ENSG00000102103

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000247140 ENSG00000102103 HEK293_OSMI2_2hA HEK293_TMG_2hB PQBP1 protein_coding protein_coding 141.74 245.2623 96.19572 10.61187 1.819487 -1.35019 13.895999 27.18965 9.426608 1.438984 1.6749290 -1.527248 0.0942250 0.11140000 0.09753333 -0.01386667 0.7687036168 3.787315e-27 FALSE  
ENST00000376563 ENSG00000102103 HEK293_OSMI2_2hA HEK293_TMG_2hB PQBP1 protein_coding protein_coding 141.74 245.2623 96.19572 10.61187 1.819487 -1.35019 20.298789 42.46476 8.401754 4.286471 0.6270165 -2.336127 0.1286542 0.17263333 0.08766667 -0.08496667 0.0001209061 3.787315e-27 FALSE  
ENST00000447146 ENSG00000102103 HEK293_OSMI2_2hA HEK293_TMG_2hB PQBP1 protein_coding protein_coding 141.74 245.2623 96.19572 10.61187 1.819487 -1.35019 74.716841 124.31578 53.458576 6.105015 1.5576619 -1.217362 0.5337750 0.50666667 0.55553333 0.04886667 0.0541986223 3.787315e-27 FALSE  
MSTRG.34222.14 ENSG00000102103 HEK293_OSMI2_2hA HEK293_TMG_2hB PQBP1 protein_coding   141.74 245.2623 96.19572 10.61187 1.819487 -1.35019 9.518921 16.25422 6.910301 1.900043 0.5533254 -1.232795 0.0705375 0.06623333 0.07193333 0.00570000 0.8526223999 3.787315e-27 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000102103 E001 0.000000       X 48890197 48890697 501 +      
ENSG00000102103 E002 14.593758 0.0011910081 1.399698e-01 2.479834e-01 X 48897481 48897911 431 + 1.225 1.089 -0.486
ENSG00000102103 E003 16.571642 0.0011157637 2.532464e-01 3.897382e-01 X 48897912 48897925 14 + 1.252 1.153 -0.352
ENSG00000102103 E004 19.759546 0.0009364267 9.825067e-02 1.878651e-01 X 48897926 48897929 4 + 1.347 1.214 -0.467
ENSG00000102103 E005 20.712995 0.0010708909 5.959313e-02 1.259299e-01 X 48897930 48897930 1 + 1.378 1.229 -0.521
ENSG00000102103 E006 41.100945 0.0005455274 1.113646e-01 2.075543e-01 X 48897931 48897937 7 + 1.622 1.530 -0.314
ENSG00000102103 E007 53.672060 0.0006049379 1.919731e-03 6.976679e-03 X 48897938 48897939 2 + 1.781 1.622 -0.539
ENSG00000102103 E008 56.183870 0.0007875217 3.694679e-03 1.228075e-02 X 48897940 48897941 2 + 1.792 1.645 -0.498
ENSG00000102103 E009 65.650781 0.0003979455 2.051705e-04 9.861458e-04 X 48897942 48897942 1 + 1.875 1.704 -0.578
ENSG00000102103 E010 70.730091 0.0003885372 1.616740e-05 1.024267e-04 X 48897943 48897943 1 + 1.920 1.728 -0.647
ENSG00000102103 E011 160.196179 0.0003636866 6.493342e-12 1.393457e-10 X 48897944 48897946 3 + 2.284 2.075 -0.698
ENSG00000102103 E012 310.543117 0.0020782316 1.555146e-06 1.238593e-05 X 48897947 48897951 5 + 2.528 2.380 -0.494
ENSG00000102103 E013 904.294877 0.0001047789 1.986988e-02 5.121622e-02 X 48897952 48897995 44 + 2.855 2.892 0.124
ENSG00000102103 E014 1026.929086 0.0001163595 1.016169e-02 2.916291e-02 X 48897996 48898014 19 + 2.909 2.947 0.129
ENSG00000102103 E015 677.986924 0.0004621949 1.917659e-01 3.159744e-01 X 48898015 48898040 26 + 2.737 2.765 0.092
