ENSG00000102904

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000415766 ENSG00000102904 HEK293_OSMI2_2hA HEK293_TMG_2hB TSNAXIP1 protein_coding protein_coding 1.704586 1.571927 1.165262 0.121915 0.0785378 -0.4287005 0.10798268 0.1947436 0.1344839 0.03413185 0.10824034 -0.5029096 0.06773750 0.1262667 0.1300333 0.003766667 0.82374994 0.04411416 FALSE TRUE
ENST00000466164 ENSG00000102904 HEK293_OSMI2_2hA HEK293_TMG_2hB TSNAXIP1 protein_coding nonsense_mediated_decay 1.704586 1.571927 1.165262 0.121915 0.0785378 -0.4287005 0.44835615 0.3557643 0.4251898 0.03151488 0.10972469 0.2507304 0.26476667 0.2319333 0.3570333 0.125100000 0.47561985 0.04411416 FALSE TRUE
ENST00000561654 ENSG00000102904 HEK293_OSMI2_2hA HEK293_TMG_2hB TSNAXIP1 protein_coding protein_coding 1.704586 1.571927 1.165262 0.121915 0.0785378 -0.4287005 0.17427536 0.2136627 0.1147305 0.11812703 0.11473046 -0.8425108 0.09314583 0.1261667 0.1136667 -0.012500000 0.73532689 0.04411416   FALSE
ENST00000562321 ENSG00000102904 HEK293_OSMI2_2hA HEK293_TMG_2hB TSNAXIP1 protein_coding processed_transcript 1.704586 1.571927 1.165262 0.121915 0.0785378 -0.4287005 0.09086663 0.0000000 0.0000000 0.00000000 0.00000000 0.0000000 0.05140417 0.0000000 0.0000000 0.000000000   0.04411416   FALSE
ENST00000567852 ENSG00000102904 HEK293_OSMI2_2hA HEK293_TMG_2hB TSNAXIP1 protein_coding protein_coding 1.704586 1.571927 1.165262 0.121915 0.0785378 -0.4287005 0.16162150 0.1507915 0.1888425 0.11281965 0.11213045 0.3064347 0.09130417 0.1091667 0.1512000 0.042033333 0.85867074 0.04411416   FALSE
ENST00000569504 ENSG00000102904 HEK293_OSMI2_2hA HEK293_TMG_2hB TSNAXIP1 protein_coding retained_intron 1.704586 1.571927 1.165262 0.121915 0.0785378 -0.4287005 0.52479495 0.5501614 0.1621729 0.11394614 0.04338993 -1.7019846 0.29104167 0.3434667 0.1355000 -0.207966667 0.04411416 0.04411416 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000102904 E001 0.5138669 0.020659558 0.35392211 0.49819802 16 67806765 67806877 113 + 0.255 0.102 -1.584
ENSG00000102904 E002 0.5138669 0.020659558 0.35392211 0.49819802 16 67806878 67806888 11 + 0.255 0.102 -1.584
ENSG00000102904 E003 0.7353121 0.119828250 0.70588827 0.80416378 16 67806889 67806907 19 + 0.254 0.188 -0.561
ENSG00000102904 E004 4.2612413 0.034482363 0.48518410 0.62310051 16 67806908 67807073 166 + 0.762 0.652 -0.456
ENSG00000102904 E005 2.1714200 0.007080296 0.31071668 0.45314423 16 67807074 67807090 17 + 0.579 0.414 -0.807
ENSG00000102904 E006 1.9897157 0.007615638 0.19929652 0.32535483 16 67807091 67807099 9 + 0.579 0.367 -1.070
ENSG00000102904 E007 2.3197132 0.006687327 0.44229240 0.58393767 16 67807100 67807106 7 + 0.579 0.456 -0.586
ENSG00000102904 E008 1.9510190 0.008133366 0.47603057 0.61472044 16 67807107 67807107 1 + 0.531 0.414 -0.586
ENSG00000102904 E009 2.4272214 0.007114006 0.29432460 0.43543258 16 67807108 67807123 16 + 0.622 0.456 -0.779
ENSG00000102904 E010 2.2475934 0.008376417 0.19689323 0.32234530 16 67807124 67807126 3 + 0.622 0.414 -1.001
ENSG00000102904 E011 2.2475934 0.008376417 0.19689323 0.32234530 16 67807127 67807127 1 + 0.622 0.414 -1.001
ENSG00000102904 E012 3.2450496 0.015046637 0.19269302 0.31714622 16 67807128 67807147 20 + 0.731 0.530 -0.875
ENSG00000102904 E013 4.6997938 0.010505574 0.10834630 0.20309785 16 67807148 67807167 20 + 0.868 0.649 -0.884
