ENSG00000092929

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000207549 ENSG00000092929 HEK293_OSMI2_2hA HEK293_TMG_2hB UNC13D protein_coding protein_coding 0.3506324 0.1912737 0.4224524 0.03759296 0.06636802 1.103383 0.09461168 0.16741715 0.10740484 0.034589080 0.010576552 -0.5956537 0.35528750 0.873 0.2586667 -0.6143333 0.001167879 0.001167879 FALSE TRUE
ENST00000586519 ENSG00000092929 HEK293_OSMI2_2hA HEK293_TMG_2hB UNC13D protein_coding nonsense_mediated_decay 0.3506324 0.1912737 0.4224524 0.03759296 0.06636802 1.103383 0.04534199 0.00000000 0.00000000 0.000000000 0.000000000 0.0000000 0.08178750 0.000 0.0000000 0.0000000   0.001167879   FALSE
ENST00000587495 ENSG00000092929 HEK293_OSMI2_2hA HEK293_TMG_2hB UNC13D protein_coding retained_intron 0.3506324 0.1912737 0.4224524 0.03759296 0.06636802 1.103383 0.05670581 0.00000000 0.00000000 0.000000000 0.000000000 0.0000000 0.09196667 0.000 0.0000000 0.0000000   0.001167879   FALSE
ENST00000588774 ENSG00000092929 HEK293_OSMI2_2hA HEK293_TMG_2hB UNC13D protein_coding retained_intron 0.3506324 0.1912737 0.4224524 0.03759296 0.06636802 1.103383 0.01305078 0.00000000 0.05141711 0.000000000 0.029856024 2.6186407 0.02904583 0.000 0.1072667 0.1072667 0.448724225 0.001167879 FALSE TRUE
ENST00000590856 ENSG00000092929 HEK293_OSMI2_2hA HEK293_TMG_2hB UNC13D protein_coding retained_intron 0.3506324 0.1912737 0.4224524 0.03759296 0.06636802 1.103383 0.02586600 0.00000000 0.05040609 0.000000000 0.025203805 2.5946940 0.07253333 0.000 0.1416333 0.1416333 0.521506754 0.001167879 FALSE TRUE
ENST00000591563 ENSG00000092929 HEK293_OSMI2_2hA HEK293_TMG_2hB UNC13D protein_coding retained_intron 0.3506324 0.1912737 0.4224524 0.03759296 0.06636802 1.103383 0.03131228 0.02385653 0.04760506 0.004716165 0.007992943 0.7667616 0.16031667 0.127 0.1199000 -0.0071000 0.864272914 0.001167879 FALSE TRUE
ENST00000591616 ENSG00000092929 HEK293_OSMI2_2hA HEK293_TMG_2hB UNC13D protein_coding retained_intron 0.3506324 0.1912737 0.4224524 0.03759296 0.06636802 1.103383 0.07285958 0.00000000 0.16561930 0.000000000 0.056021510 4.1343795 0.18171250 0.000 0.3724667 0.3724667 0.014171757 0.001167879 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000092929 E001 0.1451727 0.051463886 0.437304542   17 75827225 75827263 39 - 0.130 0.000 -13.307
ENSG00000092929 E002 1.9143710 0.008668239 0.175795310 0.29571656 17 75827264 75827445 182 - 0.311 0.536 1.221
ENSG00000092929 E003 2.1253234 0.038909268 0.647097937 0.75884100 17 75827446 75827658 213 - 0.536 0.452 -0.413
ENSG00000092929 E004 3.1228908 0.204570911 0.379059680 0.52334800 17 75827659 75827956 298 - 0.489 0.674 0.838
ENSG00000092929 E005 1.3651183 0.010065027 0.587830183 0.71108726 17 75827957 75827997 41 - 0.311 0.402 0.543
ENSG00000092929 E006 2.1253470 0.195497035 0.237788169 0.37157797 17 75827998 75828086 89 - 0.311 0.579 1.418
ENSG00000092929 E007 2.1596901 0.164060887 0.323028282 0.46637102 17 75828787 75828983 197 - 0.378 0.571 0.971
ENSG00000092929 E008 0.4449813 0.025074281 0.497998651 0.63450895 17 75829662 75830027 366 - 0.229 0.115 -1.197
ENSG00000092929 E009 1.4652516 0.311226988 0.488093133 0.62570394 17 75830028 75830147 120 - 0.310 0.447 0.790