ENSG00000102103 E016 592.715514 0.0008808174 1.086900e-01 2.035970e-01 X 48898041 48898082 42 + 2.724 2.693 -0.104
ENSG00000102103 E017 78.364551 0.0004084844 9.132834e-02 1.772044e-01 X 48898083 48898084 2 + 1.882 1.810 -0.241
ENSG00000102103 E018 84.389466 0.0017407041 1.994878e-01 3.255969e-01 X 48898085 48898093 9 + 1.903 1.846 -0.192
ENSG00000102103 E019 7.000496 0.0557607716 9.388826e-05 4.932160e-04 X 48898094 48898108 15 + 1.212 0.597 -2.372
ENSG00000102103 E020 28.043361 0.0055640217 8.899746e-09 1.107409e-07 X 48898109 48898259 151 + 1.675 1.253 -1.455
ENSG00000102103 E021 64.011637 0.0048726933 1.613288e-01 2.768176e-01 X 48898260 48898317 58 + 1.800 1.721 -0.269
ENSG00000102103 E022 65.840026 0.0014305565 4.136156e-01 5.570715e-01 X 48898318 48898346 29 + 1.781 1.742 -0.130
ENSG00000102103 E023 48.509431 0.0069809513 8.902410e-02 1.736386e-01 X 48898347 48898350 4 + 1.704 1.589 -0.390
ENSG00000102103 E024 48.908443 0.0042787064 2.468116e-05 1.499558e-04 X 48898351 48898491 141 + 1.807 1.554 -0.861
ENSG00000102103 E025 921.595889 0.0006586482 8.811482e-01 9.278113e-01 X 48898492 48898509 18 + 2.887 2.892 0.015
ENSG00000102103 E026 1369.968246 0.0013033773 2.909391e-01 4.317527e-01 X 48898510 48898576 67 + 3.045 3.066 0.069
ENSG00000102103 E027 1749.444787 0.0006075181 8.101634e-01 8.795116e-01 X 48901190 48901301 112 + 3.170 3.168 -0.007
ENSG00000102103 E028 13.864111 0.0015394245 5.309812e-12 1.155973e-10 X 48901302 48901311 10 + 1.483 0.870 -2.196
ENSG00000102103 E029 28.982256 0.0060663921 1.138623e-15 4.267233e-14 X 48901312 48901518 207 + 1.769 1.183 -2.021
ENSG00000102103 E030 55.451916 0.0004314218 3.518543e-12 7.894096e-11 X 48901519 48901929 411 + 1.912 1.575 -1.140
ENSG00000102103 E031 1852.847348 0.0005382710 7.398513e-01 8.294529e-01 X 48901930 48902042 113 + 3.195 3.193 -0.006
ENSG00000102103 E032 25.074477 0.0068330034 2.657883e-04 1.240247e-03 X 48902043 48902218 176 + 1.548 1.258 -1.005
ENSG00000102103 E033 15.517899 0.0349382673 2.300158e-01 3.624716e-01 X 48902219 48902232 14 + 1.253 1.105 -0.527
ENSG00000102103 E034 1831.892953 0.0006003609 2.381770e-01 3.720259e-01 X 48902233 48902384 152 + 3.199 3.186 -0.045
ENSG00000102103 E035 1600.737318 0.0005976130 1.911843e-01 3.152135e-01 X 48902385 48902517 133 + 3.113 3.135 0.075
ENSG00000102103 E036 79.025623 0.0006543284 1.379361e-13 3.843443e-12 X 48902518 48902731 214 + 2.047 1.738 -1.043
ENSG00000102103 E037 645.611505 0.0004879710 3.858616e-05 2.232480e-04 X 48902732 48902734 3 + 2.670 2.754 0.279
ENSG00000102103 E038 1173.150969 0.0003883795 1.986876e-08 2.318209e-07 X 48902735 48902795 61 + 2.926 3.015 0.296
ENSG00000102103 E039 21.490119 0.0011717360 1.901177e-04 9.216988e-04 X 48902796 48902927 132 + 1.483 1.198 -0.992
ENSG00000102103 E040 1264.831017 0.0004484495 3.668850e-08 4.059887e-07 X 48902928 48903402 475 + 2.960 3.048 0.291