ENSG00000111879

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000338891 ENSG00000111879 HEK293_OSMI2_2hA HEK293_TMG_2hB FAM184A protein_coding protein_coding 4.432195 2.525795 5.768339 0.4123277 0.1431665 1.188217 2.47076848 1.15257155 3.7728241 0.17987315 0.1019929 1.7021442 0.54972083 0.46113333 0.65570000 0.19456667 2.852116e-02 1.856864e-08 FALSE TRUE
ENST00000352896 ENSG00000111879 HEK293_OSMI2_2hA HEK293_TMG_2hB FAM184A protein_coding protein_coding 4.432195 2.525795 5.768339 0.4123277 0.1431665 1.188217 0.44714335 0.17842388 0.4225043 0.09757955 0.2464726 1.1987328 0.10793750 0.06063333 0.07306667 0.01243333 1.000000e+00 1.856864e-08 FALSE TRUE
ENST00000448815 ENSG00000111879 HEK293_OSMI2_2hA HEK293_TMG_2hB FAM184A protein_coding protein_coding 4.432195 2.525795 5.768339 0.4123277 0.1431665 1.188217 0.30607956 0.13714635 0.0954052 0.07472412 0.0954052 -0.4813057 0.06542083 0.04926667 0.01740000 -0.03186667 5.732620e-01 1.856864e-08 FALSE TRUE
ENST00000521043 ENSG00000111879 HEK293_OSMI2_2hA HEK293_TMG_2hB FAM184A protein_coding protein_coding 4.432195 2.525795 5.768339 0.4123277 0.1431665 1.188217 0.03600346 0.17106448 0.0000000 0.17106448 0.0000000 -4.1784316 0.01259167 0.06643333 0.00000000 -0.06643333 6.369966e-01 1.856864e-08 FALSE TRUE
ENST00000522284 ENSG00000111879 HEK293_OSMI2_2hA HEK293_TMG_2hB FAM184A protein_coding protein_coding 4.432195 2.525795 5.768339 0.4123277 0.1431665 1.188217 0.20831135 0.03434902 0.4504677 0.01754003 0.1079750 3.3761258 0.03963333 0.01593333 0.07723333 0.06130000 8.010653e-02 1.856864e-08 FALSE TRUE
ENST00000617072 ENSG00000111879 HEK293_OSMI2_2hA HEK293_TMG_2hB FAM184A protein_coding protein_coding 4.432195 2.525795 5.768339 0.4123277 0.1431665 1.188217 0.28033456 0.61346622 0.0000000 0.09817892 0.0000000 -5.9622395 0.07976667 0.26826667 0.00000000 -0.26826667 1.856864e-08 1.856864e-08 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000111879 E001 0.0000000       6 118959763 118959828 66 -      
ENSG00000111879 E002 0.0000000       6 118959829 118959829 1 -      
ENSG00000111879 E003 0.0000000       6 118959830 118959832 3 -      
ENSG00000111879 E004 5.6151342 0.0127001792 5.538894e-06 3.903455e-05 6 118959833 118959921 89 - 0.486 1.108 2.519
ENSG00000111879 E005 26.4889820 0.0016244883 4.301190e-10 6.817096e-09 6 118959922 118960102 181 - 1.216 1.650 1.499
ENSG00000111879 E006 29.2470234 0.0007643043 1.679302e-06 1.327957e-05 6 118960103 118960184 82 - 1.318 1.635 1.092
ENSG00000111879 E007 3.8687034 0.0042870710 6.600220e-01 7.687339e-01 6 118960769 118960863 95 - 0.633 0.709 0.319
ENSG00000111879 E008 37.4792911 0.0113361428 2.539612e-03 8.882195e-03 6 118961761 118961928 168 - 1.466 1.699 0.793
ENSG00000111879 E009 19.7250064 0.0128374663 4.783735e-03 1.532820e-02 6 118961929 118961963 35 - 1.183 1.451 0.937
