ENSG00000107372

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000343431 ENSG00000107372 HEK293_OSMI2_2hA HEK293_TMG_2hB ZFAND5 protein_coding protein_coding 38.97763 24.95284 56.62026 0.1721304 1.849032 1.181791 4.851469 1.9966015 7.838889 0.1678422 0.3148722 1.9677344 0.1193667 0.08010000 0.1385667 0.05846667 0.0008674912 4.626985e-07 FALSE TRUE
ENST00000376960 ENSG00000107372 HEK293_OSMI2_2hA HEK293_TMG_2hB ZFAND5 protein_coding protein_coding 38.97763 24.95284 56.62026 0.1721304 1.849032 1.181791 22.520844 18.6867578 30.949115 1.2842455 1.3813616 0.7275761 0.6089250 0.74893333 0.5471667 -0.20176667 0.0389734236 4.626985e-07 FALSE TRUE
ENST00000471197 ENSG00000107372 HEK293_OSMI2_2hA HEK293_TMG_2hB ZFAND5 protein_coding processed_transcript 38.97763 24.95284 56.62026 0.1721304 1.849032 1.181791 5.645718 2.4400995 7.729646 1.5713948 1.2381259 1.6594272 0.1332667 0.09760000 0.1360000 0.03840000 0.7586523584 4.626985e-07 FALSE FALSE
ENST00000488164 ENSG00000107372 HEK293_OSMI2_2hA HEK293_TMG_2hB ZFAND5 protein_coding processed_transcript 38.97763 24.95284 56.62026 0.1721304 1.849032 1.181791 2.678033 0.6256898 3.582536 0.1674968 0.1975131 2.4986078 0.0616125 0.02506667 0.0632000 0.03813333 0.0070632552 4.626985e-07 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000107372 E001 0.7665478 0.0250261963 4.606652e-01 6.006596e-01 9 72351413 72351424 12 - 0.283 0.164 -1.000
ENSG00000107372 E002 113.8636147 0.0028441375 1.648734e-01 2.815339e-01 9 72351425 72354457 3033 - 2.053 2.037 -0.052
ENSG00000107372 E003 1282.2959264 0.0026584535 7.215115e-10 1.099664e-08 9 72354458 72355832 1375 - 3.030 3.186 0.519
ENSG00000107372 E004 204.6182151 0.0002516477 1.747139e-02 4.598174e-02 9 72355833 72355954 122 - 2.258 2.360 0.341
ENSG00000107372 E005 209.2075917 0.0044226663 1.709415e-01 2.894045e-01 9 72355955 72356040 86 - 2.272 2.363 0.304
ENSG00000107372 E006 242.3607977 0.0002221704 5.580050e-01 6.863198e-01 9 72356041 72356101 61 - 2.362 2.390 0.094
ENSG00000107372 E007 192.0868470 0.0002473761 1.470788e-01 2.577150e-01 9 72356931 72356945 15 - 2.271 2.275 0.011
ENSG00000107372 E008 318.1192985 0.0002258255 6.442789e-01 7.566170e-01 9 72356946 72357056 111 - 2.479 2.511 0.108
ENSG00000107372 E009 283.9388098 0.0002005731 4.908821e-01 6.282066e-01 9 72359418 72359521 104 - 2.421 2.478 0.189
ENSG00000107372 E010 221.7603692 0.0001681886 3.905291e-01 5.344894e-01 9 72360110 72360221 112 - 2.328 2.349 0.071
ENSG00000107372 E011 18.0487791 0.0014274401 1.467889e-01 2.573023e-01 9 72360222 72360285 64 - 1.197 1.355 0.553
ENSG00000107372 E012 7.4104027 0.0049854799 1.865200e-06 1.461117e-05 9 72360438 72360627 190 - 1.064 0.377 -2.940
ENSG00000107372 E013 219.3358718 0.0001760255 2.265547e-10 3.757669e-09 9 72360628 72360784 157 - 2.371 2.253 -0.394
ENSG00000107372 E014 89.3422268 0.0002894774 2.404384e-10 3.971605e-09 9 72360785 72360787 3 - 2.013 1.797 -0.727
ENSG00000107372 E015 110.4588696 0.0024942434 3.096042e-10 5.027307e-09 9 72363470 72363606 137 - 2.108 1.873 -0.790
ENSG00000107372 E016 27.7951677 0.0006712150 5.933569e-13 1.509998e-11 9 72363607 72364346 740 - 1.583 1.046 -1.882
ENSG00000107372 E017 2.8819596 0.0061114111 1.349566e-02 3.706829e-02 9 72364462 72364695 234 - 0.691 0.283 -2.089
ENSG00000107372 E018 194.4756056 0.0017242332 1.343477e-22 1.143900e-20 9 72364696 72365235 540 - 2.366 2.069 -0.993