ENSG00000102882

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000263025 ENSG00000102882 HEK293_OSMI2_2hA HEK293_TMG_2hB MAPK3 protein_coding protein_coding 95.15408 172.8451 63.92548 9.813505 0.232362 -1.434874 62.280420 126.758082 30.431938 2.564493 0.5023752 -2.0580595 0.60349583 0.73700000 0.4760667 -0.26093333 4.481321e-06 3.14751e-09 FALSE TRUE
ENST00000395199 ENSG00000102882 HEK293_OSMI2_2hA HEK293_TMG_2hB MAPK3 protein_coding protein_coding 95.15408 172.8451 63.92548 9.813505 0.232362 -1.434874 9.701943 6.483091 15.457224 3.679045 0.7529420 1.2522368 0.13464583 0.03530000 0.2418667 0.20656667 2.819340e-01 3.14751e-09 FALSE TRUE
ENST00000478356 ENSG00000102882 HEK293_OSMI2_2hA HEK293_TMG_2hB MAPK3 protein_coding protein_coding 95.15408 172.8451 63.92548 9.813505 0.232362 -1.434874 4.559969 5.932971 4.319318 1.183045 1.2507772 -0.4570447 0.05677083 0.03393333 0.0675000 0.03356667 2.685798e-01 3.14751e-09 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000102882 E001 5.8131987 2.897702e-03 8.940199e-02 1.742161e-01 16 30114105 30114105 1 - 0.923 0.696 -0.897
ENSG00000102882 E002 21.2229143 1.479865e-02 9.981043e-01 1.000000e+00 16 30114106 30114119 14 - 1.245 1.253 0.028
ENSG00000102882 E003 247.4604271 3.363898e-03 3.964453e-04 1.760640e-03 16 30114120 30114201 82 - 2.159 2.316 0.523
ENSG00000102882 E004 698.4185146 2.025239e-03 5.993554e-06 4.193494e-05 16 30114202 30114472 271 - 2.626 2.760 0.448
ENSG00000102882 E005 181.6946620 2.045055e-04 6.763590e-02 1.394259e-01 16 30114473 30114545 73 - 2.097 2.166 0.230
ENSG00000102882 E006 294.7873892 7.156190e-03 5.945526e-04 2.513416e-03 16 30114546 30114615 70 - 2.212 2.393 0.605
ENSG00000102882 E007 595.1927891 6.380961e-03 3.133154e-04 1.433909e-03 16 30114616 30114708 93 - 2.530 2.695 0.547
ENSG00000102882 E008 31.6307022 1.708976e-02 4.204021e-01 5.636114e-01 16 30115595 30115645 51 - 1.457 1.389 -0.235
ENSG00000102882 E009 0.9514719 4.368767e-02 9.472489e-01 9.708479e-01 16 30115646 30115999 354 - 0.208 0.229 0.176
ENSG00000102882 E010 2.7553134 2.954474e-01 6.346263e-01 7.490470e-01 16 30116635 30116635 1 - 0.347 0.510 0.867
ENSG00000102882 E011 566.3305322 3.424904e-03 2.719962e-03 9.432339e-03 16 30116636 30116667 32 - 2.554 2.666 0.371
ENSG00000102882 E012 511.7390857 1.733654e-03 2.698102e-04 1.256909e-03 16 30116668 30116688 21 - 2.508 2.622 0.377
ENSG00000102882 E013 1001.2843059 8.979952e-05 8.912161e-07 7.480316e-06 16 30116689 30116786 98 - 2.827 2.906 0.262
ENSG00000102882 E014 556.6326319 7.470131e-04 4.346313e-02 9.740182e-02 16 30116787 30116790 4 - 2.595 2.649 0.180
ENSG00000102882 E015 1.8360327 8.219949e-03 5.360619e-02 1.155653e-01 16 30116791 30116836 46 - 0.000 0.435 11.671
ENSG00000102882 E016 0.2214452 3.843606e-02 1.000000e+00   16 30116837 30116893 57 - 0.000 0.069 7.717
ENSG00000102882 E017 884.8814535 3.749835e-04 3.853431e-01 5.295370e-01 16 30116894 30116949 56 - 2.821 2.844 0.075
ENSG00000102882 E018 597.6575505 2.702670e-04 5.284122e-01 6.613338e-01 16 30116950 30116950 1 - 2.673 2.668 -0.016
ENSG00000102882 E019 1044.3920756 7.765145e-05 7.606228e-01 8.446505e-01 16 30116951 30117003 53 - 2.908 2.911 0.010
ENSG00000102882 E020 6.9070608 1.149610e-02 1.329769e-01 2.382500e-01 16 30117004 30117105 102 - 0.954 0.753 -0.777
ENSG00000102882 E021 2.8784411 5.311347e-03 8.509336e-01 9.075759e-01 16 30117137 30117153 17 - 0.539 0.510 -0.135
ENSG00000102882 E022 1355.0003899 1.384428e-04 5.306983e-01 6.632445e-01 16 30117154 30117285 132 - 3.024 3.024 -0.002
ENSG00000102882 E023 3.4709610 4.027852e-02 3.669818e-02 8.490292e-02 16 30117286 30117286 1 - 0.815 0.465 -1.531
ENSG00000102882 E024 1266.3716896 1.475619e-04 3.614195e-02 8.386494e-02 16 30117670 30117784 115 - 3.009 2.990 -0.066
ENSG00000102882 E025 9.4084043 1.768845e-03 1.736201e-02 4.573961e-02 16 30117898 30118046 149 - 1.124 0.857 -0.987
ENSG00000102882 E026 811.7472387 3.731155e-04 8.791414e-03 2.576230e-02 16 30118047 30118098 52 - 2.831 2.793 -0.125
ENSG00000102882 E027 534.6508295 5.788179e-04 1.951390e-03 7.075851e-03 16 30118099 30118102 4 - 2.666 2.607 -0.195
ENSG00000102882 E028 844.5291746 4.193291e-04 3.888146e-04 1.731460e-03 16 30118103 30118163 61 - 2.861 2.807 -0.177
ENSG00000102882 E029 1354.1503596 4.873457e-04 1.427316e-06 1.146495e-05 16 30118349 30118538 190 - 3.074 3.010 -0.211
ENSG00000102882 E030 1068.3366039 5.146491e-04 1.696099e-07 1.648560e-06 16 30121824 30122006 183 - 2.982 2.905 -0.256
ENSG00000102882 E031 5.5710383 4.514721e-03 7.207181e-01 8.152878e-01 16 30122007 30122039 33 - 0.772 0.725 -0.192
ENSG00000102882 E032 10.7529183 4.865112e-03 1.485162e-07 1.459183e-06 16 30122040 30122926 887 - 1.353 0.813 -1.967
ENSG00000102882 E033 6.3347432 4.473978e-03 1.365082e-03 5.193039e-03 16 30122927 30122990 64 - 1.059 0.649 -1.598
ENSG00000102882 E034 489.3579124 1.122751e-03 2.051732e-05 1.269497e-04 16 30123040 30123309 270 - 2.658 2.561 -0.321
ENSG00000102882 E035 0.0000000       16 30123476 30123506 31 -