ENSG00000092929 E010 0.6203429 0.025318279 0.904174327 0.94300515 17 75830148 75830151 4 - 0.229 0.206 -0.196
ENSG00000092929 E011 1.2803381 0.500428312 0.382926019 0.52708547 17 75830362 75830437 76 - 0.229 0.441 1.344
ENSG00000092929 E012 1.1780267 0.034948065 0.006322262 0.01946318 17 75830438 75830482 45 - 0.000 0.494 15.453
ENSG00000092929 E013 1.5509873 0.010238371 0.020323277 0.05216354 17 75830578 75830661 84 - 0.130 0.536 2.804
ENSG00000092929 E014 1.0360631 0.078573133 0.017158033 0.04529167 17 75831098 75831169 72 - 0.000 0.449 15.228
ENSG00000092929 E015 1.1155605 0.012657272 0.594320502 0.71657292 17 75831243 75831294 52 - 0.379 0.282 -0.611
ENSG00000092929 E016 0.8189741 0.015796514 0.132533154 0.23759648 17 75831295 75831300 6 - 0.379 0.115 -2.193
ENSG00000092929 E017 1.1919347 0.083124519 0.222091447 0.35290750 17 75831301 75831348 48 - 0.438 0.208 -1.502
ENSG00000092929 E018 0.7728905 0.015724677 0.133481135 0.23897710 17 75831349 75832965 1617 - 0.379 0.115 -2.194
ENSG00000092929 E019 1.4949656 0.312502966 0.184454112 0.30681135 17 75832966 75833045 80 - 0.538 0.213 -1.956
ENSG00000092929 E020 0.0000000       17 75833193 75833269 77 -      
ENSG00000092929 E021 0.9747559 0.269995959 0.153561932 0.26651625 17 75834075 75834143 69 - 0.439 0.117 -2.498
ENSG00000092929 E022 1.7778078 0.300755390 0.491219105 0.62852039 17 75834325 75834531 207 - 0.490 0.361 -0.689
ENSG00000092929 E023 1.9187141 0.013656471 0.272768923 0.41172453 17 75834618 75834716 99 - 0.536 0.347 -0.996
ENSG00000092929 E024 2.1014626 0.008793320 0.838643133 0.89914219 17 75834920 75835063 144 - 0.490 0.452 -0.191
ENSG00000092929 E025 0.5911862 0.018425891 0.027874443 0.06776615 17 75835064 75835272 209 - 0.379 0.000 -15.316
ENSG00000092929 E026 0.9201370 0.014241081 0.209946540 0.33846537 17 75835409 75835418 10 - 0.130 0.346 1.808
ENSG00000092929 E027 1.2199456 0.011150808 0.318571626 0.46154112 17 75835419 75835529 111 - 0.229 0.402 1.128
ENSG00000092929 E028 0.8167960 0.015378759 0.753398036 0.83935522 17 75835647 75835716 70 - 0.230 0.281 0.389
ENSG00000092929 E029 0.9619687 0.013823926 0.881764540 0.92823329 17 75835717 75835777 61 - 0.311 0.281 -0.195
ENSG00000092929 E030 0.4375944 0.068995684 0.072537012 0.14757309 17 75835855 75835906 52 - 0.310 0.000 -14.900
ENSG00000092929 E031 0.8804848 0.129581547 0.560222487 0.68823784 17 75836012 75836109 98 - 0.310 0.209 -0.752
ENSG00000092929 E032 1.0309535 0.506066528 0.550936860 0.68048412 17 75836200 75836256 57 - 0.129 0.368 1.941
ENSG00000092929 E033 0.8857808 0.638783970 0.269733296 0.40827545 17 75836339 75836429 91 - 0.000 0.371 14.803
ENSG00000092929 E034 0.5901394 0.048514230 0.649054616 0.76044361 17 75836572 75836593 22 - 0.130 0.208 0.816
ENSG00000092929 E035 1.1103491 0.016034559 0.882902959 0.92907548 17 75836594 75836696 103 - 0.311 0.282 -0.190
ENSG00000092929 E036 0.8157519 0.015580012 0.564985001 0.69217203 17 75836801 75836918 118 - 0.311 0.206 -0.779
ENSG00000092929 E037 0.1472490 0.042694898 0.440547858   17 75839839 75839846 8 - 0.130 0.000 -13.316
