ENSG00000107262

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000379704 ENSG00000107262 HEK293_OSMI2_2hA HEK293_TMG_2hB BAG1 protein_coding protein_coding 53.0722 62.2921 50.42732 8.923089 1.554338 -0.3047892 45.462924 55.344655 41.737420 8.0260920 1.5849503 -0.4070176 0.85415833 0.888 0.82736667 -0.06063333 0.0001905335 0.0001905335 FALSE  
ENST00000634734 ENSG00000107262 HEK293_OSMI2_2hA HEK293_TMG_2hB BAG1 protein_coding protein_coding 53.0722 62.2921 50.42732 8.923089 1.554338 -0.3047892 2.784517 2.662484 3.502811 0.3171842 0.1182013 0.3944445 0.05359167 0.043 0.06963333 0.02663333 0.0025012168 0.0001905335 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000107262 E001 11.511113 0.0209593738 8.951031e-01 9.369694e-01 9 33247820 33248166 347 - 1.069 1.079 0.038
ENSG00000107262 E002 3.126957 0.0065123767 8.425091e-01 9.018714e-01 9 33248312 33248324 13 - 0.620 0.595 -0.111
ENSG00000107262 E003 4.942369 0.0550700026 5.839323e-01 7.079461e-01 9 33248325 33248421 97 - 0.817 0.722 -0.378
ENSG00000107262 E004 209.731730 0.0005329928 5.443760e-17 2.415798e-15 9 33252471 33255024 2554 - 2.434 2.224 -0.701
ENSG00000107262 E005 18.019680 0.0011655971 1.958397e-02 5.059353e-02 9 33255025 33255025 1 - 1.373 1.195 -0.623
ENSG00000107262 E006 43.509712 0.0013056169 4.597445e-01 5.998456e-01 9 33255026 33255048 23 - 1.657 1.624 -0.114
ENSG00000107262 E007 538.335148 0.0010897064 8.664448e-07 7.294053e-06 9 33255049 33255308 260 - 2.649 2.754 0.350
ENSG00000107262 E008 2.296794 0.2739225260 6.761305e-02 1.393883e-01 9 33255864 33255864 1 - 0.145 0.622 3.005
ENSG00000107262 E009 429.768283 0.0001644255 9.063547e-07 7.594594e-06 9 33255865 33255927 63 - 2.563 2.658 0.317
ENSG00000107262 E010 524.108986 0.0011027870 6.623791e-05 3.619192e-04 9 33256801 33256908 108 - 2.650 2.737 0.287
ENSG00000107262 E011 6.686677 0.0025843944 5.930031e-01 7.154626e-01 9 33256909 33257671 763 - 0.911 0.854 -0.218
ENSG00000107262 E012 1.344494 0.3031675854 4.351089e-01 5.773465e-01 9 33257720 33258123 404 - 0.476 0.260 -1.286
ENSG00000107262 E013 1.221094 0.0108647759 5.662868e-03 1.772157e-02 9 33258919 33258919 1 - 0.577 0.103 -3.378
ENSG00000107262 E014 572.905894 0.0001881093 2.009808e-02 5.169398e-02 9 33258920 33259033 114 - 2.722 2.766 0.144
ENSG00000107262 E015 9.894292 0.0016970172 3.504159e-02 8.172985e-02 9 33259034 33259884 851 - 1.149 0.941 -0.758
ENSG00000107262 E016 5.099186 0.0031234316 1.720526e-02 4.539546e-02 9 33259885 33260488 604 - 0.951 0.650 -1.194
ENSG00000107262 E017 446.138629 0.0001314124 8.548988e-01 9.102446e-01 9 33261087 33261169 83 - 2.635 2.646 0.037
ENSG00000107262 E018 15.838188 0.0012359177 2.754130e-06 2.078980e-05 9 33262105 33262217 113 - 1.421 1.036 -1.362
ENSG00000107262 E019 7.723714 0.0077612651 7.581817e-03 2.272458e-02 9 33262218 33262246 29 - 1.097 0.784 -1.179
ENSG00000107262 E020 314.368964 0.0019862731 6.440219e-01 7.564372e-01 9 33262702 33262740 39 - 2.494 2.483 -0.037
ENSG00000107262 E021 412.882619 0.0009612629 2.562550e-01 3.932216e-01 9 33262741 33262830 90 - 2.619 2.600 -0.064
ENSG00000107262 E022 5.888707 0.0303503906 9.387687e-01 9.655432e-01 9 33264206 33264223 18 - 0.817 0.848 0.122
ENSG00000107262 E023 311.538835 0.0003943229 1.891083e-01 3.126151e-01 9 33264224 33264275 52 - 2.500 2.480 -0.065
ENSG00000107262 E024 470.769878 0.0001758332 9.391497e-15 3.100716e-13 9 33264276 33264720 445 - 2.736 2.617 -0.397