ENSG00000105771

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-5 / 5
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC

ENST00000594081	ENSG00000105771	HEK293_OSMI2_2hA	HEK293_TMG_2hB	SMG9	protein_coding	retained_intron	43.96476	67.08224	25.43353	1.797243	1.20073	-1.398847	2.409710	2.517550	1.316837	0.2341205	0.2671201	-0.9297489	0.05512917	0.03776667	0.05113333	0.01336667	0.5868359	0.0001049036
ENST00000598860	ENSG00000105771	HEK293_OSMI2_2hA	HEK293_TMG_2hB	SMG9	protein_coding	retained_intron	43.96476	67.08224	25.43353	1.797243	1.20073	-1.398847	4.723549	4.910084	3.418402	0.3795259	0.5669184	-0.5211467	0.11878750	0.07303333	0.13286667	0.05983333	0.0119450	0.0001049036	FALSE
ENST00000600097	ENSG00000105771	HEK293_OSMI2_2hA	HEK293_TMG_2hB	SMG9	protein_coding	retained_intron	43.96476	67.08224	25.43353	1.797243	1.20073	-1.398847	3.602286	7.755536	1.730345	1.0088888	0.1885778	-2.1577120	0.06855833	0.11580000	0.06890000	-0.04690000	0.1488349	0.0001049036	FALSE
MSTRG.17255.2	ENSG00000105771	HEK293_OSMI2_2hA	HEK293_TMG_2hB	SMG9	protein_coding		43.96476	67.08224	25.43353	1.797243	1.20073	-1.398847	17.531625	29.767197	9.574562	1.2076387	0.3166747	-1.6354236	0.38474167	0.44343333	0.37820000	-0.06523333	0.1907161	0.0001049036	FALSE
MSTRG.17255.3	ENSG00000105771	HEK293_OSMI2_2hA	HEK293_TMG_2hB	SMG9	protein_coding		43.96476	67.08224	25.43353	1.797243	1.20073	-1.398847	11.405298	18.175639	5.722323	0.6124224	0.1761224	-1.6656080	0.26074583	0.27116667	0.22610000	-0.04506667	0.2534921	0.0001049036	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000105771	E001	80.2445459	0.0015195486	2.973693e-02	7.144035e-02	19	43727983	43731170	3188	-	1.894	1.793	-0.339
ENSG00000105771	E002	196.5494770	0.0033516706	1.245330e-02	3.462619e-02	19	43731171	43731298	128	-	2.111	2.224	0.375
ENSG00000105771	E003	261.0177477	0.0018115572	5.798681e-08	6.161205e-07	19	43731299	43731389	91	-	2.162	2.358	0.656
ENSG00000105771	E004	680.6759489	0.0010981227	1.337942e-08	1.610759e-07	19	43731390	43731674	285	-	2.631	2.763	0.439
ENSG00000105771	E005	16.5477255	0.0028977458	1.107035e-04	5.710985e-04	19	43732270	43732857	588	-	1.398	1.054	-1.219
ENSG00000105771	E006	510.5259109	0.0006233098	4.239470e-03	1.381202e-02	19	43732858	43733002	145	-	2.562	2.628	0.221
ENSG00000105771	E007	2.2069196	0.0070600287	2.345402e-01	3.678041e-01	19	43733003	43733110	108	-	0.594	0.389	-1.017
ENSG00000105771	E008	252.7657109	0.0001942136	1.494884e-02	4.037081e-02	19	43733324	43733343	20	-	2.252	2.322	0.236
ENSG00000105771	E009	370.7847884	0.0002043679	1.253509e-01	2.276439e-01	19	43733344	43733423	80	-	2.446	2.484	0.127
ENSG00000105771	E010	228.2000350	0.0002622146	7.390306e-01	8.287731e-01	19	43733424	43733452	29	-	2.257	2.270	0.043
ENSG00000105771	E011	2.4659432	0.0189259380	5.976321e-02	1.262147e-01	19	43733453	43733474	22	-	0.708	0.389	-1.503
ENSG00000105771	E012	347.3061867	0.0001759729	2.578428e-01	3.950215e-01	19	43733626	43733733	108	-	2.423	2.452	0.098
ENSG00000105771	E013	19.6320426	0.0069180202	6.682216e-02	1.380960e-01	19	43733734	43734079	346	-	1.356	1.189	-0.586
