• ENSG00000109133
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000109133

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000264452 ENSG00000109133 HEK293_OSMI2_2hA HEK293_TMG_2hB TMEM33 protein_coding nonsense_mediated_decay 27.31838 11.24985 37.17857 0.6288846 1.037076 1.723672 1.3572308 0.1527960 2.7941879 0.07535255 0.2494904 4.1064456 0.03739167 0.01333333 0.07516667 0.06183333 0.0006313473 0.0006313473    
ENST00000325094 ENSG00000109133 HEK293_OSMI2_2hA HEK293_TMG_2hB TMEM33 protein_coding protein_coding 27.31838 11.24985 37.17857 0.6288846 1.037076 1.723672 7.2582387 4.9434935 9.5762560 0.86673652 0.1607897 0.9525211 0.31094583 0.44573333 0.25813333 -0.18760000 0.1717777205 0.0006313473 TRUE  
ENST00000504986 ENSG00000109133 HEK293_OSMI2_2hA HEK293_TMG_2hB TMEM33 protein_coding protein_coding 27.31838 11.24985 37.17857 0.6288846 1.037076 1.723672 6.3642666 2.2828539 10.1099367 0.31068962 0.5065015 2.1419839 0.22015000 0.20593333 0.27160000 0.06566667 0.4068173348 0.0006313473 FALSE  
ENST00000513558 ENSG00000109133 HEK293_OSMI2_2hA HEK293_TMG_2hB TMEM33 protein_coding protein_coding 27.31838 11.24985 37.17857 0.6288846 1.037076 1.723672 0.4877399 0.9102536 0.3082329 0.44750954 0.1562857 -1.5319484 0.02951667 0.08350000 0.00810000 -0.07540000 0.0921721521 0.0006313473 FALSE  
ENST00000513702 ENSG00000109133 HEK293_OSMI2_2hA HEK293_TMG_2hB TMEM33 protein_coding protein_coding 27.31838 11.24985 37.17857 0.6288846 1.037076 1.723672 1.4568738 0.1894394 2.4911755 0.03723970 0.3922829 3.6485841 0.04023750 0.01676667 0.06716667 0.05040000 0.0006383131 0.0006313473 FALSE  
MSTRG.24789.8 ENSG00000109133 HEK293_OSMI2_2hA HEK293_TMG_2hB TMEM33 protein_coding   27.31838 11.24985 37.17857 0.6288846 1.037076 1.723672 8.9302533 2.5812265 9.2035250 1.87914746 0.3506107 1.8301181 0.31648750 0.21766667 0.24750000 0.02983333 0.8120370079 0.0006313473 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_2hBColumn filter
HEK293_OSMI2_2hAColumn filter
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hBColumn filter
ENSG00000109133 E001 11.3122263 0.0093797229 1.985701e-01 3.244010e-01 4 41935129 41935151 23 + 1.102 0.950 -0.557
ENSG00000109133 E002 124.5717793 0.0023717231 6.635832e-01 7.715914e-01 4 41935152 41935262 111 + 2.074 2.058 -0.053
ENSG00000109133 E003 118.3417396 0.0049856757 3.549614e-01 4.993049e-01 4 41935263 41935310 48 + 2.032 2.077 0.149
ENSG00000109133 E004 132.6949805 0.0022939497 1.234112e-02 3.435137e-02 4 41935311 41935383 73 + 2.062 2.163 0.338
ENSG00000109133 E005 118.1203829 0.0002422994 1.477927e-03 5.565936e-03 4 41935384 41935428 45 + 2.009 2.123 0.384
ENSG00000109133 E006 95.8678953 0.0002993347 1.138395e-01 2.111160e-01 4 41935429 41935443 15 + 1.934 2.001 0.223
ENSG00000109133 E007 99.5882843 0.0002954494 1.302868e-02 3.597919e-02 4 41935444 41935466 23 + 1.939 2.038 0.331
ENSG00000109133 E008 154.9713606 0.0033777837 7.628818e-02 1.535645e-01 4 41935467 41935529 63 + 2.139 2.211 0.240
ENSG00000109133 E009 187.1649812 0.0005433631 4.337726e-01 5.761788e-01 4 41938602 41938696 95 + 2.237 2.264 0.092
ENSG00000109133 E010 164.1625559 0.0002438381 5.037416e-01 6.396973e-01 4 41939196 41939254 59 + 2.180 2.205 0.085
ENSG00000109133 E011 271.4362113 0.0002498317 7.452556e-01 8.333602e-01 4 41939255 41939383 129 + 2.407 2.404 -0.009
ENSG00000109133 E012 3.0217079 0.0058670036 8.960461e-03 2.618033e-02 4 41939721 41939828 108 + 0.683 0.184 -2.854
ENSG00000109133 E013 227.6822908 0.0001964894 6.176762e-01 7.354420e-01 4 41943747 41943814 68 + 2.324 2.342 0.060
ENSG00000109133 E014 1.1982920 0.1173687416 3.586839e-01 5.030552e-01 4 41943815 41944202 388 + 0.382 0.183 -1.428
ENSG00000109133 E015 302.9195731 0.0012813461 1.566114e-01 2.705866e-01 4 41944793 41944926 134 + 2.439 2.478 0.131
ENSG00000109133 E016 251.1656166 0.0002221008 4.820521e-02 1.059964e-01 4 41949302 41949385 84 + 2.354 2.407 0.176
ENSG00000109133 E017 3.3663724 0.0054124538 6.999532e-04 2.898956e-03 4 41953760 41954069 310 + 0.381 0.895 2.286
ENSG00000109133 E018 1473.0666817 0.0014304538 1.137798e-17 5.541195e-16 4 41954070 41958173 4104 + 3.175 3.041 -0.445
ENSG00000109133 E019 192.0836528 0.0002174391 4.253922e-09 5.611285e-08 4 41958174 41958871 698 + 2.301 2.134 -0.561
ENSG00000109133 E020 669.4784845 0.0176695397 6.502571e-03 1.992902e-02 4 41958872 41960803 1932 + 2.731 2.909 0.592
ENSG00000109133 E021 0.7415557 0.1095412212 7.189739e-01 8.139570e-01 4 41978134 41978282 149 + 0.256 0.183 -0.616