ENSG00000107902

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000368842 ENSG00000107902 HEK293_OSMI2_2hA HEK293_TMG_2hB LHPP protein_coding protein_coding 17.14215 29.22652 12.36343 0.7728595 0.7589335 -1.240526 8.093779 14.294133 4.9361912 0.1539454 0.1534082 -1.532042 0.45605000 0.48976667 0.40286667 -0.086900000 0.22549855 0.01200017 FALSE TRUE
ENST00000392757 ENSG00000107902 HEK293_OSMI2_2hA HEK293_TMG_2hB LHPP protein_coding protein_coding 17.14215 29.22652 12.36343 0.7728595 0.7589335 -1.240526 5.737691 9.263818 5.7458282 0.8854798 0.6371037 -0.688140 0.34063333 0.31580000 0.46216667 0.146366667 0.01200017 0.01200017 FALSE TRUE
ENST00000481452 ENSG00000107902 HEK293_OSMI2_2hA HEK293_TMG_2hB LHPP protein_coding processed_transcript 17.14215 29.22652 12.36343 0.7728595 0.7589335 -1.240526 1.194932 2.019969 0.1108554 0.3143424 0.1108554 -4.070104 0.07427917 0.06970000 0.01023333 -0.059466667 0.08540385 0.01200017 FALSE FALSE
ENST00000487190 ENSG00000107902 HEK293_OSMI2_2hA HEK293_TMG_2hB LHPP protein_coding processed_transcript 17.14215 29.22652 12.36343 0.7728595 0.7589335 -1.240526 1.458322 2.686112 1.1211110 0.1782423 0.5307485 -1.253140 0.08636250 0.09176667 0.08893333 -0.002833333 0.88177817 0.01200017   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000107902 E001 3.7172091 0.0499179618 0.5648014536 0.6920232376 10 124461823 124461833 11 + 0.677 0.580 -0.424
ENSG00000107902 E002 9.2747224 0.0980731223 0.1531172148 0.2659076258 10 124461834 124461842 9 + 1.108 0.874 -0.867
ENSG00000107902 E003 88.7090825 0.0158595561 0.1268005295 0.2296973630 10 124461843 124461987 145 + 1.952 1.853 -0.334
ENSG00000107902 E004 197.2158890 0.0009617005 0.0028987877 0.0099660032 10 124484139 124484326 188 + 2.285 2.202 -0.276
ENSG00000107902 E005 109.0340764 0.0003613956 0.0058801121 0.0182968907 10 124488422 124488428 7 + 2.039 1.942 -0.326
ENSG00000107902 E006 133.8182417 0.0005534571 0.0335973143 0.0789612744 10 124488429 124488462 34 + 2.106 2.038 -0.229
ENSG00000107902 E007 176.4849743 0.0002795955 0.0479873024 0.1056153267 10 124488463 124488575 113 + 2.217 2.164 -0.176
ENSG00000107902 E008 8.9400372 0.0019278867 0.5515796853 0.6810094596 10 124493720 124493877 158 + 0.872 0.949 0.294
ENSG00000107902 E009 116.9262608 0.0002821852 0.8334900033 0.8956935249 10 124496961 124497024 64 + 1.992 2.004 0.040
ENSG00000107902 E010 152.6083729 0.0034061272 0.0874766993 0.1713101186 10 124498036 124498128 93 + 2.058 2.134 0.256
ENSG00000107902 E011 32.0026277 0.0060977706 0.3366215182 0.4804962046 10 124498328 124498514 187 + 1.391 1.474 0.287
ENSG00000107902 E012 101.7911696 0.0019841373 0.0001398094 0.0007027638 10 124517180 124517271 92 + 1.797 1.980 0.614
ENSG00000107902 E013 2.3970273 0.0068509905 0.0834658365 0.1649800960 10 124517272 124517376 105 + 0.187 0.528 2.143
ENSG00000107902 E014 0.0000000       10 124545984 124546024 41 +      
ENSG00000107902 E015 0.0000000       10 124546025 124546189 165 +      
ENSG00000107902 E016 0.1817044 0.0402939466 1.0000000000   10 124605200 124605515 316 + 0.000 0.078 7.876
ENSG00000107902 E017 0.2955422 0.0294415035 0.4608043854   10 124612833 124612950 118 + 0.187 0.078 -1.446
ENSG00000107902 E018 57.4246805 0.0025360528 0.0017037215 0.0062946416 10 124613264 124613302 39 + 1.542 1.738 0.668
ENSG00000107902 E019 209.8190976 0.0039241249 0.0019442390 0.0070534325 10 124613303 124614141 839 + 2.154 2.279 0.416
ENSG00000107902 E020 9.7864722 0.0523886703 0.1431255656 0.2522767867 10 124616538 124617888 1351 + 1.107 0.898 -0.775