• ENSG00000112294
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000112294

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000357578 ENSG00000112294 HEK293_OSMI2_2hA HEK293_TMG_2hB ALDH5A1 protein_coding protein_coding 18.22434 20.3051 19.54626 1.426208 0.7717048 -0.05492206 6.244731 2.8232554 11.167017 0.7665401 1.0147173 1.980003 0.33940000 0.13770000 0.57163333 0.4339333 1.897158e-06 1.110688e-07 FALSE TRUE
ENST00000491546 ENSG00000112294 HEK293_OSMI2_2hA HEK293_TMG_2hB ALDH5A1 protein_coding protein_coding 18.22434 20.3051 19.54626 1.426208 0.7717048 -0.05492206 1.751508 0.9339033 2.691023 0.4653380 0.1533475 1.516795 0.09527917 0.04633333 0.13863333 0.0923000 5.304914e-02 1.110688e-07 FALSE TRUE
ENST00000672352 ENSG00000112294 HEK293_OSMI2_2hA HEK293_TMG_2hB ALDH5A1 protein_coding protein_coding 18.22434 20.3051 19.54626 1.426208 0.7717048 -0.05492206 3.121497 6.7034119 1.300904 1.2950177 0.8648191 -2.356484 0.16743333 0.33136667 0.06790000 -0.2634667 2.463623e-01 1.110688e-07 FALSE TRUE
MSTRG.27729.7 ENSG00000112294 HEK293_OSMI2_2hA HEK293_TMG_2hB ALDH5A1 protein_coding   18.22434 20.3051 19.54626 1.426208 0.7717048 -0.05492206 4.080531 7.5390709 1.532659 1.0230569 0.3568227 -2.290880 0.23214583 0.36976667 0.07796667 -0.2918000 1.110688e-07 1.110688e-07 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_2hBColumn filter
HEK293_OSMI2_2hAColumn filter
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hBColumn filter
ENSG00000112294 E001 27.6579291 0.0524126691 1.799875e-01 3.011667e-01 6 24494867 24494968 102 + 1.526 1.386 -0.480
ENSG00000112294 E002 35.9677197 0.0775978864 1.404160e-02 3.831894e-02 6 24494969 24495075 107 + 1.705 1.398 -1.050
ENSG00000112294 E003 40.5206579 0.0779766853 3.033612e-04 1.393098e-03 6 24495076 24495233 158 + 1.813 1.326 -1.664
ENSG00000112294 E004 22.1483984 0.0444821678 5.680498e-05 3.156245e-04 6 24495234 24495235 2 + 1.561 1.075 -1.701
ENSG00000112294 E005 53.3963886 0.0204745792 8.143277e-05 4.347771e-04 6 24495236 24495350 115 + 1.876 1.564 -1.057
ENSG00000112294 E006 2.9392064 0.0281979562 1.405982e-06 1.130412e-05 6 24496820 24496983 164 + 0.867 0.000 -14.448
ENSG00000112294 E007 8.1031871 0.0061988928 1.081166e-05 7.127277e-05 6 24501409 24502522 1114 + 1.157 0.636 -2.006
ENSG00000112294 E008 85.5461080 0.0033592377 4.756256e-01 6.143315e-01 6 24502523 24502606 84 + 1.946 1.932 -0.044
ENSG00000112294 E009 0.1451727 0.0428978704 4.933861e-01   6 24502607 24502763 157 + 0.120 0.000 -9.984
ENSG00000112294 E010 151.2591831 0.0015478573 8.936859e-01 9.359980e-01 6 24503263 24503433 171 + 2.171 2.196 0.086
ENSG00000112294 E011 96.2140339 0.0014508972 3.354801e-01 4.792694e-01 6 24504869 24504899 31 + 1.957 2.017 0.201
ENSG00000112294 E012 114.8709611 0.0008962174 2.795809e-01 4.193447e-01 6 24504900 24504985 86 + 2.074 2.058 -0.053
ENSG00000112294 E013 11.5110964 0.0732866939 5.901543e-01 7.130746e-01 6 24511830 24511868 39 + 1.127 1.060 -0.242
ENSG00000112294 E014 0.4449813 0.0211947182 5.634168e-01 6.908762e-01 6 24515125 24515166 42 + 0.214 0.125 -0.939
ENSG00000112294 E015 137.8095697 0.0026876358 1.434365e-01 2.526969e-01 6 24515167 24515310 144 + 2.163 2.126 -0.124
ENSG00000112294 E016 0.3332198 0.0285042248 1.000000e+00   6 24515311 24515712 402 + 0.120 0.125 0.063
ENSG00000112294 E017 174.2520510 0.0024286833 5.971748e-01 7.189837e-01 6 24520401 24520544 144 + 2.224 2.261 0.124
ENSG00000112294 E018 1.0737433 0.0120085892 6.944319e-01 7.952715e-01 6 24522638 24522766 129 + 0.357 0.300 -0.355
ENSG00000112294 E019 191.3949108 0.0003206345 1.000448e-01 1.905513e-01 6 24522767 24522925 159 + 2.251 2.317 0.218
ENSG00000112294 E020 2.5033911 0.0069477613 1.919995e-02 4.976975e-02 6 24523605 24523942 338 + 0.291 0.698 2.061
ENSG00000112294 E021 198.0944621 0.0002008257 1.920254e-05 1.196180e-04 6 24527997 24528166 170 + 2.228 2.358 0.435
ENSG00000112294 E022 0.5944058 0.4639055541 6.605825e-01 7.692252e-01 6 24532010 24532118 109 + 0.120 0.231 1.135
ENSG00000112294 E023 129.0800241 0.0014222478 7.271453e-07 6.222862e-06 6 24532119 24532177 59 + 2.002 2.200 0.665
ENSG00000112294 E024 192.5931857 0.0002111845 8.627547e-06 5.817422e-05 6 24533507 24533687 181 + 2.212 2.349 0.456
ENSG00000112294 E025 586.3179300 0.0001726030 6.253445e-39 2.007960e-36 6 24533688 24535518 1831 + 2.850 2.689 -0.536
ENSG00000112294 E026 432.3605020 0.0078256644 1.690685e-01 2.869778e-01 6 24535519 24536509 991 + 2.594 2.671 0.256
ENSG00000112294 E027 428.8741622 0.0145316442 2.413771e-04 1.139132e-03 6 24536510 24537207 698 + 2.496 2.725 0.762
ENSG00000112294 E028 3.9749985 0.0041537635 1.478224e-02 4.000357e-02 6 24543128 24543312 185 + 0.464 0.844 1.646