ENSG00000102038

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000371121 ENSG00000102038 HEK293_OSMI2_2hA HEK293_TMG_2hB SMARCA1 protein_coding protein_coding 10.84153 6.712677 19.90317 0.07930705 0.2855459 1.566615 3.0476946 0.0000000 7.0903625 0.0000000 2.332424 9.47174886 0.20141667 0.0000 0.3576333 0.35763333 9.267674e-07 9.267674e-07 FALSE TRUE
ENST00000371122 ENSG00000102038 HEK293_OSMI2_2hA HEK293_TMG_2hB SMARCA1 protein_coding protein_coding 10.84153 6.712677 19.90317 0.07930705 0.2855459 1.566615 0.6495934 0.8327282 0.7788098 0.0395742 0.339462 -0.09538981 0.07438333 0.1242 0.0394000 -0.08480000 1.659680e-01 9.267674e-07 FALSE TRUE
ENST00000371123 ENSG00000102038 HEK293_OSMI2_2hA HEK293_TMG_2hB SMARCA1 protein_coding protein_coding 10.84153 6.712677 19.90317 0.07930705 0.2855459 1.566615 2.9082647 4.4140669 5.2161794 0.3134139 2.263007 0.24038343 0.31369167 0.6574 0.2605000 -0.39690000 2.400521e-02 9.267674e-07 FALSE TRUE
MSTRG.34844.3 ENSG00000102038 HEK293_OSMI2_2hA HEK293_TMG_2hB SMARCA1 protein_coding   10.84153 6.712677 19.90317 0.07930705 0.2855459 1.566615 0.6948631 0.0000000 0.0000000 0.0000000 0.000000 0.00000000 0.10517917 0.0000 0.0000000 0.00000000   9.267674e-07 FALSE TRUE
MSTRG.34844.7 ENSG00000102038 HEK293_OSMI2_2hA HEK293_TMG_2hB SMARCA1 protein_coding   10.84153 6.712677 19.90317 0.07930705 0.2855459 1.566615 1.1307792 1.4354058 2.6296392 0.2987475 2.629639 0.86886617 0.13835833 0.2139 0.1306667 -0.08323333 1.858348e-01 9.267674e-07 FALSE TRUE
MSTRG.34844.8 ENSG00000102038 HEK293_OSMI2_2hA HEK293_TMG_2hB SMARCA1 protein_coding   10.84153 6.712677 19.90317 0.07930705 0.2855459 1.566615 2.3230129 0.0000000 4.0639141 0.0000000 2.032178 8.67027174 0.15764583 0.0000 0.2054333 0.20543333 2.699120e-01 9.267674e-07 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000102038 E001 0.1482932 0.0414089468 1.825384e-01   X 129446501 129446504 4 - 0.000 0.192 12.133
ENSG00000102038 E002 0.1482932 0.0414089468 1.825384e-01   X 129446505 129446505 1 - 0.000 0.192 12.158
ENSG00000102038 E003 45.2601455 0.0504901870 4.138138e-05 2.376926e-04 X 129446506 129446753 248 - 1.372 1.948 1.962
ENSG00000102038 E004 77.4318294 0.0397336123 7.388465e-07 6.315298e-06 X 129446754 129446846 93 - 1.593 2.179 1.974
ENSG00000102038 E005 205.4149185 0.0109449989 2.340099e-13 6.317236e-12 X 129446847 129447233 387 - 2.091 2.540 1.497
ENSG00000102038 E006 25.6253174 0.0007850944 7.116371e-05 3.857991e-04 X 129447234 129447301 68 - 1.259 1.583 1.119
ENSG00000102038 E007 7.7392775 0.0681194919 3.018941e-02 7.234026e-02 X 129448302 129448332 31 - 0.745 1.153 1.534
ENSG00000102038 E008 114.9932732 0.0018641766 3.058338e-05 1.815823e-04 X 129448333 129448443 111 - 1.952 2.162 0.704
ENSG00000102038 E009 160.5759685 0.0002263077 2.419409e-04 1.141433e-03 X 129465520 129465732 213 - 2.117 2.272 0.518
ENSG00000102038 E010 137.7992710 0.0002295733 7.555133e-01 8.408317e-01 X 129465844 129465962 119 - 2.083 2.141 0.193