ENSG00000092929 E038 0.8459408 0.015903626 0.746431911 0.83420417 17 75839847 75839942 96 - 0.229 0.282 0.391
ENSG00000092929 E039 0.2214452 0.036695873 0.543698628   17 75839943 75840017 75 - 0.000 0.116 12.656
ENSG00000092929 E040 1.3671946 0.010380204 0.584325467 0.70829040 17 75840018 75840110 93 - 0.311 0.402 0.543
ENSG00000092929 E041 0.1515154 0.045724004 0.437961146   17 75840111 75840224 114 - 0.130 0.000 -13.317
ENSG00000092929 E042 1.3285997 0.011599331 0.869028954 0.91983042 17 75840225 75840304 80 - 0.379 0.346 -0.194
ENSG00000092929 E043 0.8481309 0.015437189 0.754843326 0.84035562 17 75840305 75840329 25 - 0.229 0.282 0.391
ENSG00000092929 E044 0.5546650 0.021957227 0.639215715 0.75265392 17 75840330 75840367 38 - 0.130 0.207 0.808
ENSG00000092929 E045 0.8136755 0.014927884 0.560496594 0.68848976 17 75840507 75840576 70 - 0.311 0.206 -0.779
ENSG00000092929 E046 0.0000000       17 75840755 75840761 7 -      
ENSG00000092929 E047 0.3686942 0.026551453 0.930858868 0.96050269 17 75840762 75840793 32 - 0.130 0.116 -0.192
ENSG00000092929 E048 0.2987644 0.029078516 0.171745102   17 75840794 75840830 37 - 0.230 0.000 -14.317
ENSG00000092929 E049 0.7427016 0.015909624 0.011777912 0.03300139 17 75840957 75841001 45 - 0.438 0.000 -15.638
ENSG00000092929 E050 0.0000000       17 75841002 75841032 31 -      
ENSG00000092929 E051 0.0000000       17 75841033 75841156 124 -      
ENSG00000092929 E052 0.7458221 0.016521115 0.133293196 0.23870544 17 75842433 75842492 60 - 0.379 0.115 -2.196
ENSG00000092929 E053 0.4502799 0.027565932 0.068197855 0.14038159 17 75842493 75842613 121 - 0.311 0.000 -14.902
ENSG00000092929 E054 0.0000000       17 75842857 75842923 67 -      
ENSG00000092929 E055 0.0000000       17 75843014 75843073 60 -      
ENSG00000092929 E056 0.2955422 0.029387108 0.933167722   17 75843159 75843248 90 - 0.130 0.115 -0.197
ENSG00000092929 E057 0.2955422 0.029387108 0.933167722   17 75843249 75843266 18 - 0.130 0.115 -0.197
ENSG00000092929 E058 0.2955422 0.029387108 0.933167722   17 75843484 75843519 36 - 0.130 0.115 -0.197
ENSG00000092929 E059 0.1472490 0.042694898 0.440547858   17 75843520 75843662 143 - 0.130 0.000 -13.316
ENSG00000092929 E060 0.0000000       17 75843663 75843744 82 -      
ENSG00000092929 E061 0.0000000       17 75843745 75843755 11 -      
ENSG00000092929 E062 0.0000000       17 75843756 75843769 14 -      
ENSG00000092929 E063 0.2924217 0.028497106 0.171027427   17 75843770 75844220 451 - 0.229 0.000 -14.316
ENSG00000092929 E064 0.4407149 0.023905988 0.501233626 0.63738306 17 75844221 75844313 93 - 0.229 0.115 -1.196
ENSG00000092929 E065 0.1482932 0.044143149 0.543398474   17 75844314 75844334 21 - 0.000 0.115 12.649
ENSG00000092929 E066 0.1482932 0.044143149 0.543398474   17 75844335 75844350 16 - 0.000 0.115 12.649
ENSG00000092929 E067 0.1482932 0.044143149 0.543398474   17 75844351 75844360 10 - 0.000 0.115 12.649
ENSG00000092929 E068 0.0000000       17 75844361 75844371 11 -      
ENSG00000092929 E069 0.0000000       17 75844372 75844404 33 -      
ENSG00000092929 E070 0.0000000       17 75844405 75844418 14 -      
ENSG00000092929 E071 0.0000000       17 75844521 75844552 32 -