ENSG00000101928

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000370779 ENSG00000101928 HEK293_OSMI2_2hA HEK293_TMG_2hB MOSPD1 protein_coding protein_coding 16.12376 6.488117 32.00321 0.8805928 1.154662 2.300574 4.3039982 0.7516195 9.440282 0.39911733 1.4828005 3.633215 0.19807917 0.11420000 0.29243333 0.17823333 0.4078877350 0.0001705497 FALSE TRUE
ENST00000370783 ENSG00000101928 HEK293_OSMI2_2hA HEK293_TMG_2hB MOSPD1 protein_coding protein_coding 16.12376 6.488117 32.00321 0.8805928 1.154662 2.300574 8.8304223 4.8344145 16.365075 0.85062810 0.5530121 1.757107 0.61389167 0.73843333 0.51186667 -0.22656667 0.0001705497 0.0001705497 FALSE TRUE
MSTRG.34917.2 ENSG00000101928 HEK293_OSMI2_2hA HEK293_TMG_2hB MOSPD1 protein_coding   16.12376 6.488117 32.00321 0.8805928 1.154662 2.300574 0.8973973 0.4689585 1.879022 0.09347483 0.1168510 1.979667 0.06880833 0.07836667 0.05906667 -0.01930000 0.8505167253 0.0001705497 FALSE TRUE
MSTRG.34917.8 ENSG00000101928 HEK293_OSMI2_2hA HEK293_TMG_2hB MOSPD1 protein_coding   16.12376 6.488117 32.00321 0.8805928 1.154662 2.300574 1.4581075 0.3117834 2.709425 0.23782257 0.8227361 3.079140 0.07472500 0.05426667 0.08603333 0.03176667 0.5899803156 0.0001705497 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000101928 E001 395.2315473 0.0087092017 5.823890e-05 0.0003227871 X 134887632 134888934 1303 - 2.470 2.670 0.664
ENSG00000101928 E002 30.3195479 0.0007019808 1.815751e-01 0.3032125396 X 134888935 134888953 19 - 1.385 1.537 0.522
ENSG00000101928 E003 29.0377338 0.0059609583 1.084521e-01 0.2032558849 X 134888954 134888998 45 - 1.358 1.537 0.616
ENSG00000101928 E004 16.0794686 0.0242399457 1.836874e-01 0.3058295431 X 134888999 134889014 16 - 1.106 1.303 0.698
ENSG00000101928 E005 13.7703750 0.0129159772 1.685334e-01 0.2862509972 X 134889015 134889016 2 - 1.042 1.242 0.715
ENSG00000101928 E006 46.5794334 0.0004868729 8.998354e-02 0.1751133741 X 134889017 134889122 106 - 1.614 1.569 -0.153
ENSG00000101928 E007 61.5378188 0.0003971270 2.291099e-03 0.0081224980 X 134889123 134889192 70 - 1.747 1.639 -0.363
ENSG00000101928 E008 57.1814621 0.0004215662 2.175803e-01 0.3474780683 X 134891479 134891640 162 - 1.696 1.689 -0.024
ENSG00000101928 E009 0.7675920 0.0155830542 3.730733e-01 0.5175090319 X 134893216 134893249 34 - 0.172 0.364 1.434
ENSG00000101928 E010 4.6723918 0.0518389318 8.449373e-01 0.9035332015 X 134896814 134896816 3 - 0.674 0.747 0.301
ENSG00000101928 E011 98.6668814 0.0003156379 8.702695e-02 0.1706374863 X 134896817 134896888 72 - 1.929 1.918 -0.035
ENSG00000101928 E012 132.6545009 0.0002660688 7.056241e-04 0.0029191241 X 134896889 134897034 146 - 2.067 2.005 -0.207
ENSG00000101928 E013 1.5113377 0.0089461409 5.685461e-01 0.6951950853 X 134899018 134899089 72 - 0.329 0.472 0.796
ENSG00000101928 E014 102.2325938 0.0003401868 1.011837e-03 0.0039994454 X 134899090 134899165 76 - 1.959 1.883 -0.257
ENSG00000101928 E015 1.0499988 0.1524880798 1.813700e-01 0.3029661479 X 134899166 134899279 114 - 0.329 0.000 -10.503
ENSG00000101928 E016 158.5334143 0.0003315596 7.295755e-05 0.0003943955 X 134899280 134899534 255 - 2.145 2.073 -0.240
ENSG00000101928 E017 0.7268175 1.0285014077 1.133291e-01 0.2103715668 X 134899831 134899952 122 - 0.000 0.564 13.442
ENSG00000101928 E018 6.7256840 0.0024481033 8.545420e-01 0.9100233386 X 134904737 134904858 122 - 0.802 0.878 0.297
ENSG00000101928 E019 52.0841619 0.0020270825 4.187074e-02 0.0944837179 X 134915182 134915257 76 - 1.666 1.598 -0.232