ENSG00000102038 E011 132.9606920 0.0002815354 1.722559e-01 2.911417e-01 X 129468773 129468905 133 - 2.057 2.149 0.309
ENSG00000102038 E012 105.8200683 0.0002889804 3.526819e-01 4.969211e-01 X 129471204 129471326 123 - 1.962 2.043 0.274
ENSG00000102038 E013 100.0932263 0.0002926700 4.840010e-01 6.220323e-01 X 129480701 129480814 114 - 1.957 1.977 0.068
ENSG00000102038 E014 0.5117906 0.2305487321 7.957997e-01 8.696061e-01 X 129480815 129481074 260 - 0.140 0.194 0.570
ENSG00000102038 E015 99.0219391 0.0003146403 6.046231e-01 7.250907e-01 X 129481075 129481185 111 - 1.937 2.004 0.225
ENSG00000102038 E016 104.7942124 0.0010461048 8.669100e-01 9.183470e-01 X 129487018 129487137 120 - 1.971 2.012 0.135
ENSG00000102038 E017 130.4920124 0.0002587030 4.858363e-01 6.236633e-01 X 129488937 129489085 149 - 2.071 2.095 0.081
ENSG00000102038 E018 109.4532500 0.0005023468 8.259966e-02 1.636125e-01 X 129490060 129490192 133 - 2.006 1.988 -0.063
ENSG00000102038 E019 107.2826950 0.0029122239 5.806710e-03 1.810477e-02 X 129491941 129492093 153 - 2.014 1.933 -0.270
ENSG00000102038 E020 29.9203598 0.0006812768 1.389060e-04 6.987979e-04 X 129493040 129493075 36 - 1.506 1.261 -0.850
ENSG00000102038 E021 99.4884081 0.0015724726 9.806977e-05 5.129493e-04 X 129496750 129496871 122 - 1.992 1.866 -0.426
ENSG00000102038 E022 128.3458352 0.0002684259 5.587664e-06 3.934021e-05 X 129497845 129498071 227 - 2.102 1.987 -0.384
ENSG00000102038 E023 81.8241035 0.0018107690 1.812129e-03 6.637710e-03 X 129499732 129499841 110 - 1.906 1.801 -0.352
ENSG00000102038 E024 59.7659255 0.0036335187 6.735254e-03 2.053617e-02 X 129504734 129504802 69 - 1.773 1.658 -0.390
ENSG00000102038 E025 81.1709248 0.0250354879 1.069121e-01 2.009801e-01 X 129506080 129506211 132 - 1.897 1.804 -0.313
ENSG00000102038 E026 78.2803638 0.0062603011 6.980872e-03 2.117397e-02 X 129507941 129508054 114 - 1.887 1.772 -0.389
ENSG00000102038 E027 59.3011412 0.0003795171 2.185825e-02 5.538366e-02 X 129508055 129508096 42 - 1.759 1.688 -0.239
ENSG00000102038 E028 114.9063832 0.0002801098 8.871649e-11 1.579555e-09 X 129511804 129511983 180 - 2.074 1.868 -0.692
ENSG00000102038 E029 82.2588767 0.0003384757 5.413125e-08 5.791198e-07 X 129515687 129515787 101 - 1.930 1.726 -0.686
ENSG00000102038 E030 78.5940957 0.0003902970 2.040763e-07 1.952214e-06 X 129515894 129515994 101 - 1.910 1.712 -0.666
ENSG00000102038 E031 90.9200773 0.0028086348 1.148058e-07 1.153459e-06 X 129516331 129516497 167 - 1.977 1.753 -0.753
ENSG00000102038 E032 53.4237278 0.0005502269 2.326711e-07 2.202951e-06 X 129518361 129518447 87 - 1.755 1.499 -0.869
ENSG00000102038 E033 65.6879966 0.0004641947 2.821905e-08 3.193366e-07 X 129523197 129523451 255 - 1.840 1.595 -0.831
ENSG00000102038 E034 16.8763432 0.0010334089 1.127228e-02 3.181236e-02 X 129523452 129523508 57 - 1.263 1.063 -0.716
ENSG00000102038 E035 0.1472490 0.0437992989 1.000000e+00   X 129523638 129523692 55 - 0.076 0.000 -9.349
ENSG00000102038 E036 0.0000000       X 129523830 129523862 33 -