ENSG00000117155

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000342203 ENSG00000117155 HEK293_OSMI2_2hA HEK293_TMG_2hB SSX2IP protein_coding protein_coding 14.02797 2.903036 23.23585 0.2324715 1.262006 2.996378 3.8810827 1.50775937 6.637555 0.20039236 0.2667962 2.130881 0.34171667 0.52743333 0.28613333 -0.241300000 0.04601763 0.04601763 FALSE TRUE
ENST00000605755 ENSG00000117155 HEK293_OSMI2_2hA HEK293_TMG_2hB SSX2IP protein_coding protein_coding 14.02797 2.903036 23.23585 0.2324715 1.262006 2.996378 1.6882098 0.00000000 1.723563 0.00000000 1.0185023 7.437596 0.08673333 0.00000000 0.07113333 0.071133333 0.46681702 0.04601763 FALSE TRUE
MSTRG.1510.3 ENSG00000117155 HEK293_OSMI2_2hA HEK293_TMG_2hB SSX2IP protein_coding   14.02797 2.903036 23.23585 0.2324715 1.262006 2.996378 1.0148837 0.35457928 2.527527 0.35457928 0.6289271 2.799119 0.07013750 0.12880000 0.10640000 -0.022400000 0.51604321 0.04601763 FALSE TRUE
MSTRG.1510.5 ENSG00000117155 HEK293_OSMI2_2hA HEK293_TMG_2hB SSX2IP protein_coding   14.02797 2.903036 23.23585 0.2324715 1.262006 2.996378 3.7300675 0.32231026 6.903735 0.32231026 0.5564662 4.378863 0.19836667 0.09593333 0.29820000 0.202266667 0.17380427 0.04601763 FALSE TRUE
MSTRG.1510.7 ENSG00000117155 HEK293_OSMI2_2hA HEK293_TMG_2hB SSX2IP protein_coding   14.02797 2.903036 23.23585 0.2324715 1.262006 2.996378 0.9984199 0.02823101 1.185282 0.02823101 0.6137936 4.966464 0.07510833 0.01086667 0.05143333 0.040566667 0.74389546 0.04601763 FALSE TRUE
MSTRG.1510.9 ENSG00000117155 HEK293_OSMI2_2hA HEK293_TMG_2hB SSX2IP protein_coding   14.02797 2.903036 23.23585 0.2324715 1.262006 2.996378 1.8541842 0.38729471 3.045855 0.19389527 0.6502839 2.943294 0.14078333 0.13173333 0.13510000 0.003366667 0.92086592 0.04601763 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000117155 E001 0.0000000       1 84643706 84643706 1 -      
ENSG00000117155 E002 325.5847678 0.0160025450 1.671551e-04 8.229053e-04 1 84643707 84646845 3139 - 2.324 2.585 0.867
ENSG00000117155 E003 45.8645477 0.0005006312 3.496427e-03 1.171455e-02 1 84646846 84647022 177 - 1.490 1.713 0.760
ENSG00000117155 E004 18.2132351 0.0010509150 1.334472e-01 2.389276e-01 1 84647023 84647024 2 - 1.118 1.303 0.653
ENSG00000117155 E005 39.5697267 0.0010954176 1.516237e-02 4.085438e-02 1 84647025 84647062 38 - 1.430 1.637 0.707
ENSG00000117155 E006 68.5787378 0.0003930871 6.569017e-02 1.361964e-01 1 84647063 84647231 169 - 1.680 1.818 0.465
ENSG00000117155 E007 72.3430762 0.0003467404 1.996736e-01 3.258217e-01 1 84647232 84647338 107 - 1.711 1.817 0.359
ENSG00000117155 E008 34.2314224 0.0006215470 6.259100e-01 7.419528e-01 1 84647339 84647340 2 - 1.402 1.477 0.258
ENSG00000117155 E009 50.8842707 0.0004775570 3.764872e-01 5.208079e-01 1 84647341 84647375 35 - 1.567 1.661 0.319
ENSG00000117155 E010 139.9804535 0.0015903377 1.442713e-01 2.538180e-01 1 84647376 84647607 232 - 1.996 2.095 0.330
ENSG00000117155 E011 0.7427016 0.0153787590 5.031611e-01 6.391297e-01 1 84649630 84649670 41 - 0.214 0.000 -11.040
ENSG00000117155 E012 1.1135859 0.0113736998 1.000000e+00 1.000000e+00 1 84649671 84649948 278 - 0.247 0.262 0.115
ENSG00000117155 E013 2.3002246 0.0062819641 3.531009e-01 4.973487e-01 1 84649949 84650361 413 - 0.445 0.262 -1.108
