ENSG00000105372

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000598261 ENSG00000105372 HEK293_OSMI2_2hA HEK293_TMG_2hB RPS19 protein_coding protein_coding 3442.997 6540.798 1917.163 85.35902 19.95688 -1.770488 1190.076 2339.766 412.7499 115.90864 40.27061 -2.502996 0.3336500 0.3582333 0.2150667 -0.14316667 0.001818213 1.657057e-05 FALSE FALSE
ENST00000598742 ENSG00000105372 HEK293_OSMI2_2hA HEK293_TMG_2hB RPS19 protein_coding protein_coding 3442.997 6540.798 1917.163 85.35902 19.95688 -1.770488 939.712 1856.964 495.4715 12.12189 13.71831 -1.906051 0.2691208 0.2840000 0.2585333 -0.02546667 0.273196943 1.657057e-05 FALSE FALSE
ENST00000601492 ENSG00000105372 HEK293_OSMI2_2hA HEK293_TMG_2hB RPS19 protein_coding protein_coding 3442.997 6540.798 1917.163 85.35902 19.95688 -1.770488 1268.256 2263.517 983.6401 193.02231 44.00840 -1.202355 0.3842208 0.3454667 0.5132667 0.16780000 0.003201239 1.657057e-05 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

No results under this category.

Splicing

All exons whithin this gene region are shown and numbering below.

No results under this category.

Transcripts

All isoforms whithin this gene region are shown below.

No results under this category.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000105372 E001 882.348473 6.026653e-04 3.162083e-13 8.370086e-12 19 41859863 41860254 392 +      
ENSG00000105372 E002 831.802865 5.468641e-04 4.999979e-13 1.287524e-11 19 41860255 41860256 2 +      
ENSG00000105372 E003 17012.275789 1.166597e-03 1.795524e-01 3.005820e-01 19 41860257 41860277 21 +      
ENSG00000105372 E004 22674.963074 7.689298e-04 4.397782e-01 5.815180e-01 19 41860278 41860289 12 +      
ENSG00000105372 E005 224.853159 9.309550e-03 2.067280e-03 7.432768e-03 19 41860290 41860445 156 +      
ENSG00000105372 E006 56.880642 4.079421e-04 2.323615e-01 3.652430e-01 19 41860446 41860494 49 +      
ENSG00000105372 E007 23185.790235 8.129370e-04 3.623147e-01 5.067025e-01 19 41860775 41860777 3 +      
ENSG00000105372 E008 24535.774448 7.110143e-04 5.791654e-01 7.041170e-01 19 41860778 41860784 7 +      
ENSG00000105372 E009 40309.576939 6.195977e-05 7.761436e-01 8.558578e-01 19 41860785 41860845 61 +      
ENSG00000105372 E010 55933.811490 1.998072e-04 4.954644e-01 6.322561e-01 19 41861112 41861212 101 +      
ENSG00000105372 E011 12.690801 1.146499e-02 8.172290e-03 2.421954e-02 19 41861213 41861225 13 +      
ENSG00000105372 E012 24.337927 2.594250e-02 8.585466e-05 4.556224e-04 19 41861226 41861479 254 +      
ENSG00000105372 E013 23.352618 4.559507e-02 9.050896e-02 1.759317e-01 19 41861480 41861560 81 +      
ENSG00000105372 E014 14.728280 2.813086e-02 1.662605e-06 1.315797e-05 19 41861561 41861606 46 +      
ENSG00000105372 E015 3.387866 1.327801e-01 9.287509e-01 9.591799e-01 19 41863871 41863985 115 +      
ENSG00000105372 E016 81.813240 1.048594e-02 5.485940e-08 5.861126e-07 19 41864174 41864899 726 +      
ENSG00000105372 E017 63671.182896 5.601153e-04 7.699127e-02 1.546708e-01 19 41869031 41869214 184 +      
ENSG00000105372 E018 12.702187 1.413141e-03 3.513459e-02 8.190058e-02 19 41869215 41869223 9 +      
ENSG00000105372 E019 30782.701840 9.383550e-04 5.334741e-01 6.656725e-01 19 41869699 41869753 55 +      
ENSG00000105372 E020 16957.572355 1.001352e-03 6.628746e-01 7.710941e-01 19 41871351 41872925 1575 +