ENSG00000111879 E010 1.0966340 0.1274234781 4.197784e-01 5.630422e-01 6 118961964 118961996 33 - 0.349 0.181 -1.250
ENSG00000111879 E011 9.6327243 0.0022958239 1.799520e-02 4.712299e-02 6 118961997 118963920 1924 - 1.069 0.788 -1.059
ENSG00000111879 E012 27.3627860 0.0223332365 2.553371e-02 6.298301e-02 6 118964667 118964771 105 - 1.339 1.562 0.767
ENSG00000111879 E013 26.7193725 0.0007981449 5.612999e-03 1.758647e-02 6 118966835 118966952 118 - 1.330 1.530 0.690
ENSG00000111879 E014 25.9217983 0.0021735618 3.090569e-01 4.513456e-01 6 118974428 118974574 147 - 1.366 1.452 0.295
ENSG00000111879 E015 31.9071896 0.0006721618 5.709955e-01 6.973889e-01 6 118975024 118975208 185 - 1.493 1.467 -0.089
ENSG00000111879 E016 27.5333359 0.0007700459 8.832935e-01 9.293367e-01 6 118975917 118976044 128 - 1.417 1.418 0.004
ENSG00000111879 E017 28.1377341 0.0072668021 6.361226e-01 7.502242e-01 6 118979365 118979518 154 - 1.434 1.413 -0.072
ENSG00000111879 E018 32.2127700 0.0006901187 8.950821e-02 1.743818e-01 6 118980138 118980350 213 - 1.520 1.418 -0.352
ENSG00000111879 E019 27.1380213 0.0033458721 1.050984e-01 1.982335e-01 6 119002899 119003049 151 - 1.447 1.335 -0.388
ENSG00000111879 E020 25.0728509 0.0008182951 1.563981e-02 4.193319e-02 6 119003501 119003622 122 - 1.431 1.255 -0.613
ENSG00000111879 E021 5.4035553 0.0200539861 4.600698e-02 1.020464e-01 6 119005287 119006176 890 - 0.869 0.552 -1.319
ENSG00000111879 E022 30.4755993 0.0007166337 4.414771e-03 1.430467e-02 6 119006447 119006608 162 - 1.523 1.334 -0.654
ENSG00000111879 E023 0.0000000       6 119009549 119009573 25 -      
ENSG00000111879 E024 0.8491631 0.0156131568 6.088435e-01 7.284597e-01 6 119011177 119011308 132 - 0.209 0.307 0.735
ENSG00000111879 E025 13.2777278 0.0017862305 6.739679e-01 7.795230e-01 6 119011309 119011330 22 - 1.139 1.108 -0.112
ENSG00000111879 E026 25.5487735 0.0008391054 4.312403e-01 5.738048e-01 6 119011331 119011431 101 - 1.410 1.364 -0.162
ENSG00000111879 E027 34.8882094 0.0006696205 4.810690e-02 1.058183e-01 6 119016747 119016944 198 - 1.559 1.443 -0.399
ENSG00000111879 E028 31.3825015 0.0006506056 1.235085e-03 4.759625e-03 6 119019978 119020159 182 - 1.539 1.323 -0.744
ENSG00000111879 E029 24.6106099 0.0007754324 4.530319e-01 5.938209e-01 6 119022945 119023080 136 - 1.389 1.344 -0.156
ENSG00000111879 E030 75.5241230 0.0003951817 3.922588e-05 2.265687e-04 6 119023959 119024813 855 - 1.898 1.728 -0.574
ENSG00000111879 E031 17.6834234 0.0012949289 1.720037e-03 6.345781e-03 6 119078141 119078664 524 - 1.318 1.032 -1.018
ENSG00000111879 E032 0.2966881 0.0290785164 5.699307e-01   6 119079005 119079179 175 - 0.150 0.001 -7.928
ENSG00000111879 E033 0.0000000       6 119149078 119149387 310 -