ENSG00000102879

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000219150 ENSG00000102879 HEK293_OSMI2_2hA HEK293_TMG_2hB CORO1A protein_coding protein_coding 6.650593 12.18626 2.826694 0.8631854 0.05555643 -2.104156 5.6498549 10.7445 2.2887028 0.7748056 0.1982171 -2.226049 0.80020000 0.8842667 0.8085667 -0.0757000 5.983724e-01 2.958485e-07 FALSE TRUE
ENST00000568982 ENSG00000102879 HEK293_OSMI2_2hA HEK293_TMG_2hB CORO1A protein_coding retained_intron 6.650593 12.18626 2.826694 0.8631854 0.05555643 -2.104156 0.1439725 0.0000 0.3233238 0.0000000 0.1114775 5.058852 0.04297917 0.0000000 0.1153333 0.1153333 2.958485e-07 2.958485e-07 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000102879 E001 0.0000000       16 30182774 30182826 53 +      
ENSG00000102879 E002 1.1080969 0.1074600167 0.9082370314 0.945711983 16 30182827 30182986 160 + 0.237 0.270 0.247
ENSG00000102879 E003 1.4715057 0.1647711158 0.7085344299 0.806174834 16 30182987 30183013 27 + 0.237 0.331 0.657
ENSG00000102879 E004 0.5117019 0.0346914780 0.7918442297 0.866853778 16 30183014 30183133 120 + 0.000 0.158 12.189
ENSG00000102879 E005 0.9578015 0.1115870226 0.8416197055 0.901201254 16 30183514 30183601 88 + 0.237 0.202 -0.286
ENSG00000102879 E006 0.9578015 0.1115870226 0.8416197055 0.901201254 16 30183602 30183604 3 + 0.237 0.202 -0.286
ENSG00000102879 E007 0.9578015 0.1115870226 0.8416197055 0.901201254 16 30183605 30183608 4 + 0.237 0.202 -0.286
ENSG00000102879 E008 2.0543574 0.0083989134 0.4660171726 0.605595682 16 30183609 30183616 8 + 0.237 0.392 1.015
ENSG00000102879 E009 2.4919518 0.0135476098 0.2842923351 0.424522575 16 30183617 30183618 2 + 0.591 0.392 -0.983
ENSG00000102879 E010 6.4924814 0.0088040415 0.4099062799 0.553531695 16 30183619 30183619 1 + 0.832 0.708 -0.497
ENSG00000102879 E011 9.7762345 0.0146268756 0.7386336147 0.828465246 16 30183620 30183620 1 + 0.916 0.874 -0.161
ENSG00000102879 E012 21.4920463 0.0009043652 0.9426429600 0.967981011 16 30183621 30183633 13 + 1.190 1.198 0.027
ENSG00000102879 E013 50.6351730 0.0005308443 0.4840831603 0.622104130 16 30183634 30183725 92 + 1.517 1.564 0.162
ENSG00000102879 E014 0.2214452 0.0370526383 1.0000000000   16 30183825 30183961 137 + 0.000 0.059 10.681
ENSG00000102879 E015 0.0000000       16 30184218 30184225 8 +      
ENSG00000102879 E016 0.1472490 0.0427495699 0.0805179189   16 30184226 30184343 118 + 0.237 0.000 -14.590
ENSG00000102879 E017 0.2944980 0.2888056839 0.0276469114   16 30184352 30184421 70 + 0.389 0.000 -14.726
ENSG00000102879 E018 1.0800860 0.1069410096 0.0279179716 0.067850878 16 30184748 30184964 217 + 0.592 0.157 -2.743
ENSG00000102879 E019 85.2066437 0.0003612747 0.8329935887 0.895375473 16 30185209 30185407 199 + 1.786 1.777 -0.033
ENSG00000102879 E020 2.9431636 0.0053860941 0.0065999185 0.020185899 16 30185408 30185857 450 + 0.832 0.391 -1.988
ENSG00000102879 E021 1.4726239 0.0095364638 0.1783107717 0.299023987 16 30185858 30185931 74 + 0.000 0.336 13.532
ENSG00000102879 E022 4.2394940 0.0040594697 0.1352872658 0.241519112 16 30185932 30186413 482 + 0.783 0.542 -1.028
ENSG00000102879 E023 2.5046242 0.0063242937 0.2761449044 0.415556503 16 30186414 30186597 184 + 0.591 0.392 -0.986
ENSG00000102879 E024 53.5495009 0.0039877518 0.8475832408 0.905345637 16 30186598 30186681 84 + 1.562 1.580 0.061
ENSG00000102879 E025 32.3946001 0.0096040933 0.3162144273 0.458967957 16 30186682 30186720 39 + 1.433 1.351 -0.282
ENSG00000102879 E026 0.5911836 0.0224105357 0.7944205666 0.868660208 16 30186721 30186815 95 + 0.000 0.158 12.233
ENSG00000102879 E027 57.5355396 0.0004688838 0.1718704021 0.290647184 16 30186816 30186945 130 + 1.676 1.596 -0.270
ENSG00000102879 E028 1.3704314 0.0105318548 0.0009931835 0.003934993 16 30186946 30187038 93 + 0.728 0.158 -3.312
ENSG00000102879 E029 75.3430118 0.0003913479 0.5160035022 0.650610217 16 30187039 30187223 185 + 1.754 1.721 -0.113
ENSG00000102879 E030 55.6092195 0.0006076672 0.2093005357 0.337694038 16 30187382 30187501 120 + 1.526 1.609 0.281
ENSG00000102879 E031 0.0000000       16 30187502 30187724 223 +      
ENSG00000102879 E032 53.4240641 0.0005047382 0.6219288929 0.738812805 16 30187725 30187829 105 + 1.554 1.586 0.111
ENSG00000102879 E033 0.3299976 0.0274424043 1.0000000000   16 30187830 30187941 112 + 0.000 0.111 11.668
ENSG00000102879 E034 59.3981715 0.0004790121 0.5101919902 0.645429390 16 30187942 30188074 133 + 1.588 1.629 0.140
ENSG00000102879 E035 36.0022880 0.0005918247 0.8812452977 0.927887763 16 30188075 30188087 13 + 1.421 1.410 -0.038
ENSG00000102879 E036 0.3697384 0.0274424043 1.0000000000 1.000000000 16 30188088 30188191 104 + 0.000 0.111 11.669
ENSG00000102879 E037 50.4908678 0.0005352125 0.7116604665 0.808590417 16 30188192 30188249 58 + 1.536 1.561 0.086
ENSG00000102879 E038 0.8010032 0.1602844793 0.0519731007 0.112681941 16 30188250 30188360 111 + 0.501 0.112 -2.887
ENSG00000102879 E039 81.6258046 0.0006546957 0.1544977305 0.267752818 16 30188361 30188576 216 + 1.695 1.772 0.261
ENSG00000102879 E040 0.3299976 0.0274424043 1.0000000000   16 30188577 30188859 283 + 0.000 0.111 11.668
ENSG00000102879 E041 32.1000080 0.0434567135 0.1604164587 0.275691488 16 30188860 30189076 217 + 1.210 1.389 0.626