ENSG00000102897

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000219168 ENSG00000102897 HEK293_OSMI2_2hA HEK293_TMG_2hB LYRM1 protein_coding protein_coding 11.10263 8.124889 17.96561 1.373888 0.8477836 1.143846 1.48661241 2.1257321 2.1263791 0.17992911 0.28419298 0.0004369276 0.15200000 0.2707667 0.12026667 -0.15050000 1.279828e-02 9.992477e-13 FALSE FALSE
ENST00000439021 ENSG00000102897 HEK293_OSMI2_2hA HEK293_TMG_2hB LYRM1 protein_coding protein_coding 11.10263 8.124889 17.96561 1.373888 0.8477836 1.143846 1.13554176 0.0000000 1.6983691 0.00000000 0.25914371 7.4164759384 0.08501250 0.0000000 0.09393333 0.09393333 9.992477e-13 9.992477e-13 FALSE FALSE
ENST00000562740 ENSG00000102897 HEK293_OSMI2_2hA HEK293_TMG_2hB LYRM1 protein_coding protein_coding 11.10263 8.124889 17.96561 1.373888 0.8477836 1.143846 0.53549127 0.4894967 0.4415958 0.15685966 0.05912589 -0.1454433023 0.05330833 0.0616000 0.02440000 -0.03720000 1.594539e-01 9.992477e-13 TRUE FALSE
ENST00000567954 ENSG00000102897 HEK293_OSMI2_2hA HEK293_TMG_2hB LYRM1 protein_coding protein_coding 11.10263 8.124889 17.96561 1.373888 0.8477836 1.143846 6.70261828 4.3716651 11.8513280 1.25482124 0.86001964 1.4367144259 0.59188750 0.5181000 0.65866667 0.14056667 2.456677e-01 9.992477e-13 FALSE FALSE
ENST00000568663 ENSG00000102897 HEK293_OSMI2_2hA HEK293_TMG_2hB LYRM1 protein_coding protein_coding 11.10263 8.124889 17.96561 1.373888 0.8477836 1.143846 0.07920327 0.5077413 0.0000000 0.05228642 0.00000000 -5.6941595585 0.01073750 0.0672000 0.00000000 -0.06720000 1.058773e-10 9.992477e-13 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000102897 E001 0.0000000       16 20899868 20899901 34 +      
ENSG00000102897 E002 0.6997360 0.0167826625 6.457671e-03 1.981417e-02 16 20899902 20900004 103 + 0.000 0.456 12.013
ENSG00000102897 E003 0.0000000       16 20900129 20900234 106 +      
ENSG00000102897 E004 0.0000000       16 20900235 20900297 63 +      
ENSG00000102897 E005 0.7665583 0.3741425249 2.437445e-02 6.059135e-02 16 20900298 20900410 113 + 0.000 0.463 12.769
ENSG00000102897 E006 2.7594992 0.0082777408 9.670302e-01 9.833285e-01 16 20900411 20900449 39 + 0.573 0.578 0.022
ENSG00000102897 E007 5.6829968 0.0030646833 6.168522e-01 7.348061e-01 16 20900450 20900490 41 + 0.796 0.874 0.306
ENSG00000102897 E008 11.8976748 0.0132618724 4.935321e-02 1.080124e-01 16 20900491 20900535 45 + 1.167 0.948 -0.799
ENSG00000102897 E009 1.2761734 0.2368639098 4.304840e-01 5.731165e-01 16 20900666 20900752 87 + 0.281 0.455 1.023
ENSG00000102897 E010 1.0944690 0.1033879130 6.220162e-01 7.388865e-01 16 20900753 20900758 6 + 0.281 0.378 0.607
ENSG00000102897 E011 1.4234224 0.2041953239 5.725841e-01 6.986671e-01 16 20900759 20900770 12 + 0.330 0.455 0.701
ENSG00000102897 E012 40.9134952 0.0005910287 2.686292e-02 6.570904e-02 16 20900771 20900889 119 + 1.647 1.537 -0.376
ENSG00000102897 E013 2.8678465 0.0056532626 5.222266e-03 1.653590e-02 16 20901104 20901189 86 + 0.375 0.817 2.022
ENSG00000102897 E014 32.4586736 0.0008072704 1.070062e-06 8.825042e-06 16 20902486 20902717 232 + 1.373 1.680 1.052
ENSG00000102897 E015 2.2356054 0.0482644248 2.018077e-02 5.186090e-02 16 20911183 20911264 82 + 0.623 0.165 -2.790
ENSG00000102897 E016 94.0265993 0.0004560495 7.883032e-05 4.224061e-04 16 20915556 20915714 159 + 2.011 1.882 -0.435
ENSG00000102897 E017 81.9952804 0.0003562609 7.948360e-06 5.401560e-05 16 20920122 20920214 93 + 1.962 1.800 -0.544
ENSG00000102897 E018 1.1437748 0.0118153744 7.760803e-01 8.558241e-01 16 20920215 20920606 392 + 0.331 0.285 -0.297
ENSG00000102897 E019 0.2924217 0.0275787873 4.766044e-01   16 20920607 20920674 68 + 0.163 0.000 -12.041
ENSG00000102897 E020 1.6176749 0.4289800592 5.059042e-01 6.416118e-01 16 20921302 20922007 706 + 0.484 0.277 -1.196
ENSG00000102897 E021 333.7711393 0.0013348861 7.218065e-05 3.907755e-04 16 20924000 20925006 1007 + 2.485 2.561 0.254