ENSG00000101849

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-5 / 5
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000407597	ENSG00000101849	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TBL1X	protein_coding	protein_coding	19.79436	22.81654	19.49237	1.713333	0.4996396	-0.2270629	2.1770705	1.190179	4.439498	0.6430834	0.4445985	1.89039266	0.1116333	0.04883333	0.22903333	0.18020000	0.003141249	0.003141249	FALSE	TRUE
ENST00000424279	ENSG00000101849	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TBL1X	protein_coding	protein_coding	19.79436	22.81654	19.49237	1.713333	0.4996396	-0.2270629	2.7994010	4.467110	1.620229	1.1931388	0.9675673	-1.45749311	0.1364333	0.19413333	0.08190000	-0.11223333	0.577009289	0.003141249	FALSE	TRUE
ENST00000683056	ENSG00000101849	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TBL1X	protein_coding	protein_coding	19.79436	22.81654	19.49237	1.713333	0.4996396	-0.2270629	0.3266022	1.928125	0.000000	1.4067169	0.0000000	-7.59851756	0.0150500	0.08800000	0.00000000	-0.08800000	0.204455476	0.003141249	FALSE	TRUE
MSTRG.33886.5	ENSG00000101849	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TBL1X	protein_coding		19.79436	22.81654	19.49237	1.713333	0.4996396	-0.2270629	9.0224232	9.790356	9.441110	2.9350906	1.0043522	-0.05235039	0.4569292	0.42320000	0.48696667	0.06376667	0.843036006	0.003141249	FALSE	TRUE
MSTRG.33886.8	ENSG00000101849	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TBL1X	protein_coding		19.79436	22.81654	19.49237	1.713333	0.4996396	-0.2270629	3.5847237	4.470893	1.710541	0.8947182	0.8560477	-1.38092392	0.1834542	0.20396667	0.08576667	-0.11820000	0.620363582	0.003141249	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

No results under this category.

All exons whithin this gene region are shown and numbering below.

No results under this category.

All isoforms whithin this gene region are shown below.

No results under this category.