ENSG00000102904 E014 4.8093772 0.016784299 0.28591893 0.42628622 16 67807168 67807196 29 + 0.844 0.697 -0.588
ENSG00000102904 E015 1.8339458 0.009188459 0.82322230 0.88859827 16 67807197 67807294 98 + 0.414 0.456 0.221
ENSG00000102904 E016 1.8286484 0.106001336 0.77358051 0.85390621 16 67807295 67807385 91 + 0.476 0.415 -0.313
ENSG00000102904 E017 0.0000000       16 67807668 67807782 115 +      
ENSG00000102904 E018 8.9833121 0.002140213 0.04954577 0.10835668 16 67814302 67814401 100 + 1.099 0.898 -0.743
ENSG00000102904 E019 0.3686942 0.028262501 0.76386166 0.84709715 16 67820839 67820951 113 + 0.146 0.102 -0.583
ENSG00000102904 E020 2.5380630 0.114980976 0.98908120 0.99723502 16 67821099 67821225 127 + 0.531 0.533 0.009
ENSG00000102904 E021 0.3289534 0.029194181 0.76399237   16 67823626 67823719 94 + 0.146 0.102 -0.586
ENSG00000102904 E022 13.0425403 0.020446219 0.15369153 0.26668254 16 67824583 67824779 197 + 1.219 1.066 -0.548
ENSG00000102904 E023 0.1482932 0.041431157 0.70610669   16 67824780 67824783 4 + 0.000 0.102 8.571
ENSG00000102904 E024 13.1267263 0.001521963 0.12512700 0.22732080 16 67825137 67825272 136 + 1.208 1.075 -0.476
ENSG00000102904 E025 0.5138669 0.020659558 0.35392211 0.49819802 16 67825273 67825293 21 + 0.255 0.102 -1.584
ENSG00000102904 E026 11.3227622 0.001670233 0.35593451 0.50030185 16 67825667 67825836 170 + 1.007 1.103 0.350
ENSG00000102904 E027 2.2958644 0.013098077 0.50943315 0.64477511 16 67825837 67825916 80 + 0.414 0.531 0.586
ENSG00000102904 E028 4.6270289 0.052821150 0.34771312 0.49190680 16 67825917 67826027 111 + 0.623 0.796 0.717
ENSG00000102904 E029 5.0612993 0.041718781 0.20610471 0.33381424 16 67826028 67826076 49 + 0.622 0.846 0.915
ENSG00000102904 E030 3.0654179 0.006535260 0.29592269 0.43707007 16 67826077 67826151 75 + 0.476 0.649 0.792
ENSG00000102904 E031 7.1467812 0.004177902 0.45057274 0.59165975 16 67826152 67826282 131 + 0.844 0.939 0.362
ENSG00000102904 E032 9.4363029 0.002006730 0.31747142 0.46035506 16 67826437 67826562 126 + 0.933 1.045 0.413
ENSG00000102904 E033 10.0820131 0.005230603 0.01968733 0.05082520 16 67826692 67826844 153 + 0.844 1.111 0.996
ENSG00000102904 E034 8.7944019 0.041090611 0.14716011 0.25782028 16 67826963 67827072 110 + 0.819 1.043 0.845
ENSG00000102904 E035 8.2615093 0.032393269 0.40177307 0.54546479 16 67827249 67827375 127 + 0.868 0.998 0.489
ENSG00000102904 E036 4.7062583 0.026136339 0.30938561 0.45167243 16 67827473 67827547 75 + 0.622 0.783 0.670
ENSG00000102904 E037 2.6551085 0.043428201 0.99126517 0.99864416 16 67827548 67827549 2 + 0.531 0.534 0.014
ENSG00000102904 E038 3.2461929 0.005306303 0.83806294 0.89875412 16 67827550 67827579 30 + 0.622 0.594 -0.126
ENSG00000102904 E039 5.1657847 0.003341060 0.02110279 0.05381571 16 67827580 67827752 173 + 0.531 0.868 1.413
ENSG00000102904 E040 10.9800938 0.001694170 0.75985123 0.84410240 16 67827753 67827942 190 + 1.040 1.075 0.127
ENSG00000102904 E041 5.0343326 0.076010340 0.63855650 0.75217525 16 67827943 67828068 126 + 0.698 0.810 0.452
ENSG00000102904 E042 0.2955422 0.028591534 0.75983575   16 67831169 67831654 486 + 0.146 0.102 -0.589
ENSG00000102904 E043 0.3289534 0.029194181 0.76399237   16 67832039 67832148 110 + 0.146 0.102 -0.586