ENSG00000101849

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000407597 ENSG00000101849 HEK293_OSMI2_2hA HEK293_TMG_2hB TBL1X protein_coding protein_coding 19.79436 22.81654 19.49237 1.713333 0.4996396 -0.2270629 2.1770705 1.190179 4.439498 0.6430834 0.4445985 1.89039266 0.1116333 0.04883333 0.22903333 0.18020000 0.003141249 0.003141249 FALSE TRUE
ENST00000424279 ENSG00000101849 HEK293_OSMI2_2hA HEK293_TMG_2hB TBL1X protein_coding protein_coding 19.79436 22.81654 19.49237 1.713333 0.4996396 -0.2270629 2.7994010 4.467110 1.620229 1.1931388 0.9675673 -1.45749311 0.1364333 0.19413333 0.08190000 -0.11223333 0.577009289 0.003141249 FALSE TRUE
ENST00000683056 ENSG00000101849 HEK293_OSMI2_2hA HEK293_TMG_2hB TBL1X protein_coding protein_coding 19.79436 22.81654 19.49237 1.713333 0.4996396 -0.2270629 0.3266022 1.928125 0.000000 1.4067169 0.0000000 -7.59851756 0.0150500 0.08800000 0.00000000 -0.08800000 0.204455476 0.003141249 FALSE TRUE
MSTRG.33886.5 ENSG00000101849 HEK293_OSMI2_2hA HEK293_TMG_2hB TBL1X protein_coding   19.79436 22.81654 19.49237 1.713333 0.4996396 -0.2270629 9.0224232 9.790356 9.441110 2.9350906 1.0043522 -0.05235039 0.4569292 0.42320000 0.48696667 0.06376667 0.843036006 0.003141249 FALSE TRUE
MSTRG.33886.8 ENSG00000101849 HEK293_OSMI2_2hA HEK293_TMG_2hB TBL1X protein_coding   19.79436 22.81654 19.49237 1.713333 0.4996396 -0.2270629 3.5847237 4.470893 1.710541 0.8947182 0.8560477 -1.38092392 0.1834542 0.20396667 0.08576667 -0.11820000 0.620363582 0.003141249 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

No results under this category.

Splicing

All exons whithin this gene region are shown and numbering below.

No results under this category.

Transcripts

All isoforms whithin this gene region are shown below.

