ENSG00000114279

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000430714 ENSG00000114279 HEK293_OSMI2_2hA HEK293_TMG_2hB FGF12 protein_coding protein_coding 1.306318 1.358983 1.548227 0.2356917 0.3535038 0.1868009 0.08140423 0.00000000 0.0000000 0.00000000 0.000000000 0.0000000 0.05196250 0.00000000 0.0000000 0.00000000   0.04425849 FALSE TRUE
ENST00000440901 ENSG00000114279 HEK293_OSMI2_2hA HEK293_TMG_2hB FGF12 protein_coding processed_transcript 1.306318 1.358983 1.548227 0.2356917 0.3535038 0.1868009 0.49782845 0.87568047 0.3989140 0.23789561 0.208999249 -1.1149888 0.35220833 0.62426667 0.2220333 -0.40223333 0.18830969 0.04425849 FALSE TRUE
ENST00000445105 ENSG00000114279 HEK293_OSMI2_2hA HEK293_TMG_2hB FGF12 protein_coding protein_coding 1.306318 1.358983 1.548227 0.2356917 0.3535038 0.1868009 0.07162408 0.04053647 0.1413383 0.01015094 0.006676522 1.5823807 0.06399167 0.03220000 0.1003000 0.06810000 0.20617643 0.04425849 FALSE TRUE
ENST00000450716 ENSG00000114279 HEK293_OSMI2_2hA HEK293_TMG_2hB FGF12 protein_coding protein_coding 1.306318 1.358983 1.548227 0.2356917 0.3535038 0.1868009 0.28277505 0.09776470 0.6583718 0.09776470 0.123166961 2.6327662 0.19818333 0.06463333 0.4416667 0.37703333 0.04425849 0.04425849 FALSE TRUE
ENST00000454309 ENSG00000114279 HEK293_OSMI2_2hA HEK293_TMG_2hB FGF12 protein_coding protein_coding 1.306318 1.358983 1.548227 0.2356917 0.3535038 0.1868009 0.25548861 0.32951982 0.2913918 0.02619201 0.002874322 -0.1718558 0.24340417 0.26760000 0.2073333 -0.06026667 0.79794488 0.04425849 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000114279 E001 6.0442922 0.003061974 0.010286121 0.02947045 3 192139390 192141945 2556 - 1.003 0.679 -1.263
ENSG00000114279 E002 0.4355181 0.411759886 0.210897954 0.33960600 3 192141946 192141950 5 - 0.302 0.000 -13.763
ENSG00000114279 E003 0.4355181 0.411759886 0.210897954 0.33960600 3 192141951 192142048 98 - 0.302 0.000 -13.763
ENSG00000114279 E004 1.2105987 0.107720531 0.052005395 0.11273003 3 192142049 192142508 460 - 0.525 0.119 -2.896
ENSG00000114279 E005 4.5208607 0.013616343 0.119803470 0.21969864 3 192142509 192143598 1090 - 0.848 0.619 -0.939
ENSG00000114279 E006 14.2746875 0.001516763 0.035480445 0.08257836 3 192143599 192143977 379 - 1.082 1.248 0.591
ENSG00000114279 E007 6.0411614 0.006877919 0.076484204 0.15387241 3 192143978 192143987 10 - 0.702 0.917 0.849
ENSG00000114279 E008 10.9864499 0.001912133 0.045395623 0.10091959 3 192143988 192144059 72 - 0.973 1.153 0.655
ENSG00000114279 E009 12.9823219 0.002974722 0.194453026 0.31934103 3 192144060 192144127 68 - 1.094 1.198 0.371
ENSG00000114279 E010 10.6890084 0.001849942 0.370837478 0.51524794 3 192170458 192170563 106 - 1.017 1.092 0.271
ENSG00000114279 E011 7.5838351 0.003767129 0.723224906 0.81708922 3 192170564 192170656 93 - 0.906 0.933 0.102
ENSG00000114279 E012 0.0000000       3 192268651 192268749 99 -      
ENSG00000114279 E013 0.2924217 0.027724590 0.194710123   3 192308072 192310997 2926 - 0.223 0.000 -13.185
ENSG00000114279 E014 8.0789418 0.002410563 0.480626265 0.61887566 3 192335361 192335464 104 - 1.003 0.916 -0.324
ENSG00000114279 E015 8.2388022 0.002527755 0.480501213 0.61878115 3 192360428 192360538 111 - 1.017 0.932 -0.316
ENSG00000114279 E016 13.6581469 0.028711071 0.308820330 0.45109050 3 192408025 192409049 1025 - 1.106 1.200 0.338
ENSG00000114279 E017 0.0000000       3 192463295 192463392 98 -      
ENSG00000114279 E018 0.0000000       3 192672459 192673270 812 -      
ENSG00000114279 E019 0.0000000       3 192726882 192727180 299 -      
ENSG00000114279 E020 3.6621352 0.004712443 0.009607225 0.02779651 3 192727181 192727319 139 - 0.848 0.461 -1.678
ENSG00000114279 E021 1.2178718 0.010883670 0.138106526 0.24543924 3 192727320 192727323 4 - 0.479 0.212 -1.678
ENSG00000114279 E022 0.0000000       3 192727324 192727353 30 -      
ENSG00000114279 E023 0.0000000       3 192727354 192727483 130 -      
ENSG00000114279 E024 1.2178718 0.010883670 0.138106526 0.24543924 3 192727484 192727500 17 - 0.479 0.212 -1.678
ENSG00000114279 E025 1.2178718 0.010883670 0.138106526 0.24543924 3 192727501 192727525 25 - 0.479 0.212 -1.678
ENSG00000114279 E026 0.7675920 0.015328271 0.631913933 0.74686399 3 192727526 192727541 16 - 0.303 0.212 -0.678
ENSG00000114279 E027 0.4751703 0.021105766 0.586640580 0.71016971 3 192727542 192727559 18 - 0.126 0.212 0.906
ENSG00000114279 E028 0.1451727 0.042343106 0.480705272   3 192727560 192727566 7 - 0.126 0.000 -12.185
ENSG00000114279 E029 0.1451727 0.042343106 0.480705272   3 192727567 192727572 6 - 0.126 0.000 -12.185
ENSG00000114279 E030 0.1451727 0.042343106 0.480705272   3 192727573 192727587 15 - 0.126 0.000 -12.185
ENSG00000114279 E031 0.0000000       3 192767704 192767764 61 -