• ENSG00000113658
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000113658

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000507118 ENSG00000113658 HEK293_OSMI2_2hA HEK293_TMG_2hB SMAD5 protein_coding protein_coding 17.06989 3.228188 30.26055 0.5913918 0.7656017 3.224656 4.0300131 0.0000000 8.76867999 0.0000000 1.20796534 9.777860 0.1415167 0.00000000 0.288166667 0.2881667 1.898414e-15 1.898414e-15 FALSE FALSE
ENST00000514777 ENSG00000113658 HEK293_OSMI2_2hA HEK293_TMG_2hB SMAD5 protein_coding processed_transcript 17.06989 3.228188 30.26055 0.5913918 0.7656017 3.224656 0.3457186 0.8811144 0.04479981 0.4614183 0.04479981 -4.023368 0.1036667 0.24106667 0.001533333 -0.2395333 7.597496e-02 1.898414e-15 FALSE FALSE
ENST00000545279 ENSG00000113658 HEK293_OSMI2_2hA HEK293_TMG_2hB SMAD5 protein_coding protein_coding 17.06989 3.228188 30.26055 0.5913918 0.7656017 3.224656 5.3793989 0.1195460 10.78759571 0.1195460 0.72989139 6.381102 0.2591500 0.02743333 0.356866667 0.3294333 3.809885e-03 1.898414e-15 FALSE TRUE
ENST00000545620 ENSG00000113658 HEK293_OSMI2_2hA HEK293_TMG_2hB SMAD5 protein_coding protein_coding 17.06989 3.228188 30.26055 0.5913918 0.7656017 3.224656 5.9903062 1.8736901 8.20839877 0.2327211 1.34410053 2.125296 0.3921750 0.64000000 0.272200000 -0.3678000 3.613193e-01 1.898414e-15 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_2hBColumn filter
HEK293_OSMI2_2hAColumn filter
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hBColumn filter
ENSG00000113658 E001 0.4375944 0.0269478760 1.000000e+00 1.000000e+00 5 136132845 136132846 2 + 0.122 0.000 -12.512
ENSG00000113658 E002 0.4375944 0.0269478760 1.000000e+00 1.000000e+00 5 136132847 136132850 4 + 0.122 0.000 -13.723
ENSG00000113658 E003 8.3414770 0.0020039468 1.732820e-01 2.924703e-01 5 136132851 136132903 53 + 0.822 0.691 -0.530
ENSG00000113658 E004 14.4740783 0.0013156753 8.395355e-02 1.657331e-01 5 136132904 136132913 10 + 1.027 0.894 -0.498
ENSG00000113658 E005 41.5318380 0.0015249893 5.139225e-05 2.887082e-04 5 136132914 136132962 49 + 1.470 1.194 -0.962
ENSG00000113658 E006 0.8793415 0.1856887460 5.617934e-01 6.895193e-01 5 136132963 136133223 261 + 0.217 0.000 -14.273
ENSG00000113658 E007 1.3285892 0.0098197058 9.174964e-01 9.518842e-01 5 136133224 136133352 129 + 0.271 0.296 0.169
ENSG00000113658 E008 1.4864473 0.0087398118 8.047454e-01 8.757649e-01 5 136133353 136133473 121 + 0.296 0.296 -0.001
ENSG00000113658 E009 1.4938342 0.0779663413 5.677674e-01 6.945298e-01 5 136133474 136133695 222 + 0.272 0.468 1.155
ENSG00000113658 E010 1.2262909 0.0440187949 3.650015e-01 5.093432e-01 5 136133696 136133822 127 + 0.218 0.470 1.581
ENSG00000113658 E011 1.2220245 0.1070400833 3.764274e-01 5.207519e-01 5 136133823 136133911 89 + 0.218 0.469 1.577
ENSG00000113658 E012 0.8973375 0.0514167284 7.940441e-01 8.683839e-01 5 136133912 136133959 48 + 0.188 0.295 0.842
ENSG00000113658 E013 0.1482932 0.0411597534 4.999717e-02   5 136133960 136134035 76 + 0.000 0.295 15.700
ENSG00000113658 E014 0.0000000       5 136147420 136147831 412 +      
ENSG00000113658 E015 14.7450108 0.0033355024 7.329488e-04 3.017885e-03 5 136147832 136147835 4 + 1.057 0.594 -1.830
ENSG00000113658 E016 26.7016277 0.0087425234 9.600537e-06 6.409165e-05 5 136147836 136147906 71 + 1.299 0.769 -1.953
ENSG00000113658 E017 5.1270162 0.0109418777 1.930359e-01 3.175772e-01 5 136152675 136152758 84 + 0.651 0.470 -0.830
ENSG00000113658 E018 252.4988970 0.0002368977 1.102042e-16 4.712834e-15 5 136153592 136154163 572 + 2.234 2.047 -0.626
ENSG00000113658 E019 106.0345719 0.0003110503 4.366923e-03 1.416804e-02 5 136160856 136160985 130 + 1.846 1.816 -0.103
ENSG00000113658 E020 121.2339124 0.0024438623 5.502714e-02 1.180443e-01 5 136160986 136161107 122 + 1.899 1.914 0.051
ENSG00000113658 E021 104.7303671 0.0034569403 2.892409e-02 6.985254e-02 5 136163272 136163391 120 + 1.840 1.828 -0.041
ENSG00000113658 E022 128.7431152 0.0002641568 1.431233e-01 2.522751e-01 5 136172434 136172655 222 + 1.919 1.972 0.178
ENSG00000113658 E023 2.0763978 0.1457094547 5.858984e-02 1.242102e-01 5 136172656 136172829 174 + 0.271 0.822 2.697
ENSG00000113658 E024 82.9991576 0.0003457605 6.354496e-03 1.954366e-02 5 136174376 136174468 93 + 1.742 1.697 -0.152
ENSG00000113658 E025 113.6966688 0.0004374628 2.191554e-02 5.550174e-02 5 136174469 136174632 164 + 1.872 1.876 0.015
ENSG00000113658 E026 1487.0294230 0.0048308257 3.286627e-11 6.288040e-10 5 136177337 136182734 5398 + 2.952 3.167 0.714
ENSG00000113658 E027 0.0000000       5 136187161 136187316 156 +      
ENSG00000113658 E028 0.0000000       5 136188545 136188747 203 +