ENSG00000117155 E014 52.1454779 0.0004637239 2.923792e-01 4.333466e-01 1 84650362 84650370 9 - 1.573 1.676 0.352
ENSG00000117155 E015 111.1722309 0.0003016629 3.402354e-02 7.980460e-02 1 84650371 84650527 157 - 1.891 2.020 0.431
ENSG00000117155 E016 74.2815594 0.0003193643 1.477048e-01 2.585705e-01 1 84651883 84651997 115 - 1.720 1.834 0.384
ENSG00000117155 E017 1.3318220 0.0234611079 1.125274e-01 2.092356e-01 1 84651998 84652441 444 - 0.215 0.543 1.965
ENSG00000117155 E018 0.5954526 0.0172671820 6.815864e-01 7.852282e-01 1 84655318 84655464 147 - 0.179 0.000 -10.718
ENSG00000117155 E019 0.7363589 0.0155673916 5.039817e-01 6.398992e-01 1 84655465 84655588 124 - 0.214 0.000 -11.040
ENSG00000117155 E020 107.3305161 0.0003146445 3.819314e-01 5.261893e-01 1 84655832 84656002 171 - 1.884 1.961 0.258
ENSG00000117155 E021 32.1085784 0.0006676055 2.943617e-01 4.354624e-01 1 84656003 84656005 3 - 1.391 1.337 -0.188
ENSG00000117155 E022 0.2924217 0.0272533373 1.000000e+00   1 84656006 84656013 8 - 0.099 0.000 -9.718
ENSG00000117155 E023 110.0469893 0.0002523633 1.256203e-01 2.280319e-01 1 84656348 84656484 137 - 1.913 1.879 -0.115
ENSG00000117155 E024 0.0000000       1 84658207 84658317 111 -      
ENSG00000117155 E025 124.1037935 0.0003069200 5.428148e-04 2.320224e-03 1 84658318 84658468 151 - 1.977 1.854 -0.413
ENSG00000117155 E026 73.9716061 0.0003786005 1.010967e-03 3.996424e-03 1 84662198 84662236 39 - 1.758 1.593 -0.561
ENSG00000117155 E027 94.8254277 0.0004959540 2.289104e-03 8.116942e-03 1 84662237 84662375 139 - 1.860 1.733 -0.427
ENSG00000117155 E028 1.2317032 0.1370514812 9.474256e-01 9.709449e-01 1 84662376 84662454 79 - 0.278 0.263 -0.111
ENSG00000117155 E029 68.6716678 0.0003837664 7.895601e-03 2.351625e-02 1 84662455 84662530 76 - 1.722 1.593 -0.439
ENSG00000117155 E030 95.7745154 0.0003225836 6.654994e-06 4.606389e-05 1 84664417 84664552 136 - 1.874 1.661 -0.720
ENSG00000117155 E031 0.1472490 0.0442819843 1.000000e+00   1 84666119 84666121 3 - 0.052 0.000 -8.719
ENSG00000117155 E032 101.3422596 0.0029221873 2.868106e-03 9.877370e-03 1 84666122 84666232 111 - 1.890 1.754 -0.458
ENSG00000117155 E033 116.7424673 0.0022179134 2.662535e-04 1.242142e-03 1 84669681 84669893 213 - 1.953 1.796 -0.530
ENSG00000117155 E034 1.8467225 0.0075380008 8.273310e-01 8.914380e-01 1 84669894 84670645 752 - 0.357 0.425 0.377
ENSG00000117155 E035 81.7085621 0.0003699277 1.359616e-02 3.729784e-02 1 84670646 84670815 170 - 1.794 1.691 -0.346
ENSG00000117155 E036 30.4006659 0.0006912348 2.442901e-03 8.591057e-03 1 84671177 84671188 12 - 1.394 1.128 -0.933
ENSG00000117155 E037 51.2373111 0.0004691796 5.853011e-05 3.241261e-04 1 84671189 84671308 120 - 1.615 1.337 -0.956
ENSG00000117155 E038 0.1451727 0.0426078051 1.000000e+00   1 84671309 84671315 7 - 0.052 0.000 -8.718
ENSG00000117155 E039 3.4185294 0.0062986453 4.120593e-01 5.556202e-01 1 84680338 84680387 50 - 0.566 0.425 -0.693
ENSG00000117155 E040 7.9999504 0.0021035975 1.262666e-01 2.289579e-01 1 84690154 84690370 217 - 0.861 0.635 -0.915
ENSG00000117155 E041 25.5115703 0.0007530231 3.012310e-03 1.030245e-02 1 84690371 84690533 163 - 1.326 1.039 -1.020
ENSG00000117155 E042 0.1515154 0.0431052397 1.000000e+00   1 84690674 84690803 130 - 0.052 0.000 -8.719