ENSG00000091428

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-5 / 5
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000397081	ENSG00000091428	HEK293_OSMI2_2hA	HEK293_TMG_2hB	RAPGEF4	protein_coding	protein_coding	2.350621	1.499645	4.357261	0.2262323	0.02551067	1.532519	1.28796332	1.06426667	2.0616935	0.01167894	0.1608956	0.9474584	0.578641667	0.74770000	0.47303333	-0.27466667	3.779916e-01	7.543015e-05	FALSE	TRUE
ENST00000397085	ENSG00000091428	HEK293_OSMI2_2hA	HEK293_TMG_2hB	RAPGEF4	protein_coding	protein_coding	2.350621	1.499645	4.357261	0.2262323	0.02551067	1.532519	0.40561710	0.36281408	0.4011621	0.18491566	0.2012240	0.1412511	0.180208333	0.21050000	0.09190000	-0.11860000	7.087389e-01	7.543015e-05	FALSE	TRUE
ENST00000473003	ENSG00000091428	HEK293_OSMI2_2hA	HEK293_TMG_2hB	RAPGEF4	protein_coding	processed_transcript	2.350621	1.499645	4.357261	0.2262323	0.02551067	1.532519	0.03826089	0.00000000	0.3060871	0.00000000	0.3060871	4.9822503	0.008879167	0.00000000	0.07103333	0.07103333	1.000000e+00	7.543015e-05	FALSE	FALSE
ENST00000484331	ENSG00000091428	HEK293_OSMI2_2hA	HEK293_TMG_2hB	RAPGEF4	protein_coding	processed_transcript	2.350621	1.499645	4.357261	0.2262323	0.02551067	1.532519	0.20757634	0.05035676	0.7629379	0.05035676	0.1249417	3.6787652	0.062558333	0.02886667	0.17480000	0.14593333	3.810376e-02	7.543015e-05	FALSE	FALSE
MSTRG.19506.9	ENSG00000091428	HEK293_OSMI2_2hA	HEK293_TMG_2hB	RAPGEF4	protein_coding		2.350621	1.499645	4.357261	0.2262323	0.02551067	1.532519	0.19856130	0.00000000	0.6583745	0.00000000	0.1340166	6.0625848	0.071800000	0.00000000	0.15106667	0.15106667	7.543015e-05	7.543015e-05	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
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width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000091428	E001	0.7437457	0.0153787590	0.54036553	0.67152059	2	172735274	172735405	132	+	0.280	0.167	-0.953
ENSG00000091428	E002	2.9560551	0.0052432478	0.10137531	0.19256470	2	172735845	172735966	122	+	0.665	0.381	-1.365
ENSG00000091428	E003	5.6916194	0.0039210399	0.47326621	0.61225492	2	172735967	172736048	82	+	0.852	0.754	-0.385
ENSG00000091428	E004	0.0000000				2	172744138	172744423	286	+
ENSG00000091428	E005	13.1844137	0.0125424477	0.74711418	0.83470185	2	172795025	172795167	143	+	1.157	1.118	-0.137
ENSG00000091428	E006	13.5841004	0.0028406911	0.87397620	0.92300674	2	172797525	172797613	89	+	1.150	1.163	0.048
ENSG00000091428	E007	20.0808225	0.0062645256	0.71925753	0.81414166	2	172814279	172814425	147	+	1.320	1.285	-0.123
ENSG00000091428	E008	0.1515154	0.0436401724	1.00000000		2	172814426	172814740	315	+	0.089	0.000	-8.216
ENSG00000091428	E009	0.0000000				2	172821575	172821976	402	+
ENSG00000091428	E010	0.4545463	0.7432458243	0.58570957	0.70935542	2	172860038	172860299	262	+	0.227	0.000	-9.815
ENSG00000091428	E011	0.0000000				2	172889801	172889883	83	+
ENSG00000091428	E012	16.4881040	0.0011093811	0.64800857	0.75959319	2	172917802	172917874	73	+	1.214	1.252	0.131
ENSG00000091428	E013	10.2976110	0.0016461891	0.90120608	0.94099731	2	172922281	172922300	20	+	1.048	1.034	-0.051
ENSG00000091428	E014	0.0000000				2	172928152	172928204	53	+
ENSG00000091428	E015	0.0000000				2	172928205	172928224	20	+
ENSG00000091428	E016	0.0000000				2	172928225	172928346	122	+
ENSG00000091428	E017	12.2000994	0.0014998011	0.03103361	0.07398136	2	172960760	172960813	54	+	1.177	0.952	-0.818
ENSG00000091428	E018	17.9052184	0.0062026810	0.22477719	0.35616732	2	172961122	172961228	107	+	1.301	1.190	-0.391