No results under this category.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000101849 E001 2.5754910 0.1369042591 1.210646e-01 2.214604e-01 X 9463320 9463328 9 + 0.656 0.442 -0.998
ENSG00000101849 E002 3.8654958 0.0039542913 2.916270e-02 7.031406e-02 X 9463329 9463330 2 + 0.779 0.588 -0.801
ENSG00000101849 E003 14.0679194 0.0013130590 6.361359e-06 4.424319e-05 X 9463331 9463462 132 + 1.291 1.030 -0.935
ENSG00000101849 E004 6.4454908 0.0044993242 4.235070e-02 9.536345e-02 X 9465058 9465293 236 + 0.922 0.806 -0.449
ENSG00000101849 E005 26.0396336 0.0253530742 9.276235e-03 2.697564e-02 X 9465294 9465447 154 + 1.479 1.367 -0.387
ENSG00000101849 E006 0.8803962 0.0144061202 2.291050e-01 3.613595e-01 X 9466196 9466426 231 + 0.112 0.387 2.288
ENSG00000101849 E007 0.6986918 0.0167907076 3.912141e-01 5.351409e-01 X 9466427 9466457 31 + 0.112 0.318 1.873
ENSG00000101849 E008 1.7327815 0.1334194418 8.570475e-01 9.116768e-01 X 9481612 9481638 27 + 0.394 0.452 0.315
ENSG00000101849 E009 0.0000000       X 9491366 9491513 148 +      
ENSG00000101849 E010 53.4134189 0.0142277691 2.904544e-04 1.341011e-03 X 9501780 9501849 70 + 1.790 1.669 -0.408
ENSG00000101849 E011 0.0000000       X 9530983 9531005 23 +      
ENSG00000101849 E012 0.0000000       X 9531006 9531038 33 +      
ENSG00000101849 E013 0.0000000       X 9531039 9531088 50 +      
ENSG00000101849 E014 0.8157519 0.0167528129 5.383202e-01 6.697565e-01 X 9534900 9534942 43 + 0.275 0.235 -0.298
ENSG00000101849 E015 0.8428203 0.0179735790 5.398022e-01 6.710363e-01 X 9534943 9534960 18 + 0.275 0.236 -0.295
ENSG00000101849 E016 1.1404508 0.0112474484 3.507239e-01 4.949096e-01 X 9534961 9535034 74 + 0.201 0.446 1.608
ENSG00000101849 E017 0.0000000       X 9542883 9543104 222 +      
ENSG00000101849 E018 0.0000000       X 9543105 9543267 163 +      
ENSG00000101849 E019 0.1515154 0.0430603590 4.264041e-01   X 9560465 9560548 84 + 0.112 0.000 -22.479
ENSG00000101849 E020 0.0000000       X 9636282 9637918 1637 +      
ENSG00000101849 E021 0.0000000       X 9639820 9639935 116 +      
ENSG00000101849 E022 70.2591772 0.0113523503 1.182699e-02 3.311735e-02 X 9640273 9640360 88 + 1.857 1.846 -0.037
ENSG00000101849 E023 0.1451727 0.0435011906 4.266165e-01   X 9644677 9645395 719 + 0.112 0.000 -22.474
ENSG00000101849 E024 34.9786188 0.0006376994 3.936570e-06 2.867800e-05 X 9653545 9653689 145 + 1.610 1.489 -0.414
ENSG00000101849 E025 89.3751615 0.0028578315 1.622786e-04 8.017313e-04 X 9654215 9654322 108 + 1.963 1.948 -0.047
ENSG00000101849 E026 2.0253064 0.0069041356 4.354700e-03 1.413467e-02 X 9654323 9656938 2616 + 0.627 0.235 -2.171
ENSG00000101849 E027 1.8028250 0.1341117221 7.245738e-01 8.180596e-01 X 9683746 9684042 297 + 0.338 0.507 0.911
ENSG00000101849 E028 109.0636333 0.0106182762 5.753285e-03 1.796334e-02 X 9684043 9684188 146 + 2.044 2.037 -0.023
ENSG00000101849 E029 168.8727020 0.0002280594 4.863223e-14 1.445213e-12 X 9688017 9688275 259 + 2.254 2.203 -0.171
ENSG00000101849 E030 148.8395585 0.0019629118 6.070602e-10 9.375978e-09 X 9691579 9691711 133 + 2.208 2.143 -0.217
ENSG00000101849 E031 163.7113287 0.0002616734 1.391120e-08 1.669688e-07 X 9692113 9692254 142 + 2.220 2.217 -0.009
ENSG00000101849 E032 132.3110894 0.0049332478 8.105782e-04 3.296587e-03 X 9693149 9693212 64 + 2.122 2.124 0.008
ENSG00000101849 E033 146.0665057 0.0004071521 1.591354e-08 1.889547e-07 X 9693322 9693419 98 + 2.175 2.160 -0.049
ENSG00000101849 E034 126.3611441 0.0012418244 1.924894e-09 2.705032e-08 X 9697369 9697429 61 + 2.133 2.079 -0.183
ENSG00000101849 E035 154.2791175 0.0030201737 4.550310e-08 4.948864e-07 X 9704993 9705114 122 + 2.219 2.166 -0.177
ENSG00000101849 E036 133.8061531 0.0019374918 9.114369e-08 9.321366e-07 X 9709248 9709322 75 + 2.151 2.111 -0.134
ENSG00000101849 E037 152.0682445 0.0040340023 3.114751e-06 2.321414e-05 X 9709633 9709760 128 + 2.203 2.166 -0.122
ENSG00000101849 E038 155.2193132 0.0025929066 9.876432e-04 3.916401e-03 X 9711611 9711776 166 + 2.176 2.210 0.113
ENSG00000101849 E039 5.2347391 0.0755319158 4.335763e-01 5.759867e-01 X 9711777 9713322 1546 + 0.799 0.783 -0.065
ENSG00000101849 E040 120.2971131 0.0002444718 1.943054e-04 9.395726e-04 X 9714902 9715003 102 + 2.068 2.103 0.116
ENSG00000101849 E041 2273.4120310 0.0067220318 2.426390e-17 1.124168e-15 X 9716220 9719740 3521 + 3.164 3.491 1.088
ENSG00000101849 E042 4.9936494 0.0270108151 7.075890e-01 8.054667e-01 X 9719997 9720058 62 + 0.684 0.871 0.745
ENSG00000101849 E043 1.6681491 0.0087571478 8.069463e-01 8.773685e-01 X 9740782 9741037 256 + 0.393 0.447 0.288