• ENSG00000115756
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000115756

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000307845 ENSG00000115756 HEK293_OSMI2_2hA HEK293_TMG_2hB HPCAL1 protein_coding protein_coding 22.58443 39.88515 13.73155 1.680075 0.6286033 -1.537669 8.3038226 10.7986100 7.0811033 2.35510778 0.22213572 -0.6080990 0.38093750 0.26726667 0.5169333 0.24966667 0.0059607658 0.0001505437 FALSE TRUE
ENST00000419810 ENSG00000115756 HEK293_OSMI2_2hA HEK293_TMG_2hB HPCAL1 protein_coding nonsense_mediated_decay 22.58443 39.88515 13.73155 1.680075 0.6286033 -1.537669 0.9105456 0.8330177 0.6626663 0.09658724 0.03237957 -0.3256720 0.05026250 0.02076667 0.0483000 0.02753333 0.0014405353 0.0001505437 TRUE TRUE
ENST00000622018 ENSG00000115756 HEK293_OSMI2_2hA HEK293_TMG_2hB HPCAL1 protein_coding protein_coding 22.58443 39.88515 13.73155 1.680075 0.6286033 -1.537669 10.8712619 25.2736900 3.8484388 1.21776694 0.69771826 -2.7121179 0.43974583 0.63756667 0.2777000 -0.35986667 0.0001505437 0.0001505437 FALSE TRUE
MSTRG.17946.2 ENSG00000115756 HEK293_OSMI2_2hA HEK293_TMG_2hB HPCAL1 protein_coding   22.58443 39.88515 13.73155 1.680075 0.6286033 -1.537669 1.2793608 1.7693514 1.4326665 0.16092690 0.36365042 -0.3026135 0.05970833 0.04476667 0.1061333 0.06136667 0.1615235738 0.0001505437 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_2hBColumn filter
HEK293_OSMI2_2hAColumn filter
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hBColumn filter
ENSG00000115756 E001 3.1949126 0.0053433263 4.772860e-02 1.051400e-01 2 10302889 10302893 5 + 0.764 0.475 -1.280
ENSG00000115756 E002 4.8440361 0.0196341905 2.978696e-04 1.370927e-03 2 10302894 10302896 3 + 1.026 0.529 -2.014
ENSG00000115756 E003 8.3964941 0.0021233686 5.130393e-05 2.882890e-04 2 10302897 10302903 7 + 1.189 0.760 -1.602
ENSG00000115756 E004 73.0073412 0.0161961574 8.870765e-05 4.689660e-04 2 10302904 10303177 274 + 1.974 1.721 -0.852
ENSG00000115756 E005 0.0000000       2 10303700 10303942 243 +      
ENSG00000115756 E006 0.0000000       2 10324347 10324396 50 +      
ENSG00000115756 E007 0.0000000       2 10330163 10330210 48 +      
ENSG00000115756 E008 0.0000000       2 10354216 10354381 166 +      
ENSG00000115756 E009 0.0000000       2 10368678 10368737 60 +      
ENSG00000115756 E010 0.0000000       2 10368764 10369217 454 +      
ENSG00000115756 E011 1.4403467 0.0164288661 4.815917e-01 6.197936e-01 2 10387761 10387810 50 + 0.416 0.299 -0.692
ENSG00000115756 E012 113.3464320 0.0029475758 1.347214e-02 3.701658e-02 2 10396835 10396920 86 + 2.044 1.963 -0.271
ENSG00000115756 E013 0.5212538 0.0203427839 7.638664e-01 8.470974e-01 2 10406265 10406361 97 + 0.186 0.145 -0.435
ENSG00000115756 E014 20.8420111 0.0061119928 2.122511e-02 5.406431e-02 2 10408562 10408734 173 + 1.399 1.226 -0.606
ENSG00000115756 E015 400.7409337 0.0005097588 5.050086e-02 1.100555e-01 2 10419734 10420020 287 + 2.538 2.525 -0.043
ENSG00000115756 E016 272.8626584 0.0002693185 1.084000e-01 2.031765e-01 2 10420021 10420135 115 + 2.311 2.376 0.218
ENSG00000115756 E017 247.5272623 0.0001970000 2.780463e-01 4.176714e-01 2 10422983 10423088 106 + 2.281 2.334 0.178
ENSG00000115756 E018 27.2224176 0.0139412375 3.029514e-06 2.264301e-05 2 10423089 10424524 1436 + 1.630 1.255 -1.294
ENSG00000115756 E019 9.2433784 0.0020326026 1.457749e-04 7.289782e-04 2 10424525 10424613 89 + 1.203 0.816 -1.432
ENSG00000115756 E020 44.9075277 0.0005206269 7.945526e-07 6.742469e-06 2 10424614 10425981 1368 + 1.761 1.515 -0.838
ENSG00000115756 E021 12.6515498 0.0017692996 4.799098e-02 1.056210e-01 2 10426220 10426495 276 + 1.189 1.013 -0.632
ENSG00000115756 E022 733.4331715 0.0035580135 2.783066e-08 3.153181e-07 2 10426724 10427692 969 + 2.667 2.826 0.529