ENSG00000100075

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-2 / 2
Columns:
Select all:
isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
Close
Columns▼Records:
Use the filters above each column to filter and limit table data. Advanced searches can be performed by using the following operators:
<, <=, >, >=, =, *, !, {, }, ||,&&, **[empty]**, **[nonempty]**, **rgx:**
Learn more
TableFilter v0.7.3
https://www.tablefilter.com/
©2015-2025 Max Guglielmi
Close
?
Page of 1
isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000215882	ENSG00000100075	HEK293_OSMI2_2hA	HEK293_TMG_2hB	SLC25A1	protein_coding	protein_coding	197.3269	388.0087	104.9376	10.83819	1.705511	-1.886457	103.57088	162.0833	70.76870	13.468284	2.147672	-1.195437	0.5345583	0.4166	0.6742000	0.2576000	1.146965e-09	1.146965e-09	FALSE	TRUE
ENST00000451283	ENSG00000100075	HEK293_OSMI2_2hA	HEK293_TMG_2hB	SLC25A1	protein_coding	protein_coding	197.3269	388.0087	104.9376	10.83819	1.705511	-1.886457	66.64604	175.2077	17.88094	7.706578	2.451517	-3.291848	0.3233542	0.4528	0.1709667	-0.2818333	6.355204e-07	1.146965e-09	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 26
Columns:
Select all:
groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
Close
Columns▼Records:
Use the filters above each column to filter and limit table data. Advanced searches can be performed by using the following operators:
<, <=, >, >=, =, *, !, {, }, ||,&&, **[empty]**, **[nonempty]**, **rgx:**
Learn more
TableFilter v0.7.3
https://www.tablefilter.com/
©2015-2025 Max Guglielmi
Close
?
Page of 3
groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000100075	E001	0.0000000				22	19175258	19175320	63	-
ENSG00000100075	E002	0.0000000				22	19175321	19175375	55	-
ENSG00000100075	E003	0.1817044	0.0394522511	1.000000e+00		22	19175376	19175460	85	-	0.000	0.066	7.930
ENSG00000100075	E004	0.1817044	0.0394522511	1.000000e+00		22	19175461	19175501	41	-	0.000	0.066	7.909
ENSG00000100075	E005	7.4103648	0.0037547864	1.885445e-01	3.119050e-01	22	19175502	19175580	79	-	0.626	0.840	0.876
ENSG00000100075	E006	119.2814877	0.0043725795	2.447133e-03	8.604343e-03	22	19175581	19175591	11	-	1.812	1.990	0.598
ENSG00000100075	E007	219.9039751	0.0038616599	1.344696e-01	2.403697e-01	22	19175592	19175592	1	-	2.163	2.237	0.248
ENSG00000100075	E008	356.7540559	0.0040413156	4.644477e-05	2.637066e-04	22	19175593	19175609	17	-	2.283	2.460	0.591
ENSG00000100075	E009	1044.8427516	0.0003502329	7.642021e-24	7.462670e-22	22	19175610	19175685	76	-	2.739	2.926	0.620
ENSG00000100075	E010	5713.4090886	0.0018687459	2.089206e-08	2.426843e-07	22	19175686	19176244	559	-	3.542	3.654	0.371
ENSG00000100075	E011	2448.4682818	0.0010472656	7.982973e-02	1.593021e-01	22	19176421	19176494	74	-	3.236	3.275	0.130
ENSG00000100075	E012	2596.8960938	0.0004308494	1.738488e-01	2.931945e-01	22	19176578	19176666	89	-	3.301	3.292	-0.027
ENSG00000100075	E013	1832.4867210	0.0001177999	7.333931e-04	3.019431e-03	22	19176667	19176693	27	-	3.166	3.136	-0.100
ENSG00000100075	E014	2664.6513165	0.0002217129	6.479279e-02	1.347030e-01	22	19176846	19176942	97	-	3.313	3.302	-0.038
ENSG00000100075	E015	1262.5557669	0.0016456183	1.253663e-02	3.481933e-02	22	19176943	19176950	8	-	3.019	2.971	-0.159
ENSG00000100075	E016	1961.1588353	0.0004703909	1.293594e-02	3.576217e-02	22	19177120	19177204	85	-	3.193	3.166	-0.088
ENSG00000100075	E017	1584.4350400	0.0032621758	2.453808e-01	3.804793e-01	22	19177727	19177865	139	-	3.099	3.075	-0.079
ENSG00000100075	E018	48.0482763	0.0028477828	4.434845e-07	3.963992e-06	22	19177866	19177941	76	-	1.799	1.496	-1.029
ENSG00000100075	E019	659.2115571	0.0017608088	1.312607e-01	2.359004e-01	22	19177942	19177946	5	-	2.723	2.692	-0.103
ENSG00000100075	E020	975.6403289	0.0016946190	3.756550e-01	5.200648e-01	22	19177947	19177989	43	-	2.878	2.866	-0.039
ENSG00000100075	E021	920.7396952	0.0020838060	3.289545e-01	4.724308e-01	22	19177990	19178041	52	-	2.856	2.840	-0.053
ENSG00000100075	E022	21.0251592	0.0045944470	3.962943e-04	1.760134e-03	22	19178042	19178132	91	-	1.458	1.156	-1.057
ENSG00000100075	E023	1115.3722553	0.0033753835	5.993784e-05	3.311474e-04	22	19178133	19178240	108	-	3.016	2.905	-0.369
ENSG00000100075	E024	96.0688204	0.0186643939	7.843127e-01	8.616610e-01	22	19178241	19178386	146	-	1.875	1.863	-0.041
ENSG00000100075	E025	153.6896766	0.0018206664	7.161489e-02	1.460270e-01	22	19178387	19178579	193	-	2.118	2.053	-0.220
ENSG00000100075	E026	456.8311850	0.0063808268	2.517931e-21	1.874320e-19	22	19178580	19178892	313	-	2.834	2.440	-1.311

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000100075

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3