ENSG00000105771	E014	270.7514756	0.0003414875	9.258047e-01	9.572799e-01	19	43734389	43734459	71	-	2.337	2.338	0.003
ENSG00000105771	E015	202.3457342	0.0002047462	9.405283e-01	9.666479e-01	19	43734460	43734495	36	-	2.208	2.214	0.019
ENSG00000105771	E016	26.9794095	0.0054767154	2.125624e-05	1.309742e-04	19	43734496	43734588	93	-	1.592	1.264	-1.132
ENSG00000105771	E017	44.5827760	0.0033854908	3.243308e-08	3.627553e-07	19	43734589	43734825	237	-	1.804	1.467	-1.146
ENSG00000105771	E018	296.9620004	0.0003117877	4.532820e-01	5.940172e-01	19	43737597	43737682	86	-	2.390	2.374	-0.053
ENSG00000105771	E019	10.8017581	0.0370196931	7.751456e-08	8.042995e-07	19	43737850	43738121	272	-	1.427	0.716	-2.617
ENSG00000105771	E020	331.3081902	0.0006089888	7.037793e-02	1.439790e-01	19	43738122	43738217	96	-	2.458	2.415	-0.141
ENSG00000105771	E021	6.6061762	0.0139569441	1.700693e-02	4.494918e-02	19	43739673	43740106	434	-	1.040	0.726	-1.206
ENSG00000105771	E022	324.5761624	0.0001829686	1.379693e-03	5.239941e-03	19	43740107	43740218	112	-	2.472	2.401	-0.236
ENSG00000105771	E023	242.6304488	0.0002338924	1.852233e-01	3.077665e-01	19	43744772	43744884	113	-	2.319	2.286	-0.110
ENSG00000105771	E024	157.4233193	0.0002598558	2.553680e-02	6.298981e-02	19	43747442	43747478	37	-	2.162	2.091	-0.236
ENSG00000105771	E025	166.1663781	0.0002296665	7.557994e-02	1.524401e-01	19	43747479	43747539	61	-	2.170	2.116	-0.181
ENSG00000105771	E026	131.2587118	0.0002521996	3.785358e-01	5.228304e-01	19	43747633	43747654	22	-	2.048	2.019	-0.098
ENSG00000105771	E027	116.9351954	0.0002621499	3.068241e-01	4.490090e-01	19	43747655	43747676	22	-	2.005	1.969	-0.122
ENSG00000105771	E028	132.1396487	0.0002800694	2.687666e-01	4.072516e-01	19	43747677	43747761	85	-	2.057	2.020	-0.125
ENSG00000105771	E029	66.5734288	0.0049408849	7.390541e-01	8.287848e-01	19	43747762	43747776	15	-	1.744	1.729	-0.051
ENSG00000105771	E030	69.7016313	0.0004301763	7.760613e-01	8.558169e-01	19	43747777	43747796	20	-	1.762	1.751	-0.038
ENSG00000105771	E031	164.2624682	0.0003076086	3.694123e-01	5.138292e-01	19	43747797	43747897	101	-	2.146	2.119	-0.089
ENSG00000105771	E032	1.2459699	0.0512253814	2.890698e-01	4.297427e-01	19	43747898	43747977	80	-	0.440	0.238	-1.268
ENSG00000105771	E033	158.1466415	0.0002571061	1.401114e-01	2.481739e-01	19	43747978	43748052	75	-	2.144	2.098	-0.154
ENSG00000105771	E034	201.0764097	0.0030767357	2.767991e-01	4.162764e-01	19	43750592	43750747	156	-	2.243	2.202	-0.135
ENSG00000105771	E035	0.0000000				19	43754376	43754377	2	-
ENSG00000105771	E036	0.0000000				19	43754378	43754529	152	-
ENSG00000105771	E037	0.0000000				19	43754530	43754541	12	-
ENSG00000105771	E038	0.0000000				19	43754542	43754563	22	-
ENSG00000105771	E039	0.7446882	0.4988725998	9.214141e-01	9.544019e-01	19	43754564	43754653	90	-	0.201	0.224	0.195
ENSG00000105771	E040	246.7963388	0.0052973468	9.581071e-03	2.773566e-02	19	43754654	43755050	397	-	2.382	2.274	-0.361

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000105771

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3