Rows: 1-10 / 43
Columns:
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groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000101849	E001	2.5754910	0.1369042591	1.210646e-01	2.214604e-01	X	9463320	9463328	9	+	0.656	0.442	-0.998
ENSG00000101849	E002	3.8654958	0.0039542913	2.916270e-02	7.031406e-02	X	9463329	9463330	2	+	0.779	0.588	-0.801
ENSG00000101849	E003	14.0679194	0.0013130590	6.361359e-06	4.424319e-05	X	9463331	9463462	132	+	1.291	1.030	-0.935
ENSG00000101849	E004	6.4454908	0.0044993242	4.235070e-02	9.536345e-02	X	9465058	9465293	236	+	0.922	0.806	-0.449
ENSG00000101849	E005	26.0396336	0.0253530742	9.276235e-03	2.697564e-02	X	9465294	9465447	154	+	1.479	1.367	-0.387
ENSG00000101849	E006	0.8803962	0.0144061202	2.291050e-01	3.613595e-01	X	9466196	9466426	231	+	0.112	0.387	2.288
ENSG00000101849	E007	0.6986918	0.0167907076	3.912141e-01	5.351409e-01	X	9466427	9466457	31	+	0.112	0.318	1.873
ENSG00000101849	E008	1.7327815	0.1334194418	8.570475e-01	9.116768e-01	X	9481612	9481638	27	+	0.394	0.452	0.315
ENSG00000101849	E009	0.0000000				X	9491366	9491513	148	+
ENSG00000101849	E010	53.4134189	0.0142277691	2.904544e-04	1.341011e-03	X	9501780	9501849	70	+	1.790	1.669	-0.408
ENSG00000101849	E011	0.0000000				X	9530983	9531005	23	+
ENSG00000101849	E012	0.0000000				X	9531006	9531038	33	+
ENSG00000101849	E013	0.0000000				X	9531039	9531088	50	+
ENSG00000101849	E014	0.8157519	0.0167528129	5.383202e-01	6.697565e-01	X	9534900	9534942	43	+	0.275	0.235	-0.298
ENSG00000101849	E015	0.8428203	0.0179735790	5.398022e-01	6.710363e-01	X	9534943	9534960	18	+	0.275	0.236	-0.295
ENSG00000101849	E016	1.1404508	0.0112474484	3.507239e-01	4.949096e-01	X	9534961	9535034	74	+	0.201	0.446	1.608
ENSG00000101849	E017	0.0000000				X	9542883	9543104	222	+
ENSG00000101849	E018	0.0000000				X	9543105	9543267	163	+
ENSG00000101849	E019	0.1515154	0.0430603590	4.264041e-01		X	9560465	9560548	84	+	0.112	0.000	-22.479
ENSG00000101849	E020	0.0000000				X	9636282	9637918	1637	+
ENSG00000101849	E021	0.0000000				X	9639820	9639935	116	+
ENSG00000101849	E022	70.2591772	0.0113523503	1.182699e-02	3.311735e-02	X	9640273	9640360	88	+	1.857	1.846	-0.037
ENSG00000101849	E023	0.1451727	0.0435011906	4.266165e-01		X	9644677	9645395	719	+	0.112	0.000	-22.474
ENSG00000101849	E024	34.9786188	0.0006376994	3.936570e-06	2.867800e-05	X	9653545	9653689	145	+	1.610	1.489	-0.414
ENSG00000101849	E025	89.3751615	0.0028578315	1.622786e-04	8.017313e-04	X	9654215	9654322	108	+	1.963	1.948	-0.047
ENSG00000101849	E026	2.0253064	0.0069041356	4.354700e-03	1.413467e-02	X	9654323	9656938	2616	+	0.627	0.235	-2.171
ENSG00000101849	E027	1.8028250	0.1341117221	7.245738e-01	8.180596e-01	X	9683746	9684042	297	+	0.338	0.507	0.911
ENSG00000101849	E028	109.0636333	0.0106182762	5.753285e-03	1.796334e-02	X	9684043	9684188	146	+	2.044	2.037	-0.023
ENSG00000101849	E029	168.8727020	0.0002280594	4.863223e-14	1.445213e-12	X	9688017	9688275	259	+	2.254	2.203	-0.171
ENSG00000101849	E030	148.8395585	0.0019629118	6.070602e-10	9.375978e-09	X	9691579	9691711	133	+	2.208	2.143	-0.217
ENSG00000101849	E031	163.7113287	0.0002616734	1.391120e-08	1.669688e-07	X	9692113	9692254	142	+	2.220	2.217	-0.009
ENSG00000101849	E032	132.3110894	0.0049332478	8.105782e-04	3.296587e-03	X	9693149	9693212	64	+	2.122	2.124	0.008
ENSG00000101849	E033	146.0665057	0.0004071521	1.591354e-08	1.889547e-07	X	9693322	9693419	98	+	2.175	2.160	-0.049
ENSG00000101849	E034	126.3611441	0.0012418244	1.924894e-09	2.705032e-08	X	9697369	9697429	61	+	2.133	2.079	-0.183
ENSG00000101849	E035	154.2791175	0.0030201737	4.550310e-08	4.948864e-07	X	9704993	9705114	122	+	2.219	2.166	-0.177
ENSG00000101849	E036	133.8061531	0.0019374918	9.114369e-08	9.321366e-07	X	9709248	9709322	75	+	2.151	2.111	-0.134
ENSG00000101849	E037	152.0682445	0.0040340023	3.114751e-06	2.321414e-05	X	9709633	9709760	128	+	2.203	2.166	-0.122
ENSG00000101849	E038	155.2193132	0.0025929066	9.876432e-04	3.916401e-03	X	9711611	9711776	166	+	2.176	2.210	0.113
ENSG00000101849	E039	5.2347391	0.0755319158	4.335763e-01	5.759867e-01	X	9711777	9713322	1546	+	0.799	0.783	-0.065
ENSG00000101849	E040	120.2971131	0.0002444718	1.943054e-04	9.395726e-04	X	9714902	9715003	102	+	2.068	2.103	0.116
ENSG00000101849	E041	2273.4120310	0.0067220318	2.426390e-17	1.124168e-15	X	9716220	9719740	3521	+	3.164	3.491	1.088
ENSG00000101849	E042	4.9936494	0.0270108151	7.075890e-01	8.054667e-01	X	9719997	9720058	62	+	0.684	0.871	0.745
ENSG00000101849	E043	1.6681491	0.0087571478	8.069463e-01	8.773685e-01	X	9740782	9741037	256	+	0.393	0.447	0.288

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000101849

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3