ENSG00000091428	E019	0.0000000				2	172965141	172965561	421	+
ENSG00000091428	E020	14.8079680	0.0012919738	0.12401944	0.22570402	2	172965562	172965683	122	+	1.232	1.088	-0.516
ENSG00000091428	E021	0.5159433	0.2097087091	0.94407478	0.96895761	2	172967109	172967260	152	+	0.162	0.169	0.070
ENSG00000091428	E022	19.1364014	0.0010478456	0.18976241	0.31346389	2	172967261	172967444	184	+	1.325	1.216	-0.382
ENSG00000091428	E023	12.7075244	0.0013986443	0.01496601	0.04040911	2	172983496	172983580	85	+	1.202	0.952	-0.908
ENSG00000091428	E024	13.1086718	0.0013716270	0.02500233	0.06187855	2	172985433	172985493	61	+	1.202	0.974	-0.825
ENSG00000091428	E025	13.0771440	0.0014040269	0.63947495	0.75285622	2	172988196	172988272	77	+	1.150	1.104	-0.165
ENSG00000091428	E026	0.0000000				2	172988273	172988273	1	+
ENSG00000091428	E027	16.1643688	0.0011406727	0.03507287	0.08178993	2	172988693	172988839	147	+	1.150	1.325	0.617
ENSG00000091428	E028	16.3782273	0.0011286394	0.07941800	0.15860911	2	172990810	172990925	116	+	1.170	1.315	0.510
ENSG00000091428	E029	13.2192041	0.0015167634	0.43575120	0.57793975	2	172996466	172996554	89	+	1.106	1.177	0.256
ENSG00000091428	E030	9.5332042	0.0020813425	0.10271508	0.19463930	2	173001266	173001344	79	+	1.066	0.878	-0.698
ENSG00000091428	E031	16.7856102	0.0012030823	0.80680911	0.87729481	2	173014464	173014614	151	+	1.232	1.252	0.069
ENSG00000091428	E032	15.2664768	0.0013271605	0.48411674	0.62213884	2	173016349	173016437	89	+	1.226	1.163	-0.224
ENSG00000091428	E033	10.2977418	0.0168543520	0.21488966	0.34430726	2	173017174	173017204	31	+	1.098	0.949	-0.547
ENSG00000091428	E034	14.3296009	0.0018323307	0.34126514	0.48518422	2	173017426	173017504	79	+	1.208	1.119	-0.318
ENSG00000091428	E035	20.1344307	0.0009126255	0.60742141	0.72740594	2	173018656	173018802	147	+	1.296	1.334	0.133
ENSG00000091428	E036	20.2770325	0.0010057760	0.05421751	0.11662838	2	173020618	173020715	98	+	1.260	1.404	0.501
ENSG00000091428	E037	17.1762117	0.0010984044	0.23156294	0.36433546	2	173026572	173026625	54	+	1.208	1.305	0.340
ENSG00000091428	E038	17.5114962	0.0010419340	0.32545900	0.46890481	2	173026626	173026697	72	+	1.226	1.305	0.277
ENSG00000091428	E039	19.4408089	0.0010118000	0.70110335	0.80039748	2	173027081	173027259	179	+	1.286	1.315	0.101
ENSG00000091428	E040	11.3105659	0.0026164938	0.29010711	0.43089771	2	173030164	173030254	91	+	1.030	1.135	0.378
ENSG00000091428	E041	12.1050254	0.0057073654	0.22080878	0.35140170	2	173033914	173033964	51	+	1.057	1.177	0.432
ENSG00000091428	E042	14.4262819	0.0013434792	0.87344792	0.92267251	2	173036125	173036212	88	+	1.177	1.190	0.048
ENSG00000091428	E043	10.1870935	0.0122330514	0.59411072	0.71638837	2	173036628	173036692	65	+	1.012	1.071	0.215
ENSG00000091428	E044	2.1359194	0.0081569583	0.31396922	0.45662752	2	173036693	173036795	103	+	0.412	0.581	0.827
ENSG00000091428	E045	0.6224193	0.0172671820	0.47439257	0.61322804	2	173036946	173036974	29	+	0.162	0.287	1.048
ENSG00000091428	E046	1.5521107	0.0088192780	0.38235497	0.52658899	2	173048128	173048599	472	+	0.449	0.287	-0.951
ENSG00000091428	E047	7.0159396	0.0024677049	0.83951784	0.89973885	2	173048600	173048654	55	+	0.904	0.878	-0.098
ENSG00000091428	E048	36.6370368	0.0006809287	0.03433117	0.08039676	2	173051640	173052893	1254	+	1.511	1.630	0.406

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000091428

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3