG00000119403 E017 22.3841111 0.0101424175 1.782617e-04 8.704350e-04 9 120864079 120864116 38 - 1.491 1.169 -1.123
ENSG00000119403 E018 26.6870461 0.0202937400 3.904180e-04 1.737660e-03 9 120865710 120865783 74 - 1.573 1.244 -1.138
ENSG00000119403 E019 18.7769067 0.0038053479 1.226734e-06 9.996606e-06 9 120865784 120865802 19 - 1.482 1.078 -1.418
ENSG00000119403 E020 19.4153198 0.0014299774 4.825345e-07 4.280116e-06 9 120865803 120865830 28 - 1.491 1.090 -1.407
ENSG00000119403 E021 3.1732288 0.0224529528 2.581269e-02 6.355509e-02 9 120865831 120866027 197 - 0.785 0.427 -1.609
ENSG00000119403 E022 25.2956804 0.0008046922 7.027220e-08 7.349485e-07 9 120866028 120866096 69 - 1.587 1.207 -1.315
ENSG00000119403 E023 24.4650239 0.0026155867 1.313817e-05 8.487880e-05 9 120866870 120866965 96 - 1.534 1.208 -1.131
ENSG00000119403 E024 1.3715628 0.0196241681 1.037655e-02 2.968793e-02 9 120868260 120868622 363 - 0.622 0.176 -2.674
ENSG00000119403 E025 2.8807341 0.2177423399 9.718714e-02 1.861791e-01 9 120868808 120869181 374 - 0.787 0.402 -1.749
ENSG00000119403 E026 21.2572976 0.0566170813 6.692160e-02 1.382540e-01 9 120869182 120869298 117 - 1.434 1.173 -0.911
ENSG00000119403 E027 11.3885761 0.0015636038 1.555930e-01 2.691954e-01 9 120869299 120869330 32 - 1.096 0.953 -0.525
ENSG00000119403 E028 489.8376016 0.0051624658 5.226586e-03 1.654736e-02 9 120869587 120869844 258 - 2.466 2.595 0.429
ENSG00000119403 E029 485.9853261 0.0030163500 1.875647e-04 9.104401e-04 9 120869845 120869945 101 - 2.450 2.593 0.477
ENSG00000119403 E030 408.2109955 0.0011442754 3.700443e-06 2.714991e-05 9 120870443 120870486 44 - 2.368 2.517 0.499
ENSG00000119403 E031 440.4728960 0.0018008828 1.488442e-05 9.508074e-05 9 120870487 120870538 52 - 2.400 2.549 0.499
ENSG00000119403 E032 435.1105080 0.0001539369 1.520475e-03 5.702934e-03 9 120873979 120874060 82 - 2.444 2.534 0.300
ENSG00000119403 E033 648.4911149 0.0007750258 5.126473e-01 6.475496e-01 9 120874556 120874756 201 - 2.663 2.698 0.116
ENSG00000119403 E034 1.1092152 0.0649078248 2.324245e-01 3.653269e-01 9 120875881 120876433 553 - 0.000 0.301 11.491
ENSG00000119403 E035 2.9777035 0.0446870577 9.071194e-01 9.450210e-01 9 120876981 120877090 110 - 0.464 0.504 0.196
ENSG00000119403 E036 256.9823711 0.0077603383 6.990105e-01 7.988457e-01 9 120877091 120877239 149 - 2.287 2.294 0.023
ENSG00000119403 E037 0.0000000       9 120894788 120894896 109 -