ENSG00000107164

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000319725 ENSG00000107164 HEK293_OSMI2_2hA HEK293_TMG_2hB FUBP3 protein_coding protein_coding 37.33682 28.13721 56.53651 4.882998 1.116567 1.006446 28.7785158 18.539722 44.7864345 2.4621945 2.53768128 1.271986 0.74592500 0.66763333 0.791166667 0.12353333 9.443392e-02 4.893776e-05 FALSE TRUE
ENST00000472006 ENSG00000107164 HEK293_OSMI2_2hA HEK293_TMG_2hB FUBP3 protein_coding processed_transcript 37.33682 28.13721 56.53651 4.882998 1.116567 1.006446 1.3903443 4.340215 0.2244029 2.5019339 0.05033019 -4.214024 0.05607083 0.13380000 0.003966667 -0.12983333 4.893776e-05 4.893776e-05   FALSE
ENST00000492199 ENSG00000107164 HEK293_OSMI2_2hA HEK293_TMG_2hB FUBP3 protein_coding processed_transcript 37.33682 28.13721 56.53651 4.882998 1.116567 1.006446 0.5065234 1.733172 0.1754665 0.5615596 0.02547895 -3.232484 0.02126250 0.07153333 0.003100000 -0.06843333 6.711748e-04 4.893776e-05   FALSE
MSTRG.33523.4 ENSG00000107164 HEK293_OSMI2_2hA HEK293_TMG_2hB FUBP3 protein_coding   37.33682 28.13721 56.53651 4.882998 1.116567 1.006446 3.5106989 1.521901 5.9525554 0.1321729 0.62421957 1.960608 0.09343750 0.05600000 0.105266667 0.04926667 1.266792e-02 4.893776e-05 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000107164 E001 0.000000       9 130577354 130578581 1228 +      
ENSG00000107164 E002 0.000000       9 130578582 130578964 383 +      
ENSG00000107164 E003 3.265418 0.0047616114 1.262034e-04 6.421781e-04 9 130578965 130579576 612 + 0.749 0.000 -12.550
ENSG00000107164 E004 3.419010 0.0091744943 1.006518e-04 5.248893e-04 9 130579577 130579580 4 + 0.765 0.000 -12.613
ENSG00000107164 E005 169.302171 0.0110156900 8.410378e-05 4.474912e-04 9 130579581 130579764 184 + 2.270 2.042 -0.762
ENSG00000107164 E006 10.624957 0.0045875734 4.620133e-01 6.019245e-01 9 130580659 130581094 436 + 1.060 1.004 -0.207
ENSG00000107164 E007 11.545162 0.0018638163 2.754389e-03 9.534969e-03 9 130581095 130581513 419 + 0.953 1.271 1.148
ENSG00000107164 E008 3.535431 0.1289192092 1.325785e-02 3.651950e-02 9 130581514 130582086 573 + 0.393 0.907 2.265
ENSG00000107164 E009 247.751924 0.0024387275 7.763862e-08 8.054544e-07 9 130595483 130595588 106 + 2.420 2.254 -0.556
ENSG00000107164 E010 4.909981 0.0033384679 6.699977e-01 7.766094e-01 9 130607298 130608393 1096 + 0.733 0.816 0.334
ENSG00000107164 E011 147.011153 0.0005013057 2.749703e-09 3.761448e-08 9 130609954 130609956 3 + 2.198 2.021 -0.591
ENSG00000107164 E012 198.443299 0.0001916796 4.683168e-11 8.736703e-10 9 130609957 130609987 31 + 2.324 2.166 -0.528
ENSG00000107164 E013 248.592787 0.0001833141 4.113905e-11 7.738724e-10 9 130612456 130612505 50 + 2.416 2.278 -0.461
ENSG00000107164 E014 298.162814 0.0002001112 4.482364e-05 2.554895e-04 9 130612956 130613027 72 + 2.475 2.410 -0.214
ENSG00000107164 E015 274.596032 0.0002061475 1.501428e-02 4.052041e-02 9 130614288 130614345 58 + 2.428 2.399 -0.096
ENSG00000107164 E016 464.126978 0.0005138790 1.123050e-03 4.380451e-03 9 130616355 130616517 163 + 2.659 2.619 -0.132
ENSG00000107164 E017 417.763437 0.0001197475 9.421949e-04 3.761850e-03 9 130617797 130617895 99 + 2.611 2.578 -0.110
ENSG00000107164 E018 321.893861 0.0001447631 3.324052e-04 1.510055e-03 9 130620354 130620413 60 + 2.503 2.455 -0.160
ENSG00000107164 E019 289.653616 0.0001756641 2.097978e-07 2.003305e-06 9 130620414 130620458 45 + 2.469 2.378 -0.305
ENSG00000107164 E020 388.708861 0.0001511365 4.671160e-02 1.033157e-01 9 130622708 130622810 103 + 2.573 2.563 -0.032
ENSG00000107164 E021 311.171951 0.0001448438 9.373853e-01 9.646317e-01 9 130623611 130623711 101 + 2.465 2.492 0.091
ENSG00000107164 E022 372.794172 0.0001728508 5.174792e-01 6.518580e-01 9 130626364 130626505 142 + 2.547 2.562 0.053
ENSG00000107164 E023 349.267121 0.0009805669 4.424715e-01 5.840833e-01 9 130630628 130630788 161 + 2.520 2.527 0.025
ENSG00000107164 E024 6.979165 0.0036369531 4.405855e-01 5.822648e-01 9 130631161 130631293 133 + 0.837 0.958 0.460
ENSG00000107164 E025 235.191746 0.0002397045 2.068461e-01 3.347746e-01 9 130631557 130631630 74 + 2.332 2.393 0.202
ENSG00000107164 E026 241.593984 0.0002466015 6.445491e-01 7.568245e-01 9 130631942 130632022 81 + 2.351 2.392 0.136
ENSG00000107164 E027 234.824092 0.0002136076 1.679283e-02 4.448073e-02 9 130632202 130632278 77 + 2.362 2.330 -0.105
ENSG00000107164 E028 7.483708 0.0023102436 6.273658e-01 7.431723e-01 9 130634621 130634666 46 + 0.875 0.958 0.314
ENSG00000107164 E029 162.674585 0.0067110568 5.302488e-01 6.628879e-01 9 130634667 130634738 72 + 2.190 2.191 0.000
ENSG00000107164 E030 7.415914 0.0869340369 7.242497e-01 8.178324e-01 9 130635864 130635998 135 + 0.863 0.946 0.315
ENSG00000107164 E031 271.137463 0.0017603711 4.166984e-02 9.413466e-02 9 130635999 130636126 128 + 2.424 2.389 -0.116
ENSG00000107164 E032 1219.832614 0.0010057931 6.713040e-74 1.115584e-70 9 130637014 130638352 1339 + 2.932 3.248 1.048